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Y-27632 DIHYDROCHLORIDE

Y-27632 DIHYDROCHLORIDE
Y-27632 DIHYDROCHLORIDE
CAS No.
146986-50-7
Chemical Name:
Y-27632 DIHYDROCHLORIDE
Synonyms
Y-27632;Y-276322HCl;ROCK INHIBITOR;Y-27632/Y27632;Y-27632 (2HCl),98%;Y-27632, free base;Y-27632 DIHYDROCHLORIDE;Y-27632, Free Base, >99%;4-[(1R)-1-Aminoethyl]-N-(4-pyridinyl)cyclohexanecarboxamide;4-[(1R)-1-Aminoethyl]-N-pyridin-4-ylcyclohexane-1-carboxamide
CBNumber:
CB0699488
Molecular Formula:
C14H23Cl2N3O
Formula Weight:
320.26
MOL File:
146986-50-7.mol

Y-27632 DIHYDROCHLORIDE Properties

storage temp. 
2-8°C
solubility 
H2O: 14 mg/mL
form 
solid
color 
white

SAFETY

Hazard Codes  Xn
Risk Statements  20/21/22
Safety Statements  36
WGK Germany  3

Y-27632 DIHYDROCHLORIDE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy

Y-27632 DIHYDROCHLORIDE Chemical Properties,Uses,Production

Definition

ChEBI: A monocarboxylic acid amide that is trans-[(1R)-1-aminoethyl]cyclohexanecarboxamide in which one of the nitrogens of the aminocarbony group is substituted by a pyridine nucleus. It has been shown to exhibit inhibitory acti ity against Rho-associated protein kinase (ROCK) enzyme.

Biological Activity

Selective inhibitor of the Rho-associated protein kinase p160ROCK. K i values are 0.14, 26, 25 and >250 μ M for p160ROCK, PKC, cAMP-dependent protein kinase and myosin light-chain kinase respectively. Also inhibits the protein kinase C-related protein kinase, PRK2 (IC 50 = 600nM). Smooth muscle relaxant and orally active in vivo . Increases survival rate of human embryonic stem (hES) cells undergoing cryopreservation.

Y-27632 DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products


Y-27632 DIHYDROCHLORIDE Suppliers

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146986-50-7(Y-27632 DIHYDROCHLORIDE)Related Search:


  • (+)-Trans-4-[1(r)-aminoethyl]-n-(4-pyridyl)cyclohexane-1-carboxamide
  • Y-27632 (2HCl),98%
  • (1R,4R)-4-((R)-1-aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamide
  • Y-27632, free base
  • 4-[(1R)-1-aminoethyl]-N-4-pyridinyl-trans-cyclohexanecarboxamide
  • 4-[(1R)-1-Aminoethyl]-N-pyridin-4-ylcyclohexane-1-carboxamide
  • (1R,4r)-4-((R)-1-aminoethyl)-N-(pyridin-4-yl)cyclohexane-1-carboxamide dihydrochloride
  • 4-[(1R)-1-Aminoethyl]-N-(4-pyridinyl)cyclohexanecarboxamide
  • ROCK INHIBITOR
  • (R)-(+)-TRANS-N-(4-PYRIDYL)-4-(1-AMINOETHYL)-CYCLOHEXANECARBOXAMIDE 2HCL
  • (R)-(+)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL)CYCLOHEXANECARBOXAMIDE DIHYDROCHLORIDE
  • (+)-R-TRANS-4-(AMINOETHYL)-N-(4-PYRIDYL)-CYCLOHEXANECARBOXAMIDE 2HCL H2O
  • Y-27632
  • Y-27632 DIHYDROCHLORIDE
  • TRANS-4-[(1R)-1-AMINOETHYL]-N-4-PYRIDINYLCYCLOHEXANECARBOXAMIDE DIHYDROCHLORIDE
  • Y-276322HCl
  • 4-[(1R)-1-Aminoethyl]-N-pyridin-4-ylcyclohexane-1-carboxamide dihydrochloride
  • (1R,4r)-4-((R)-1-aMinoethyl)-N-(pyridin-4-yl)cyclohexanecarboxaMide dihydrochloride
  • CyclohexanecarboxaMide,4-[(1R)-1-aMinoethyl]-N-4-pyridinyl-, trans-
  • Y-27632/Y27632
  • Y-27632, Free Base, >99%
  • 146986-50-7
  • BioChemical
  • Cell Biology
  • Cell Signaling and Neuroscience
  • Kinase/Phosphatase Biology
  • Rho Kinase (ROCK)
  • Serine/Threonine Kinase Inhibitors
  • -
  • Inhibitors
  • Protein Kinase
  • Signalling
  • Inhibitor
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