ChemicalBook >> CAS DataBase List >>ETHYL 6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE

ETHYL 6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE

ETHYL 6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE structure

CAS No.: 33458-26-3

Chemical Name:: ETHYL 6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE

Synonyms: 5118-36-5;EU-006731;NSC643910;SBB016167;NCI60_014903;Oprea1_330764;A0951/0044480;AURORA KA-3499;Maybridge1_006365;BUTTPARK 61\40-96

CBNumber:: CB0767606

Molecular Formula:: C14H16N2O2S

Molecular Weight:: 276.35

MDL Number:: MFCD00188414

MOL File:: 33458-26-3.mol

Last updated:2023-04-27 16:27:43

Request For Quotation

ETHYL 6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE Properties

Melting point	180
Boiling point	390.5±52.0 °C(Predicted)
Density	1.25±0.1 g/cm3(Predicted)
pka	11.33±0.70(Predicted)
InChIKey	QMFBVGUFEGVPNG-UHFFFAOYSA-N

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS06
Signal word	Danger
Hazard statements	H301-H319-H335-H312+H332-H315
Precautionary statements	P280-P301+P310-P362+P364
Hazard Codes	Xi
HazardClass	IRRITANT
HS Code	2933599590

ETHYL 6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE price More Price(8)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	S170372	6-ME-4-PH-2-THIOXO-1,2,3,4-TETRAHYDRO-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER AldrichCPR	33458-26-3	50MG	$110	2024-03-01	Buy
Matrix Scientific	061399	Ethyl 6-methyl-4-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate	33458-26-3	500mg	$315	2021-12-16	Buy
American Custom Chemicals Corporation	CHM0029794	ETHYL 6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE 95.00%	33458-26-3	1G	$624.07	2021-12-16	Buy
American Custom Chemicals Corporation	CHM0029794	ETHYL 6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE 95.00%	33458-26-3	10G	$1176.29	2021-12-16	Buy
Atlantic Research Chemicals	ES01233	Ethyl6-Methyl-4-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate 95%	33458-26-3	1gm:	$60.09	2021-12-16	Buy

Product number	Packaging	Price	Buy
S170372	50MG	$110	Buy
061399	500mg	$315	Buy
CHM0029794	1G	$624.07	Buy
CHM0029794	10G	$1176.29	Buy
ES01233	1gm:	$60.09	Buy

ETHYL 6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE Chemical Properties,Uses,Production

Uses

ETHYL 6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical and pharmaceutical production process middle.

Synthesis

In a 10-mL round-bottom flask equipped with a condenser, a mixture of the aromatic aldehyde (1 mmol), ethyl acetoacetate (1 mmol), urea or thiourea (1.5 mmol) and [Dsbim]Cl (0.0376 g, 10 mol%) was stirred at 80 °C, and the resulting mixture was kept under continuous stirring for lengths of time as specified in Table 3, with the progress of the reaction was followed by TLC. After completion of the reaction, the mixture was cooled to room temperature, and 3 mL of water was added. The ionic liquid was dissolved in water and filtered for separation of the crude product. The separated product was washed twice with water (2 9 3 mL). For recycling the catalysts, after the solid products were thoroughly washed with water, the water containing the ionic liquid (IL is soluble in water) was evaporated under reduced pressure, and the ionic liquid was recovered and reused. The solid product was purified by a recrystallization procedure in ethanol. All of the desired product(s) were characterized by comparison of their physical data with those of known compounds. Entry: 13 Product: 4m; Yield: 90% Mp: 208-210°C; Lit. Mp: 205-206 [23]°C

ETHYL 6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE synthesis

Synthesis of ETHYL 6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE from Ethyl acetoacetate and Benzaldehyde and Carbamimidothioic acid

ETHYL 6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE Preparation Products And Raw materials

Raw materials

Ethyl acetoacetate Benzaldehyde Carbamimidothioic acid

Preparation Products

ETHYL 6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE Suppliers

Global( 39)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9348	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418671	sales@tnjchem.com	China	34572	58
changzhou huayang technology co., ltd	+8615250961469	2571773637@qq.com	China	9821	58
GIHI CHEMICALS CO.,LIMITED	+8618058761490	info@gihichemicals.com	China	49999	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58
Chemwill Asia Co.,Ltd.	86-21-51086038	chemwill_asia@126.com	CHINA	23931	58
Shanghai Sphchem Co., Ltd.	21-21-56491756 13512199871	sales@panhongchem.com	China	3985	55

Supplier	Advantage
Hangzhou FandaChem Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Chongqing Chemdad Co., Ltd	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
changzhou huayang technology co., ltd	58
GIHI CHEMICALS CO.,LIMITED	58
Amadis Chemical Company Limited	58
Chemwill Asia Co.,Ltd.	58
Shanghai Sphchem Co., Ltd.	55

View Lastest Price from ETHYL 6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-07-06	ETHYL 6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE 33458-26-3	US $7.00 / KG	25KG	99%	100TONS	Career Henan Chemical Co

ETHYL 6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE
33458-26-3
US $7.00 / KG
99%
Career Henan Chemical Co

33458-26-3(ETHYL 6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE)Related Search:

ETHYL 6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE ETHYL 4-(4-ETHOXYPHENYL)-6-METHYL-2-THIOXO-1,2,3,4-TETRAHYDRO-5-PYRIMIDINECARBOXYLATE MONASTROL ETHYL 4-(4-METHOXYPHENYL)-6-METHYL-2-THIOXO-1,2,3,4-TETRAHYDRO-5-PYRIMIDINECARBOXYLATE 6-METHYL-2-THIOXO-4-P-TOLYL-1,2,3,4-TETRAHYDRO-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER

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4-(3-FLUORO-PHENYL)-6-METHYL-2-THIOXO-1,2,3,4-TETRAHYDRO-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER AURORA 1144 4-(2-CHLORO-PHENYL)-6-METHYL-2-THIOXO-1,2,3,4-TETRAHYDRO-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER

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5118-36-5 6-ME-4-PH-2-THIOXO-1,2,3,4-TETRAHYDRO-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER 4-methyl-6-phenyl-2-thioxo-3,6-dihydro-1H-pyrimidine-5-carboxylic acid ethyl ester A0951/0044480 ethyl 4-methyl-6-phenyl-2-sulfanylidene-3,6-dihydro-1H-pyrimidine-5-carboxylate ethyl 4-methyl-6-phenyl-2-thioxo-3,6-dihydro-1H-pyrimidine-5-carboxylate EU-006731 Maybridge1_006365 NCI60_014903 NSC643910 Oprea1_330764 Pyrimidine-5-carboxilyc acid, 1,2,3,4-tetrahydro-6-methyl-4-phenyl-2-thioxo-, ethyl ester SBB016167 5-Pyrimidinecarboxylicacid, 1,2,3,4-tetrahydro-6-methyl-4-phenyl-2-thioxo-, ethyl ester ETHYL 6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDRO-5-PYRIMIDINECARBOXYLATE ETHYL 6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE AURORA KA-3499 BUTTPARK 61\40-96 Pyrimidine-5-carboxilyc acid, 1,2,3,4-tetrahydro-6-methyl-4-phenyl-2-t hione-, ethyl ester 6-Methyl-4-phenyl-2-thioxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate 6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDRO-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER 5-pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-6-methyl-4 Ethyl 6-methyl-4-phenyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylate Ethyl 6-methyl-4-phenyl-2-sulfanylidene-1,2,3,4-tetrahydropyrimidine-5-carboxylate ethyl 6-methyl-4-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidin... 33458-26-3