ChemicalBook >> CAS DataBase List >>L-Canavanine sulfate
L-Canavanine sulfate
- CAS No.
- 2219-31-0
- Chemical Name:
- L-Canavanine sulfate
- Synonyms
- L-CANAVANINE SULPHATE;CANAVANINE SULFATE;canavanine sulphate;L-CANAVANINE SULFATE;CANAVANINE SULFATE, L-;CANAVANINE SULFATE, L-(P);L-Canavanine Sulfate L-CANAVANINE SULFATE SALT;CANAVANINE SULFATE, L-(RG);L-CANAVANINE SULFATE HYDRATE
- CBNumber:
- CB0746906
- Molecular Formula:
- C5H14N4O7S
- Molecular Weight:
- 274.25
- MDL Number:
- MFCD00012618
- MOL File:
- 2219-31-0.mol
- MSDS File:
- SDS
Last updated:2023-05-18 11:31:02
| Melting point | 160-165 °C (dec.) |
|---|---|
| storage temp. | 2-8°C |
| solubility | H2O: 100 mg/mL |
| form | powder |
| color | white |
| BRN | 6121291 |
| Stability | Hygroscopic |
| CAS DataBase Reference | 2219-31-0(CAS DataBase Reference) |
| FDA UNII | PN00Q697SG |
| EPA Substance Registry System | L-Canavanine sulfate (2219-31-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H332-H312-H302 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P280-P302+P352-P312-P322-P363-P501-P261-P271-P304+P340-P312 |
| Hazard Codes | Xn |
| Risk Statements | 20/21/22-36/37/38 |
| Safety Statements | 36-26 |
| RIDADR | 2811 |
| WGK Germany | 3 |
| HS Code | 2925290090 |
L-Canavanine sulfate price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C9758 | L-Canavanine sulfate salt ≥99% (TLC), powder | 2219-31-0 | 1g | $242 | 2024-03-01 | Buy |
| Sigma-Aldrich | C9758 | L-Canavanine sulfate salt ≥99% (TLC), powder | 2219-31-0 | 5g | $919 | 2024-03-01 | Buy |
| TCI Chemical | C0018 | L-Canavanine Sulfate Hydrate >97.0%(T) | 2219-31-0 | 100mg | $107 | 2024-03-01 | Buy |
| Sigma-Aldrich | C9758 | L-Canavanine sulfate salt ≥99% (TLC), powder | 2219-31-0 | 100mg | $56.1 | 2024-03-01 | Buy |
| Sigma-Aldrich | C9758 | L-Canavanine sulfate salt ≥99% (TLC), powder | 2219-31-0 | 250mg | $71.4 | 2024-03-01 | Buy |
L-Canavanine sulfate Chemical Properties,Uses,Production
Uses
A Nitric Oxide Synthase inhibitor
Uses
Canavanine sulfate salt has been used:
- as a translation inhibitor in yeast translation studies
- as a component of synthetic complete (SC) drop-out medium for screening yeast
- for screening Saccharomyces cerevisiae in canavanine mutation frequency assay
Definition
ChEBI: An organic sulfate salt obtained by combining L-canavanine with one molar equivalent of sulfuric acid.
General Description
Canavanine is a homolog of arginine and a non-protein amino acid. It is present in plants like alfalfa, cloves, beans onions and sprouts. Canavanine is synthesized from L-canavaninosuccinic acid and the biosynthetic pathway was first elucidated in jack bean plant.
Biological Activity
NO synthase inhibitor.
Biochem/physiol Actions
Canavanine is a naturally occurring?L-amino acid that competes and interferes with?L-arginine-utilizing enzymes due to its structural similarity with this?L-amino acid. It is a selective inhibitor of inducible nitric oxide synthase (iNOS). It acts as a substrate for arginyl tRNA and is incorporated during protein synthesis leading to aberrant canavanyl proteins. Supplementation with canavanine worsens the alfalfa induced Systemic lupus erythematosus (SLE) like syndrome and its incorporation with endosome and proteasome disrupts the antigen processing.
