ChemicalBook
Chinese Japanese Germany

Baicalein

Baicalein
Baicalein
CAS No.
491-67-8
Chemical Name:
Baicalein
Synonyms
Noroxylin;Baicelein;Baicalein;Baicaleine;Baicalein 98%;Baicalein std.;Bupleurum distillates;5,6,7-TRIHYDROXYFLAVONE;BAICALEIN, 98+% BY HPLC;Nano Liposomal Baicalein
CBNumber:
CB0738154
Molecular Formula:
C15H10O5
Formula Weight:
270.24
MOL File:
491-67-8.mol

Baicalein Properties

Melting point:
256-271 °C(lit.)
Boiling point:
373.35°C (rough estimate)
Density 
1.3280 (rough estimate)
refractive index 
1.5000 (estimate)
storage temp. 
2-8°C
Merck 
14,942
BRN 
272683
CAS DataBase Reference
491-67-8(CAS DataBase Reference)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-20/21/22
Safety Statements  26-36
WGK Germany  3
RTECS  DJ3100898
Hazard Note  Irritant
HS Code  29329990
Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Baicalein price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 465119 Baicalein 98% 491-67-8 100mg $39.6 2018-11-13 Buy
Sigma-Aldrich 196322 Baicalein 491-67-8 10mg $130 2018-11-20 Buy
TCI Chemical T2721 Baicalein >98.0%(T) 491-67-8 1g $126 2018-11-22 Buy
TCI Chemical T2721 Baicalein >98.0%(T) 491-67-8 5g $407 2018-11-22 Buy
Alfa Aesar L14185 5,6,7-Trihydroxyflavone, 97% 491-67-8 100mg $35.3 2018-11-13 Buy

Baicalein Chemical Properties,Uses,Production

Chemical Properties

Yellow Crystalline Solid

Uses

antiviral (HIV)

Uses

An inhibitor of 12-lipoxygenase, leukotriene biosynthesis and release of lysosomal enzymes. It also inhibits cellular Ca2+ uptake and mobilization and adjuvant-induced arthritis. Baicalein is the fl avonoid component of Nepalese and Sino-Japanese crude drugs.

Uses

inhibitor of lipoxidase and leukotriene biosynthesis

Uses

An inhibitor of Ca2+ uptake, 5-LO, and 12-LO

Definition

ChEBI: A trihydroxyflavone with the hydroxy groups at positions C-5, -6 and -7.

Uses

Baicalein is a flavonoid originally isolated from the roots of Scutellaria baicalensis Georgi. Several different functions of baicalein have been reported. Platelet 12-lipoxygenase is inhibited by baicalein with an ID50 value of 0.12 μM, with minimal inhibition of platelet cyclooxygenase-1 (IC50 = 0.83 mM). Baicalein inhibits lipid peroxidation, as assessed by production of TBARS, with an IC50 value of 5 μM. In addition to these effects, baicalein may play a role in apoptosis, as the compound inhibits cell growth of three human hepatocellular carcinoma cell lines with IC50 values ranging from 17-70 μg/ml.

Biological Activity

Inhibitor of 5- and platelet 12-lipoxygenases (IC 50 values are 9.5 and 0.12 mM respectively). Also inhibits Raf-mediated MEK-1 phosphorylation in C6 rat glioma cells and induces G1 and G2 cell cycle arrest by decreasing cdk1, cdk2, cyclin D2 and cyclin A expression. Anti-inflammatory in vivo .

Baicalein Preparation Products And Raw materials

Raw materials

Preparation Products


Baicalein Suppliers

Global( 255)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 sales@capotchem.com China 19957 60
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3218 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 22080 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20795 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32764 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 10010 58
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3624 58
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)
+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing) sh@meryer.com China 40399 62
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、802、803、804 Mobile:18930552037
86-21-50328109 3bsc@sina.com China 15940 69

View Lastest Price from Baicalein manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-08-20 Baicalein
491-67-8
US $1.00 / KG 1G 98% 100KG
2018-08-20 Baicalein
491-67-8
US $2.00 / KG 1KG 98% 1 ton

491-67-8(Baicalein)Related Search:


Copyright 2017 © ChemicalBook. All rights reserved