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Tetraisopropyl methylenediphosphonate

CAS No.
1660-95-3
Chemical Name:
Tetraisopropyl methylenediphosphonate
Synonyms
Medronic Acid EP Impurity B;Medronic acid impurity B CRS;Tetraisopropyl Methylenediphonate;Bis(diisopropoxyphosphinyl)methane;Tetrakis(1-methylethyl) Methylenedi;tetra-i-Propylmethylenediphosphonate;TETRAISOPROPYL METHYLENEDIPHOSPHONATE;TETRAISOPROPYL(METHYLENE)BISPHOSPHONATE;TetraisopropylMethylenediphosphonate>Tetra-isopropyl methyldiphosphate ester
CBNumber:
CB0747453
Molecular Formula:
C13H30O6P2
Molecular Weight:
344.32
MDL Number:
MFCD00015021
MOL File:
1660-95-3.mol
MSDS File:
SDS
Last updated:2023-08-15 19:02:16

Tetraisopropyl methylenediphosphonate Properties

Boiling point 155 °C/0.5 mmHg (lit.)
Density 1.08 g/mL at 25 °C (lit.)
vapor pressure 0.017Pa at 20℃
refractive index n20/D 1.431(lit.)
Flash point 320 °F
storage temp. -20°C
solubility Chloroform (Slightly), Methanol (Slightly)
color Clear Colourless to Yellow
Specific Gravity 1.080
Water Solubility Insoluble in water.
BRN 1080180
InChIKey FKHXXJRKGVDPQP-UHFFFAOYSA-N
LogP 1.3 at 20℃
CAS DataBase Reference 1660-95-3(CAS DataBase Reference)
FDA UNII K46Y5V9U61
NIST Chemistry Reference Tetraisopropyl methylenediphosphonate(1660-95-3)
EPA Substance Registry System Phosphonic acid, methylenebis-, tetrakis(1-methylethyl) ester (1660-95-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS05
Signal word  Danger
Hazard statements  H318
Precautionary statements  P280-P305+P351+P338+P310
Hazard Codes  Xi
Risk Statements  41
Safety Statements  26-36-39
WGK Germany  3
TSCA  Yes
HS Code  29319090
NFPA 704
0
2 0

Tetraisopropyl methylenediphosphonate price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich Y0001106 Medronic acid impurity B European Pharmacopoeia (EP) Reference Standard 1660-95-3 y0001106 $91.8 2024-03-01 Buy
Sigma-Aldrich 426431 Tetraisopropyl methylenediphosphonate 97% 1660-95-3 25ml $62.8 2024-03-01 Buy
TCI Chemical M1319 Tetraisopropyl Methylenediphosphonate >97.0%(GC) 1660-95-3 25g $84 2024-03-01 Buy
Alfa Aesar A13484 Tetraisopropyl methylenediphosphonate, 98% 1660-95-3 10g $50.65 2024-03-01 Buy
Alfa Aesar A13484 Tetraisopropyl methylenediphosphonate, 98% 1660-95-3 50g $198 2024-03-01 Buy
Product number Packaging Price Buy
Y0001106 y0001106 $91.8 Buy
426431 25ml $62.8 Buy
M1319 25g $84 Buy
A13484 10g $50.65 Buy
A13484 50g $198 Buy

Tetraisopropyl methylenediphosphonate Chemical Properties,Uses,Production

Chemical Properties

Clear colorless to slightly yellow liquid

Uses

Tetraisopropyl methylenediphosphonate [T(iPr)MDP] forms a synergistic mixture with hydrogen dicarbollylcobaltate in nitrobenzene which was used in the extraction of europium and americium.
It may be used in the synthesis of the following:

  • tetraisopropyl ethenylidenebisphosphonate.
  • tetraisopropyl 4-acetylthiobutane-1,1-diphosphonate
  • tetraisopropyl 2-(3,5-bis(bromomethyl)phenyl)ethane-1,1-diphosphonate

Uses

Tetraisopropyl Methylenediphosphonate is used in the preparation of E2-bisphosphonate conjugates as potential anti-osteoporosis agents. Also used in the preparation of AZT 5’-Triphosphate compounds which display inhibitory effects on HIV-1 reverse transcrpitase.

General Description

Tetraisopropyl methylenediphosphonate (IPCP) is a tetraisopropyl ester of methylenediphosphonic acid. It is an electroneutral ligand, reported to be synthesized from triisopropyl phosphate. Powder electron paramagnetic resonance (EPR) studies of tris complexes of Cu(II) complexes with IPCP has been analyzed.

Global( 229)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mojin Biotechnology Co., Ltd
+8613288715578 sales@hbmojin.com China 12456 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 15928 58
Henan Tianfu Chemical Co.,Ltd.
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career henan chemical co
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Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503282 alice@crovellbio.com China 8823 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63711 58
Shanghai Yingrui Biopharma Co.,Ltd
21-33585366 export01@shyrchem.com CHINA 1320 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 47465 58

View Lastest Price from Tetraisopropyl methylenediphosphonate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Tetraisopropyl methylenediphosphonate pictures 2023-08-15 Tetraisopropyl methylenediphosphonate
1660-95-3
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
Tetraisopropyl methylenediphosphonate pictures 2022-12-19 Tetraisopropyl methylenediphosphonate
1660-95-3
US $0.00-0.00 / KG 1KG 99% 20 mt Hebei Guanlang Biotechnology Co., Ltd.
Tetraisopropyl methylenediphosphonate pictures 2022-12-19 Tetraisopropyl methylenediphosphonate
1660-95-3
US $0.00-0.00 / KG 1KG 99% 20 mt Hebei Guanlang Biotechnology Co., Ltd.
Tetraisopropyl methylenediphosphonate,98% Tetraisopropyl methylenediphosphonatedisc 6/01 Tetraisopropyl Methylenediphosphonate(for DisodiuM clodronate) Tetraisopropyl methylenediphosphonate 97% Bis(propan-2-yl) {[bis(propan-2-yloxy)-phosphoryl]methyl}phosphonate METHYLENEDIPHOSPHONIC ACID TETRAISOPROPYL ESTER TETRAISOPROPYL(METHYLENE)BISPHOSPHONATE TETRAISOPROPYL METHYLENEDIPHOSPHONATE Phosphonic acid, methylenebis-, tetrakis(1-methylethyl) ester Phosphonic acid, methylenedi-, tetraisopropyl ester phosphonicacid,methylenebis-,tetrakis(1-methylethyl)ester tetra-i-Propylmethylenediphosphonate Methanediphosphonic acid tetraisopropyl ester Tetra isopropyl methylene diphospshonate METHYLENEBIS-PHOSPHONICACID,TETRAKIS(1-METHYLETHYL)ESTER METHYLENEPHOSPHONIC ACID TETRAISOPROPYL ESTER Tetraisopropyl(methylene)bisphosphonate, 98 % 2-[Di(propan-2-yloxy)phosphorylmethyl-propan-2-yloxyphosphoryl]oxypropane Bis(diisopropoxyphosphinyl)methane Tetraisopropyl Methylenediphonate TetraisopropylMethylenediphosphonate> Medronic acid impurity B CRS Tetrakis(1-methylethyl) Methylenedi Phosphonic acid, P,P'-methylenebis-, P,P,P',P'-tetrakis(1-methylethyl) ester Tetra-isopropyl methyldiphosphate ester Medronic Acid EP Impurity B 1660-95-3 CH2POOCHCH3222 C13H30O6P2 Organic Building Blocks Phosphonates/Phosphinates Phosphorus Compounds Building Blocks Organic Building Blocks Phosphonates/Phosphinates Phosphorus Compounds