Purification Methods
Recrystallise the sulfate by dissolving (~1g) in H2O (10mL), and adding with stirring 0.5 to 1.0 volumes of 95% EtOH whereby crystals separate. These are collected, washed with Me2CO/EtOH (1:1) and dried over P2O5 in a vacuum. [Hunt & Thompson Biochemical Preparations 13 416 1971, Feacon & Bell Biochem J 59 221 1955, Beilstein 4 III 1636, 4 IV 3188.]
L-Canavanine sulfate Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 148)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9641 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23556 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29474 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
View Lastest Price from L-Canavanine sulfate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-08-12 | L-CANAVANINE SULFATE
2219-31-0
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2019-07-06 | L-CANAVANINE SULFATE
2219-31-0
|
US $1.00 / kg | 1g | 99% | 100KG | Career Henan Chemical Co |
-
- L-CANAVANINE SULFATE
2219-31-0
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- L-CANAVANINE SULFATE
2219-31-0
- US $1.00 / kg
- 99%
- Career Henan Chemical Co
2219-31-0(L-Canavanine sulfate)Related Search:
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L-Canavanine sulfate
L-CANALINE BASE
Ammonium sulfite monohydrate
1of4
canavanine sulphate
L-canavanine sulfate crystalline
L-Canavanine Sulfate, Canavalia ensiformis
l-α-amino-γ-(guanidinooxy)butyric acid sulfate salt
CANAVANINE SULFATE, L-(RG)
L-CANAVANINE SULFATE HYDRATE
L-CANAVANINE SULFATE
CANAVANINE SULFATE
CANAVANINE SULFATE, L-
o-[(aminoiminomethyl)amino]-l-homoserinsulfate(1:1)
L-Canavanine sulfate L-Canavanine sulfate
2-AMino-4-(guanidinooxy)butyric Acid Sulfate
O-[(AMinoiMinoMethyl)aMino]-L-hoMoserine Sulfate
CANAVANINE SULFATE, L-(P)
L-HoMoserine, O-[(aMinoiMinoMethyl)aMino]-, sulfate (1:1)
O-{[amino(imino)methyl]amino}homoserine sulfate (salt)
L-Canavanine Sulfate
L-2-AMINO-4-(GUANIDIOOXY)BUTYRIC ACID SULFATE
L-ALPHA-AMINO-GAMMA-(GUANIDINOOXYL)-N-BUTYRIC ACID SULFATE
L-ALPHA-AMINO-GAMMA (GUANIDINOOXY)-N-BUTYRIC ACID SULFATE
L-ALPHA-AMINO-GAMMA-[GUANIDINOOXY]-N-BUTYRIC ACID SULFATE SALT
L-CANAVANINE SULFATE SALT
L-Canavanine sulfate USP/EP/BP
L-Canavanine Sulfate Hydrate>
(S)-2-Amino-4-(guanidinooxy)butanoic acid compound with sulfuric acid (1:1)
L-CANAVANINE SULPHATE
2219-31-0
C5H14N4O7S
C5H12O3N3
C5H12N4OH2SO4
C5H12N4O3H2SO4
C5H12N4O3xH2SO4
C5H12N4O3H2SO4xH2O
C5H12N4O3H2O4S
Biochemicals and Reagents
BioChemical
L to O
Peptide Synthesis
Others
Nitric Oxide Synthase (iNOS)
Specialty Synthesis
Unnatural Amino Acid Derivatives
Enzyme Inhibitors
Enzyme Inhibitors by Enzyme
Enzymes, Inhibitors, and Substrates
Hydroxylamines (N-Substituted)
Hydroxylamines
Hydroxylamines (O-Substituted)
amino acid derivative
Amino Acids & Derivatives
Amino Acids
Inhibitors
Nitric Oxide Reagents
Hydroxylamines (N-Substituted)
Hydroxylamines (O-Substituted)
non-Proteinorganic Amino Acids
Amino Acids
Biochemistry