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2-Amino-5-chloropyridine

CAS No.
1072-98-6
Chemical Name:
2-Amino-5-chloropyridine
Synonyms
5-CHLOROPYRIDIN-2-AMINE;5-CHLORO-2-AMINOPYRIDINE;AKOS 91155;TIMTEC-BB SBB000059;5-Chlor-2-pyridylamin;5-CHLORO-A-PYRIDYLAMINE;5-CHLORO-2-PYRIDYLAMINE;5-CHLORO-2-PYRIDINAMINE;2-Amino-5-Cloropyridine;5-Chloro-a-aminopyridine
CBNumber:
CB0736206
Molecular Formula:
C5H5ClN2
Molecular Weight:
128.56
MDL Number:
MFCD00006324
MOL File:
1072-98-6.mol
MSDS File:
SDS
Last updated:2024-01-22 16:43:48

2-Amino-5-chloropyridine Properties

Melting point 135-138 °C (lit.)
Boiling point 127-128 °C/11 mmHg (lit.)
Density 1.2417 (rough estimate)
refractive index 1.5110 (estimate)
Flash point 160 °C
storage temp. 2-8°C
solubility 1.0g/l
form Crystalline Powder
pka 4.67±0.13(Predicted)
color Beige to beige-brown
Water Solubility 1 g/L (20 ºC)
BRN 108735
InChIKey MAXBVGJEFDMHNV-UHFFFAOYSA-N
CAS DataBase Reference 1072-98-6(CAS DataBase Reference)
NIST Chemistry Reference 2-Amino-5-chloropyridine(1072-98-6)
EPA Substance Registry System 2-Amino-5-chloropyridine (1072-98-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H302-H312-H332-H335
Precautionary statements  P261-P264-P270-P271-P280-P301+P312+P330-P302+P352+P312+P362+P364-P304+P340+P312-P305+P351+P338+P337+P313-P501-P280h-P305+P351+P338
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38
Safety Statements  22-24/25-37/39-26-36
WGK Germany  3
Hazard Note  Harmful
HazardClass  IRRITANT
HS Code  29333999
NFPA 704
1
1 0

2-Amino-5-chloropyridine price More Price(42)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A46803 2-Amino-5-chloropyridine 98% 1072-98-6 25g $25.3 2023-06-20 Buy
Sigma-Aldrich BP813 2-Amino-5-chloropyridine British Pharmacopoeia (BP) Reference Standard 1072-98-6 25MG $237 2023-06-20 Buy
Sigma-Aldrich A46803 2-Amino-5-chloropyridine 98% 1072-98-6 100g $77.3 2023-06-20 Buy
TCI Chemical A0837 2-Amino-5-chloropyridine >98.0%(GC)(T) 1072-98-6 25g $26 2023-06-20 Buy
TCI Chemical A0837 2-Amino-5-chloropyridine >98.0%(GC)(T) 1072-98-6 100g $91 2023-06-20 Buy
Product number Packaging Price Buy
A46803 25g $25.3 Buy
BP813 25MG $237 Buy
A46803 100g $77.3 Buy
A0837 25g $26 Buy
A0837 100g $91 Buy

2-Amino-5-chloropyridine Chemical Properties,Uses,Production

Chemical Properties

beige to beige-brown crystalline powder

Uses

5-Chloro-2-pyridinamine is a useful synthetic intermediate. It can be used to synthesize zopiclone (Z700500) which is a cyclopyrrolone member of a family of non-benzodiazepine GABAA receptor agonists.

Synthesis Reference(s)

The Journal of Organic Chemistry, 41, p. 93, 1976 DOI: 10.1021/jo00863a020

Purification Methods

Recrystallise this base from pet ether. It sublimes at 50o/0.5mm. [Beilstein 22 II 332, 22/8 V 541.]

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View Lastest Price from 2-Amino-5-chloropyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Amino-5-chloropyridine pictures 2024-01-22 2-Amino-5-chloropyridine
1072-98-6
US $8.00-0.80 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
2-Amino-5-chloropyridine pictures 2023-11-01 2-Amino-5-chloropyridine
1072-98-6
US $0.00-0.00 / kg 0.10000000149011612kg 99.0%min 200kg Hangzhou ICH Biofarm Co., Ltd
2-Amino-5-chloropyridine pictures 2023-10-18 2-Amino-5-chloropyridine
1072-98-6
US $9.18 / KG 10KG 99% 100kg Wuhan Han Sheng New Material Technology Co.,Ltd
2-Amino-5-chloropyridine  5-Chloro-2-pyridineamine 5-Chloro-a-aminopyridine 2-Amino-5-chloropyridine ,98% 2-Amino-5-chloropyridine 2-AMINO-5-CHLOROPYRIDINE 5-CHLORO-PYRIDIN-2-YLAMINE 2-Amino-5-chlorophridine 2-AMINO-5-CHLOROPYRIDINE FOR SYNTHESIS 2-aMino -5-chlorine pyridine TIMTEC-BB SBB000059 2-Pyridinamine, 5-chloro- Pyridine, 2-amino-5-chloro- AMINO(2-)-5-CHLOROPYRIDINE AKOS 91155 5-CHLOROPYRIDIN-2-YLAMINE 5-CHLORO-A-PYRIDYLAMINE 5-CHLORO-2-PYRIDYLAMINE 5-CHLORO-2-PYRIDINAMINE 2-AMINO-5-CHLIROPYRIDINE 2-Pyridinamine,5-chloro-(9CI) 2-Amino-5-Chloro Pyriine 2-AMINO-5-CHLOROPYRIDINE 99% 2-Amino-5-chloropyridine HPLC 99.5%Individual impurity = NMT 0.10 % 2-Amino-5-chloropyridine > 2-Bromo-3-Chloro-7-(Trifluoromethyl)Pyridine 2-Amino-5-chloropyridine ISO 9001:2015 REACH Edoxaban Impurity 37 / Zopiclone Impurity 1 5-Chlor-2-pyridylamin 5-CHLOROPYRIDIN-2-AMINE 5-CHLORO-2-AMINOPYRIDINE 2-Amino-5-Cloropyridine 2-Amino-5-chloropyridine 1072-98-6 C5H5CIN2 C5H5N2Cl Heterocyclic Building Blocks Halogenated Heterocycles Building Blocks Halopyridines Chloropyridines Pyridines FINE Chemical & INTERMEDIATES Amines blocks PYRIDINE Nitrogen cyclic compounds Heterocycle-Pyridine series amine| alkyl chloride Pyridines derivates Chloropyridines Halopyridines C5Heterocyclic Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Pyridines, Pyrimidines, Purines and Pteredines Bromides Pyridines bc0001