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INDEX NAME NOT YET ASSIGNED
- CAS No.
- 2412056-48-3
- Chemical Name:
- INDEX NAME NOT YET ASSIGNED
- Synonyms
- Thalidomide-NH-PEG4-COOH;1-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)amino)-3,6,9,12-tetraoxapentadecan-15-oic acid
- CBNumber:
- CB08346359
- Molecular Formula:
- C24H31N3O10
- Molecular Weight:
- 521.52
- MDL Number:
- MOL File:
- 2412056-48-3.mol
Last updated:2023-04-23 13:52:06
INDEX NAME NOT YET ASSIGNED Chemical Properties,Uses,Production
Biological Activity
Thalidomide-NH-PEG4-COOH is an E3 ligase ligand-linker conjugate which can be used for synthesizing dCBP-1. dCBP-1 is a potent and selective heterobifunctional degrader of p300/CBP[1]. Thalidomide-NH-PEG4-COOH (S13) is the E3 ligase ligand-linker conjugate of dCBP-1[1].
References
[1]. Raghu Vannam, et al. Targeted degradation of the enhancer lysine acetyltransferases CBP and p300. Cell Chem Biol. 2020 Dec 31;S2451-9456(20)30513-4.
INDEX NAME NOT YET ASSIGNED Preparation Products And Raw materials
Raw materials
Preparation Products
INDEX NAME NOT YET ASSIGNED Suppliers
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Thalidomide-NH-PEG4-COOH
1-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)amino)-3,6,9,12-tetraoxapentadecan-15-oic acid
2412056-48-3
C24H31N3O10