ChemicalBook >> CAS DataBase List >>Indole-5-carboxylic acid

Indole-5-carboxylic acid

CAS No.
1670-81-1
Chemical Name:
Indole-5-carboxylic acid
Synonyms
1H-INDOLE-5-CARBOXYLIC ACID;JACS-1670-81-1;5-CARBOXYINDOLE;5-Carboxy-1H-indole;RARECHEM AL BO 0206;TIMTEC-BB SBB003951;Indolecarboxylicacid,5-;5-INDOLECARBOXYLIC ACID;INDOLE-5-CARBOXYLIC ACID;INDOLE-5-CARBOXYLIC AICD
CBNumber:
CB0736428
Molecular Formula:
C9H7NO2
Molecular Weight:
161.16
MDL Number:
MFCD00005678
MOL File:
1670-81-1.mol
MSDS File:
SDS
Last updated:2023-05-04 17:34:34

Indole-5-carboxylic acid Properties

Melting point 211-213 °C (lit.)
Boiling point 287.44°C (rough estimate)
Density 1.2480 (rough estimate)
refractive index 1.5050 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Soluble in ethanol (50 mg/ml), dimethyl sulfoxide and methanol.
pka 4.40±0.30(Predicted)
form Powder
color Light beige to yellow
BRN 124391
InChIKey IENZCGNHSIMFJE-UHFFFAOYSA-N
CAS DataBase Reference 1670-81-1(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xn,Xi
Risk Statements  36/37/38-21/22
Safety Statements  22-24/25-36/37/39-26
WGK Germany  3
HazardClass  IRRITANT
HS Code  29339990
NFPA 704
0
2 0

Indole-5-carboxylic acid price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical I0029 Indole-5-carboxylic Acid >98.0%(GC)(T) 1670-81-1 1g $42 2024-03-01 Buy
TCI Chemical I0029 Indole-5-carboxylic Acid >98.0%(GC)(T) 1670-81-1 5g $81 2024-03-01 Buy
Alfa Aesar A18627 Indole-5-carboxylic acid, 98% 1670-81-1 1g $40.65 2024-03-01 Buy
Alfa Aesar A18627 Indole-5-carboxylic acid, 98% 1670-81-1 5g $133 2024-03-01 Buy
Alfa Aesar A18627 Indole-5-carboxylic acid, 98% 1670-81-1 25g $493.65 2024-03-01 Buy
Product number Packaging Price Buy
I0029 1g $42 Buy
I0029 5g $81 Buy
A18627 1g $40.65 Buy
A18627 5g $133 Buy
A18627 25g $493.65 Buy

Indole-5-carboxylic acid Chemical Properties,Uses,Production

Chemical Properties

light beige to yellow powder

Uses

Indole-5-carboxylic acid is the suitable reagent used to study the intramolecular excited state proton transfer in indole-2-carboxylic acid and indole-5-carboxylic acid in various solvents in acidic, basic, and neutral media by steady state and time resolved fluorescence spectroscopy. It may be used in the electrochemical synthesis of poly(indole-5-carboxylic acid) (PICA) films.

Uses

Reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles, as potential anticancer immunomodulators 1 Reactant for preparation of indolyl-quinolines via metal- and solvent-free autoxidative coupling reaction 2 Reactant for preparation of anthranilic acids using bromamine-B oxidant and palladium chloride catalyst 3 Reactant for synthesis of indirubin derivatives 4 Reactant for preparation of amide conjugates with ketoprofen, as inhibitors of Gli1-mediated transcription in Hedgehog pathway 5 Reactant for preparation of piperazine-bisamide analogs as human growth hormone secretagogue receptor antagonists for treatment of obesity.

Uses

Indole-5-carboxylic acid is the suitable reagent used to study the intermolecular excited state proton transfer in indole-2-carboxylic acid and indole-5-carboxylic acid in various solvents in acidic, basic, and neutral media by steady state and time resolved fluorescence spectroscopy. It may be used in the electrochemical synthesis of poly(indole-5-carboxylic acid) (PICA) films. Also used as reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles, as potential anticancer immunomodulators, synthesis of indirubin derivatives and amide conjugates with ketoprofen, as inhibitors of Gli1-mediated transcription in Hedgehog pathway.

Definition

ChEBI: Indole-5-carboxylic acid is an indolecarboxylic acid in which the carboxy group is the only substituent and is located at position 5. It has a role as a plant metabolite.

General Description

Indole-5-carboxylic acid is an indole derivative. On electropolymerization, it affords electroactive polymer film of poly(indole-5-carboxylic-acid). Different concentrations of indole-5-carboxylic acid in sulfuric acid solution has been investigated for the preventive action against mild steel corrosion. On electropolymerization it affords a trimeric product. Characterization studies of the trimeric product by 1H NMR and various one- and two-dimensional NMR techniques have been reported.

10075-50-0
124-38-9
1670-81-1
Synthesis of Indole-5-carboxylic acid from 5-Bromoindole and Carbon dioxide
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View Lastest Price from Indole-5-carboxylic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Indole-5-carboxylic acid pictures 2023-04-12 Indole-5-carboxylic acid
1670-81-1
US $65.00 / kg 1kg 99% 5000 tons Hebei Duling International Trade Co. LTD
Indole-5-carboxylic acid pictures 2021-08-12 Indole-5-carboxylic acid
1670-81-1
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
Indole-5-carboxylic acid   in stock Factory pictures 2020-06-02 Indole-5-carboxylic acid in stock Factory
1670-81-1
US $1.00 / KG 1KG TOP 3 Factory in China Top 3 production capacity Factory Chemwill Asia Co.,Ltd.
TIMTEC-BB SBB003951 RARECHEM AL BO 0206 5-CARBOXYINDOLE 5-INDOLECARBOXYLIC ACID Indolecarboxylicacid,5- INDOLE-5-CARBOXYLIC ACID Indole-5-carboxylic acid ,98% 5-Carboxy-1H-indole INDOLE-5-CARBOXYLIC ACID (I5CA) INDOLE-5-CARBOXYLIC AICD 1H-indole-5-carboxylic acid(SALTDATA: FREE) Indole-5-carboxylic acid, 98% 5GR INDOLE-5-CARBOXYLIC ACID FOR SYNTHESIS JACS-1670-81-1 Indole-5-carboxylic acid in stock Factory Indole-5-carboxylicAcid> 1H-INDOLE-5-CARBOXYLIC ACID 1H-Indole-5-carboxylic acid (9CI, ACI) (R)-5-BROMO-3-((METHYLPYRROLIDIN-2-YL)METHYL)-1H-INDOLE 1670-81-1 Simple Indoles Indoles Building Blocks Heterocyclic Building Blocks Heterocycle-Indole series Simple Indoles Building Blocks Heterocyclic Building Blocks blocks Carboxes IndolesOxindoles Indole/indoline/oxindole Indole and Indoline Indoles and derivatives Indole Indoles