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Ciclopirox ethanolamine

Ciclopirox ethanolamine
Ciclopirox ethanolamine structure
CAS No.
41621-49-2
Chemical Name:
Ciclopirox ethanolamine
Synonyms
terit;hoe296;lorpox;batrafen;Cicloche;C14H24N5O3;Micoxalamina;ciclopiroxolamin;CICLOPIROXOLAMINE;Ciclobiroxolamine
CBNumber:
CB0673864
Molecular Formula:
C14H24N2O3
Formula Weight:
268.35
MOL File:
41621-49-2.mol

Ciclopirox ethanolamine Properties

Melting point:
144 C
solubility 
Sparingly soluble in water, very soluble in ethanol (96 per cent) and in methylene chloride, slightly soluble in ethyl acetate, practically insoluble in cyclohexane.
form 
neat
CAS DataBase Reference
41621-49-2(CAS DataBase Reference)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-42/43-20/22
Safety Statements  26-36-22
WGK Germany  2
RTECS  UU7785500
Toxicity LD50 in mice, rats (mg/kg): 2898, 3290 orally (Alpermann, Schutz)
Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Ciclopirox ethanolamine price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C2162700 Ciclopirox olamine European Pharmacopoeia (EP) Reference Standard 41621-49-2 c2162700 $179 2018-11-23 Buy
Sigma-Aldrich 1134030 Ciclopirox olamine United States Pharmacopeia (USP) Reference Standard 41621-49-2 125mg $286.65 2018-11-20 Buy
TCI Chemical C3545 Ciclopirox Olamine >98.0%(HPLC)(T) 41621-49-2 1g $16 2018-11-22 Buy
TCI Chemical C3545 Ciclopirox Olamine >98.0%(HPLC)(T) 41621-49-2 5g $54 2018-11-22 Buy

Ciclopirox ethanolamine Chemical Properties,Uses,Production

Chemical Properties

White or pale yellow, crystalline powder.

Uses

antibacterial, antifungal, antiseborrheic

Uses

Ciclopirox ethanolamine is a broad spectrum antimycotic agent with some antibacterial activity.

Definition

ChEBI: The ethanolamine salt of ciclopirox. A broad spectrum antigfungal agent, it also exhibits antibacterial activity against many Gram-positive and Gram-negative bacteria, and has anti-inflammatory properties. It is used a a topical treatment of fungal skin an nail infections.

brand name

Loprox (Hoechst- Roussel).

Clinical Use

6-Cyclohexyl-1-hydroxyl-4-methyl-2(1H)-pyridinoneethanolamine salt (Loprox) is a broad-spectrum antifungalagent intended only for topical use. It is active against dermatophytesas well as pathogenic yeasts (C. albicans) thatare causative agents for superficial fungal infections.
Ciclopirox is considered an agent of choice in the treatmentof cutaneous candidiasis, tinea corporis, tinea cruris,tinea pedis, and tinea versicolor. It is a second-line agent forthe treatment of onychomycosis (ringworm of the nails).Loprox is formulated as a cream and a lotion, each containing1% of the water-soluble ethanolamine salt. Ciclopirox isbelieved to act on cell membranes of susceptible fungi atlow concentrations to block the transport of amino acids intothe cells. At higher concentrations, membrane integrity islost, and cellular constituents leak out.

Clinical Use

Ciclopirox olamine (Loprox) is a pyridone derivative available for the treatment of cutaneous dermatophyte infections, cutaneous C. albicans infections, and tinea versicolor caused by Malassezia furfur. It interferes with fungal growth by inhibiting macromolecule synthesis.

Ciclopirox ethanolamine Preparation Products And Raw materials

Raw materials

Preparation Products


Ciclopirox ethanolamine Suppliers

Global( 209)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 25796 58
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21935 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20676 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32452 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070;product@chemlin.com.cn
product@chemlin.com.cn CHINA 3015 60
Xiamen AmoyChem Co., Ltd
+86 (0)592-605 1114
sales@amoychem.com CHINA 6374 58
Hebei Chisure Biotechnology Co., Ltd.
+8613292890173
0311 66567340 luna@speedgainpharma.com CHINA 1019 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23958 58
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254
peter@hubeijusheng.com CHINA 20084 58
Haihang Industry Co.,Ltd
86-531-88032799
+86 531 8582 1093 export@haihangchem.com CHINA 8266 58

View Lastest Price from Ciclopirox ethanolamine manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-21 Ciclopirox ethanolamine
41621-49-2
US $7.00 / kg 1kg 99% 100kg career henan chemical co
2019-04-24 Ciclopirox ethanolamine
41621-49-2
US $10.00 / kg 1kg 99% 500tons/month Hebei Chisure Biotechnology Co., Ltd.

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