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Letosteine

CAS No.
53943-88-7
Chemical Name:
Letosteine
Synonyms
Visoctiol;Viscotiol;Letosteine;2-(2-((2-ethoxy-2-oxoethyl)thio)ethyl)thiazolidine-4-carboxylic acid;2-[2-[(2-Ethoxy-2-oxoethyl)thio]ethyl]-4-thiazolidinecarboxylic acid;4-Thiazolidinecarboxylic acid, 2-[2-[(2-ethoxy-2-oxoethyl)thio]ethyl]-;2-[2-(2-Ethoxy-2-oxoethyl)sulfanylethyl]-1,3-thiazolidine-4-carboxylic acid
CBNumber:
CB0875396
Molecular Formula:
C10H17NO4S2
Molecular Weight:
279.38
MDL Number:
MOL File:
53943-88-7.mol
Last updated:2023-09-04 15:51:00

Letosteine Properties

Melting point 142°
Boiling point 470.0±45.0 °C(Predicted)
Density 1.284±0.06 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Dichloromethane (Slightly), DMSO (Slightly)
form Solid
pka 2.05±0.40(Predicted)
color White to Pale Yellow
CAS DataBase Reference 53943-88-7
FDA UNII 6MVF9U95DW
ATC code R05CB09

Letosteine price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC L330103 Letosteine 53943-88-7 100mg $50 2021-12-16 Buy
TRC L330103 Letosteine 53943-88-7 1g $220 2021-12-16 Buy
American Custom Chemicals Corporation API0010497 2-[2-(2-ETHOXY-2-OXOETHYL)SULFANYLETHYL]-1,3-THIAZOLIDINE-4-CARBOXYLIC ACID 95.00% 53943-88-7 1G $240.45 2021-12-16 Buy
AK Scientific J11158 Letosteine 53943-88-7 100mg $298 2021-12-16 Buy
AK Scientific J11158 Letosteine 53943-88-7 5mg $49 2021-12-16 Buy
Product number Packaging Price Buy
L330103 100mg $50 Buy
L330103 1g $220 Buy
API0010497 1G $240.45 Buy
J11158 100mg $298 Buy
J11158 5mg $49 Buy

Letosteine Chemical Properties,Uses,Production

Originator

Viscotiol,Carlo Erba,France,1979

Definition

ChEBI: A dicarboxylic acid monoester that is the monoethyl ester of 2-{2-[(carboxymethyl)sulfanyl]ethyl}-1,3-thiazolidine-4-carboxylic acid. A mucolytic used in the treatment of chronic bronchopneumopathies and related conditions.

Manufacturing Process

In an Erlenmeyer flask placed in an ice bath, and under a well-ventilated hood, a solution of 0.1 mol of acrolein in 100 ml of ether was introduced, With the aid of a bromine ampoule, 0.1 mol (= 11 ml) of the ethyl ester of thioglycolic acid containing 0.5 ml of triethylamine was added drop by drop.
One hour after completion of the addition, there was added 0.1 mol (15.6 g) of chlorhydrate of cysteine in alcoholic solution. The chlorhydrate of the expected derivative, which appeared in the form of a thick oil, was precipitated by addition of 0.1 mol (10 g) of potassium acetate in aqueous solution. The abundant precipitate obtained was filtered and washed in water and ether. The product was recrystallized in a minimum of absolute alcohol.

Therapeutic Function

Mucolytic

Letosteine Preparation Products And Raw materials

Raw materials

Preparation Products

Letosteine Suppliers

Global( 41)Suppliers
Supplier Tel Email Country ProdList Advantage
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293 sales@sdzschem.com China 2931 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 47465 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671 sales@tnjchem.com China 34572 58
Shandong Zhishang New Material Co., Ltd.
+8617653113209 sales002@sdzschem.com China 3050 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49739 58
GIHI CHEMICALS CO.,LIMITED
+8618058761490 info@gihichemicals.com China 49999 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 52927 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131981 58
TAIYUAN RHF CO.,LTD. +86 351 7031519 sales@RHFChem.com China 2341 56

View Lastest Price from Letosteine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
	Letosteine pictures 2020-01-09 Letosteine
53943-88-7
US $2.00 / KG 1KG 98% 1kg, 5kg ,50kg Career Henan Chemical Co
  • 	Letosteine pictures
  • Letosteine
    53943-88-7
  • US $2.00 / KG
  • 98%
  • Career Henan Chemical Co

Letosteine Spectrum

2-[2-(2-Ethoxy-2-oxoethyl)sulfanylethyl]-1,3-thiazolidine-4-carboxylic acid 4-Thiazolidinecarboxylic acid, 2-[2-[(2-ethoxy-2-oxoethyl)thio]ethyl]- Viscotiol Visoctiol 2-[2-[(2-Ethoxy-2-oxoethyl)thio]ethyl]-4-thiazolidinecarboxylic acid Letosteine 2-(2-((2-ethoxy-2-oxoethyl)thio)ethyl)thiazolidine-4-carboxylic acid 53943-88-7 C10H17NO4S2 API