ChemicalBook >> CAS DataBase List >>THIP HYDROCHLORIDE
THIP HYDROCHLORIDE
- CAS No.
- 64603-91-4
- Chemical Name:
- THIP HYDROCHLORIDE
- Synonyms
- THPO;THIP;gaboxadol;Lu 02-030;Gaboxadolum;Gaboxadol-d4;Einecs 264-963-0;THIP HYDROCHLORIDE;Gaboxadolum [latin];4,5,6,7-Tetrahydroisoxazole(5,4-C)pyridin-3-ol
- CBNumber:
- CB0712787
- Molecular Formula:
- C6H8N2O2
- Molecular Weight:
- 140.14
- MDL Number:
- MFCD00242754
- MOL File:
- 64603-91-4.mol
Last updated:2024-03-26 17:16:27
| Melting point | 242-244° (dec) |
|---|---|
| Density | 1.36±0.1 g/cm3(Predicted) |
| storage temp. | Store at RT |
| solubility | ethanol: 0.91 mg/mL |
| pka | pKa (water, 25°): 4.44 ±0.03; 8.48 ±0.04 |
| form | solid |
| color | white |
| Stability | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months. |
| FDA UNII | K1M5RVL18S |
SAFETY
Risk and Safety Statements
| Safety Statements | 22-24/25 |
|---|---|
| WGK Germany | 3 |
| RTECS | NY3396800 |
THIP HYDROCHLORIDE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Tocris | 0807 | THIPhydrochloride ≥98%(HPLC) | 64603-91-4 | 50 | $162 | 2021-12-16 | Buy |
| Usbiological | 256926 | THIP hydrochloride | 64603-91-4 | 50mg | $403 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | BRS0001097 | GABOXADOL 95.00% | 64603-91-4 | 50MG | $685.21 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb528193 | THPO | 64603-91-4 | 10μg | $290.7 | 2021-12-16 | Buy |
| ChemScene | CS-0002507 | THIP 99.36% | 64603-91-4 | 25mg | $90 | 2021-12-16 | Buy |
THIP HYDROCHLORIDE Chemical Properties,Uses,Production
Description
Gaboxadol HCl (64603-91-4) is a GABA-A receptor agonist. Hypnotic agent.
Uses
GABAa agonist, GABAc antagonist
Definition
ChEBI: 4,5,6,7-Tetrahydroisoxazolo(5,4-c)pyridin-3-ol is an oxazole.
Biological Activity
Systemically active GABA A receptor agonist and GABA C receptor antagonist. Displays antinociceptive, anticonvulsant and sedative effects. Hypnotic agent that enhances delta activity within non-REM sleep in rats.
References
1) Meera et al. (2011), Molecular basis for the high THIP/gaboxadol sensitivity of extrasynaptic GABA(A) receptors; J. Neurophysiol., 106 2057
Synthesis of THIP HYDROCHLORIDE from Isoxazolo[5,4-c]pyridin-3(2H)-one, 4,5,6,7-tetrahydro-, hydrate (1:1)
THIP HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 86)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Dorne Chemical Technology co. LTD | +86-13583358881 +86-18560316533 | Ethan@dornechem.com | China | 294 | 58 |
| Shandong Hanjiang Chemical Co., Ltd | +86-0533-2066820 +8618369939125 | hanson@sdhanjiang.com | China | 1527 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
| Wuhan Monad Medicine Tech Co.,LTD | 02768782018 18771942761 | sales01@whmonad.com | CHINA | 992 | 58 |
| Xi'an MC Biotech, Co., Ltd. | 029-89275612 +8618991951683 | mcbio_sales@163.com | China | 2255 | 58 |
| Finetech Industry Limited | +86-27-87465837 +8618971612321 | info@finetechnology-ind.com | China | 9702 | 58 |
View Lastest Price from THIP HYDROCHLORIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-26 | THIP HYDROCHLORIDE
64603-91-4
|
US $1.00 / kg | 1kg | 99% | 100kg | Dorne Chemical Technology co. LTD | |
 |
2024-04-12 | THIP HYDROCHLORIDE
64603-91-4
|
US $0.00 / kg | 1kg | 0.99 | 10T | Shandong Hanjiang Chemical Co., Ltd | |
 |
2023-11-24 | THIP HYDROCHLORIDE
64603-91-4
|
US $7.00 / KG | 1KG | 98% | 1000KGS | Zhengzhou Anbu Chem Co.,Ltd |
-
- THIP HYDROCHLORIDE
64603-91-4
- US $1.00 / kg
- 99%
- Dorne Chemical Technology co. LTD
-
- THIP HYDROCHLORIDE
64603-91-4
- US $0.00 / kg
- 0.99
- Shandong Hanjiang Chemical Co., Ltd
-
- THIP HYDROCHLORIDE
64603-91-4
- US $7.00 / KG
- 98%
- Zhengzhou Anbu Chem Co.,Ltd
64603-91-4(THIP HYDROCHLORIDE)Related Search:
THIP HYDROCHLORIDE
4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3(2h)-onehydrate
4-c)pyridin-3(2h)-one,4,5,6,7-tetrahydro-isoxazolo(hydrate
gaboxadol
4,5,6,7-TETRAHYDROISOXAZOLO[5,4-C]PYRIDIN-3-OL
4,5,6,7-TETRAHYDROISOXAZOLO[5,4-C]PYRIDIN-3-OL HYDROCHLORIDE
4,5,6,7-Tetrahydroisoxazolo[5,4-c]pyridin-3(2H)-one
THIP
THPO
4,5,6,7-Tetrahydroisoxazole(5,4-C)pyridin-3-ol
Einecs 264-963-0
Gaboxadolum
Gaboxadolum [latin]
Isoxazolo(5,4-C)pyridin-3(2H)-one, 4,5,6,7-tetrahydro-
Lu 02-030
4,5,6,7-Tetrahydroisoxazolo[5,4-c]pyridin-3(2H)-one hydrochloride
Recombinant Mouse Thrombopoietin/Tpo/Thpo Protein, His Tag
Gaboxadol-d4
neurons,GABA Receptor,γ-Aminobutyric acid Receptor,IPSCs,THIP,Gamma-aminobutyric acid Receptor,inhibit,sleep disorders,Inhibitor
64603-91-4
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