ANTI-NEUROFILAMENT 200
- CAS No.
- Chemical Name:
- ANTI-NEUROFILAMENT 200
- Synonyms
- ANTI-NF-H;ANTI-NEUROFILAMENT 200;ANTI-NEUROFILAMENT NF-H;ANTI-NEUROFILAMENT HEAVY;ANTI-NEUROFILAMENT 200KD;ANTI-NEUROFILAMENT 200 KDA;ANTI-NEUROFILAMENT P (200 KD);ANTI-HUMAN NEUROFILAMENT-HEAVY;ANTI-BOVINE NEUROFILAMENTS 200;ANTI-NEUROFILAMENT, RAT, 200 KD
- CBNumber:
- CB0681580
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD02263444
- MOL File:
- Mol file
ANTI-NEUROFILAMENT 200 price More Price(9)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | N5389 | Monoclonal Anti-Neurofilament 200 antibody produced in mouse clone NE14, ascites fluid | 100μL | $470 | 2024-03-01 | Buy | |
Sigma-Aldrich | WH0004744M1 | Monoclonal Anti-NEFH antibody produced in mouse clone 2E8, purified immunoglobulin, buffered aqueous solution | 100μg | $524 | 2024-03-01 | Buy | |
Sigma-Aldrich | N5389 | Monoclonal Anti-Neurofilament 200 antibody produced in mouse clone NE14, ascites fluid | 0.2mL | $627 | 2024-03-01 | Buy | |
Sigma-Aldrich | N4142 | Anti-Neurofilament 200 antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution | 25μL | $167 | 2024-03-01 | Buy | |
Sigma-Aldrich | N4142 | Anti-Neurofilament 200 antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution | 0.2mL | $574 | 2024-03-01 | Buy |
ANTI-NEUROFILAMENT 200 Chemical Properties,Uses,Production
Uses
Monoclonal Anti-Neurofilament 200 antibody produced in mouse has been used in
- immunohistochemistry
- immunolabeling
- immunofluorescence
Uses
Anti-neurofilament 200 antibody produced in rabbit has been used for immunolabeling.
Anti-neurofilament 200 antibody produced in rabbit has been used:
- for detection of neurofilaments using immunohistological staining
- in human astrocytoma cell line
- in post-mortem brain sections
- in human cremaster muscles
- for detection of neurofilaments by immunofluorescence staining in lumbar spinal cord sections of mice
General Description
Neurofilament 200, also known as neurofilament heavy polypeptide (NEFH), is encoded by the gene mapped to human chromosome 22q12.2. The encoded protein has a molecular mass of 200kDa and belongs to the group of type IV intermediate filaments which are key constituents of the neuronal cytoskeleton. NEFH contains C-terminal motifs involved in the formation of sidearm projections which cross-link the neurofilaments.
Biochem/physiol Actions
Neurofilament 200 plays a vital role in cytoarchitecture organization. Downregulated expression of the gene has been observed in schizophrenia patients. Loss of gene expression is associated with the development of prostate carcinoma. Mutation in the gene leads to sporadic amyotrophic lateral sclerosis (ALS). Neurofilament 200 assembly during development is critical for normal functioning of neuronal cells. Mutations in gene encoding neurofilaments is associated with neurological disorder called the Charcot–Marie–Tooth.
ANTI-NEUROFILAMENT 200 Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-NEUROFILAMENT 200 Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Supplier | Advantage |
---|---|
3B Pharmachem (Wuhan) International Co.,Ltd. | 69 |
Sigma-Aldrich | 80 |