ACETOACETYL COENZYME A SODIUM SALT
- CAS No.
- 102029-52-7
- Chemical Name:
- ACETOACETYL COENZYME A SODIUM SALT
- Synonyms
- Acetyl-CoA oxidase;Acetoacetyl coenzyme A;ACETOACETYL COENZYME A SODIUM;ACETOACETYL COENZYME A SODIUM SALT;S-(3-oxobutanoate)-CoA,tetrasodiumsalt;ACETOACETYL COENZYME A TRISODIUM SALT &;Acetoacetyl coenzyme A hydrate sodium salt;Acetoacetyl coenzyme A trisodium salt tetrahydrate;Coenzyme A,S-(3-oxobutanoate), tetrasodium salt (9CI);coenzyme A acetoacetyl derivative trisodium salt hydrate
- CBNumber:
- CB0692964
- Molecular Formula:
- C25H37N7Na3O18P3S
- Molecular Weight:
- 917.55
- MDL Number:
- MFCD00084766
- MOL File:
- 102029-52-7.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Acetoacetyl Coenzyme A, Trisodium Salt Tetrahydrate | 235095 | 5mg | $355 |
| Acetoacetyl coenzyme A trisodium salt tetrahydrate | NA47206 | 10mg | $750 |
| ACETOACETYL COENZYME A SODIUM SALT 95.00% | ENZ0008576 | 5MG | $859.62 |
| Acetoacetyl coenzyme A trisodium salt tetrahydrate | NA47206 | 50mg | $2500 |
SAFETY
Risk and Safety Statements
| WGK Germany | 3 |
|---|---|
| F | 10-21 |
ACETOACETYL COENZYME A SODIUM SALT price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 235095 | Acetoacetyl Coenzyme A, Trisodium Salt Tetrahydrate | 102029-52-7 | 5mg | $355 | 2021-12-16 | Buy |
| Biosynth Carbosynth | NA47206 | Acetoacetyl coenzyme A trisodium salt tetrahydrate | 102029-52-7 | 10mg | $750 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | ENZ0008576 | ACETOACETYL COENZYME A SODIUM SALT 95.00% | 102029-52-7 | 5MG | $859.62 | 2021-12-16 | Buy |
| Biosynth Carbosynth | NA47206 | Acetoacetyl coenzyme A trisodium salt tetrahydrate | 102029-52-7 | 50mg | $2500 | 2021-12-16 | Buy |
ACETOACETYL COENZYME A SODIUM SALT Chemical Properties,Uses,Production
Uses
Acetoacetyl coenzyme A sodium is a central endogenous metabolite. The Km at pH 7.5 for Acetoacetyl coenzyme A sodium is 1.10 mM. Acetoacetyl coenzyme A sodium can be used for the synthesis of phosphotransbutyrylase (PTB) and poly-3-hydroxybutyrate (PHB)[1][2].
IC 50
Microbial Metabolite
Purification Methods
Purification can be carried out by passage through a DEAE-cellulose formate column, then through a Dowex 50 (H+) column to remove Na ions, concentrated by lyophilisation and redissolved in H2O. It is commercially available as a solution of 0.05g/mL of H2O. The concentration of acetoacetylcoenzyme A is determined by the method of Stern et al. [J Biol Chem 221 15 1956]. It is stable at pH 7-7.5 for several hours at 0o (half-life ca 1-2hours). At room temperature it is hydrolysed in ca 1-2hours at pH 7-7.5. At pH 1.0/20o it is more stable than at neutrality. A solution of the trisodium salt (0.05g/mL H2O) adjusted to pH 5 with 2N NaOH can be stored frozen for several weeks. It is stable at pH 2-3/-17o for at least 6 months. [Hersch & Jencks J Biol Chem 242 3468 1967, Clikenbeard et al. J Biol Chem 250 3108 1975, Simon & Shemin J Am Chem Soc 75 2520 1953, Moffatt & Khorana 81 1265 1959, Salem et al. Biochem J 258 563 1989, Beilstein 26 III/IV 3668.]
References
[1] Thompson DK, et al. Purification and properties of an acetoacetyl coenzyme A-reacting phosphotransbutyrylase from Clostridium beijerinckii ("Clostridium butylicum") NRRL B593. Appl Environ Microbiol. 1990 Mar;56(3):607-13. DOI:10.1128/aem.56.3.607-613.1990
[2] Chohan SN, et al. Acetoacetyl coenzyme A reductase and polyhydroxybutyrate synthesis in rhizobium (Cicer) sp. Strain CC 1192. Appl Environ Microbiol. 1998 Aug;64(8):2859-63. DOI:10.1128/AEM.64.8.2859-2863.1998
ACETOACETYL COENZYME A SODIUM SALT Preparation Products And Raw materials
Raw materials
Preparation Products
ACETOACETYL COENZYME A SODIUM SALT Suppliers
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