ChemicalBook >> CAS DataBase List >>A-7 HYDROCHLORIDE
A-7 HYDROCHLORIDE
- CAS No.
- 79127-24-5
- Chemical Name:
- A-7 HYDROCHLORIDE
- Synonyms
- A-7 HYDROCHLORIDE;A7 hydrochloride,A 7 hydrochloride;1-[(10-Aminodec-1-yl)sulphamoyl]-5-chloronaphthalene;N-(10-AMINODECYL)-5-CHLORO-1-NAPHTHALENESULFONAMIDE HYDROCHLORIDE;N-(10-Aminodec-1-yl)-5-chloronaphthalene-1-sulfonamide hydrochloride;N-(10-AMinodecyl)-5-chloro-1-naphthalenesulfonaMide Monoydrochloride;N-(10-Aminodec-1-yl)-5-chloronaphthalene-1-sulphonamide hydrochloride
- CBNumber:
- CB0699211
- Molecular Formula:
- C20H29Cl2NO2S
- Molecular Weight:
- 418.42
- MDL Number:
- MFCD00269877
- MOL File:
- Mol file
Last updated:2023-09-04 15:51:00
| Melting point | 186-188°C |
|---|---|
| storage temp. | Store at RT |
| solubility | Soluble to 50mM in DMSO |
| form | White to off-white crystalline powder. |
| color | Pale Yellow to Yellow |
| CAS DataBase Reference | 79127-24-5 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| HS Code | 2935909099 | |||||||||
| NFPA 704 |
|
A-7 HYDROCHLORIDE price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Alfa Aesar | J62011 | A-7 hydrochloride | 79127-24-5 | 25mg | $233 | 2024-03-01 | Buy |
| Cayman Chemical | 16076 | A-7 (hydrochloride) ≥98% | 79127-24-5 | 5mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 16076 | A-7 (hydrochloride) ≥98% | 79127-24-5 | 10mg | $56 | 2024-03-01 | Buy |
| Cayman Chemical | 16076 | A-7 (hydrochloride) ≥98% | 79127-24-5 | 25mg | $72 | 2024-03-01 | Buy |
| Tocris | 0378 | A-7 hydrochloride | 79127-24-5 | 10 | $108 | 2021-12-16 | Buy |
A-7 HYDROCHLORIDE Chemical Properties,Uses,Production
Chemical Properties
White Crystalline Solid
Uses
Calmodulin antagonist
Uses
Calmodulin is a calcium-dependent protein that regulates the activity of a diverse array of enzymes, ion channels, and other proteins and thus has diverse roles in cell function. A-7 is an analog of the napthalenesulfonamide W-7 that has an acyl chain length of 10 carbons, rather than six. It is a potent cell-permeable antagonist of calmodulin that inhibits Ca2+/calmodulin cyclic nucleotide phosphodiesterase more potently than W-7 (IC50 = 3.2 and 26 μM, respectively).
Uses
Naphthalenesulfonamides
Biological Activity
Potent calmodulin antagonist (inhibits calmodulin-activated PDE activity with an IC 50 of 3 μ M).
storage
Room temperature
A-7 HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
A-7 HYDROCHLORIDE Suppliers
Global( 31)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55827 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44941 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24131 | 58 |
N-(10-AMINODECYL)-5-CHLORO-1-NAPHTHALENESULFONAMIDE HYDROCHLORIDE
A-7 HYDROCHLORIDE
N-(10-Aminodec-1-yl)-5-chloronaphthalene-1-sulphonamide hydrochloride
1-[(10-Aminodec-1-yl)sulphamoyl]-5-chloronaphthalene
N-(10-AMinodecyl)-5-chloro-1-naphthalenesulfonaMide Monoydrochloride
N-(10-Aminodec-1-yl)-5-chloronaphthalene-1-sulfonamide hydrochloride
A7 hydrochloride,A 7 hydrochloride
79127-24-5
C20H29ClN2O2SHCl
C20H30Cl2N2O2S
Amines
Aromatics
Intermediates & Fine Chemicals
Pharmaceuticals
Sulfur & Selenium Compounds
Calcium signaling
Protein Kinase Inhibitors and Activators