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Tofacitinib

Tofacitinib
Tofacitinib structure
CAS No.
477600-75-2
Chemical Name:
Tofacitinib
Synonyms
CP 690550;Tofacitinib;Tasocitinib;477600-75-2;Tofaimpurity;Tofacitinib base;Tropsch iMatinib;Tofacitinib, >=98%;CP-690550 Tofacitinib;Tofacitinib,CP-690550
CBNumber:
CB0970901
Molecular Formula:
C16H20N6O
Formula Weight:
312.3696
MOL File:
477600-75-2.mol

Tofacitinib Properties

Density 
1.3
CAS DataBase Reference
477600-75-2

SAFETY

HS Code  29335990

Tofacitinib price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy

Tofacitinib Chemical Properties,Uses,Production

Chemical Properties

Light Pink to Pale Orange Solid

Uses

CP-690550 is a pyrrolo[2,3-d]pyrimidine derivative, as Janus kinase inhibitor for treatment of rheumatoid arthritis

Definition

ChEBI: A pyrrolopyrimidine that is pyrrolo[2,3-d]pyrimidine substituted at position 4 by an N-methyl,N-(1-cyanoacetyl-4-methylpiperidin-3-yl)amino moiety. Used as its citrate salt to treat moderately to severely ctive rheumatoid arthritis.

Indications

The JAK family includes four isoforms, JAK1, JAK2, JAK3, and tyrosine kinase (TYK2). Ruxolitinib (Jakafi(R), Incyte Corp.) was the first approved JAK inhibitor, which inhibits both JAK1 and JAK2, used for the treatment of different types of myelofibrosis. Tofacitinib (Xeljanz(R), Pfizer) was approved by FDA as a JAK3-selective inhibitor for the treatment of rheumatoid arthritis and is one of the only two FDA-approved kinase inhibitors for non-oncological indications.

Tofacitinib Preparation Products And Raw materials

Raw materials

Preparation Products


Tofacitinib Suppliers

Global( 247)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 sales@capotchem.com China 19954 60
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 22043 58
Beijing Cooperate Pharmaceutical Co.,Ltd.
+86-10-60279497 +86(0)15646567669
+86-10-60279497 sales01@cooperate-pharm.com CHINA 1530 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20786 55
Hubei XinRunde Chemical Co., Ltd.
+8615102730682; +8618874586545
02783214688 bruce@xrdchem.cn CHINA 552 55
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 16534 60
TianYuan Pharmaceutical CO.,LTD
+86-755-23284190 13684996853
+86-755-23284190 sales@tianpharm.com CHINA 308 58
Biochempartner
0086-13720134139
candy@biochempartner.com CHINA 956 58
Changzhou Ansciep Chemical Co., Ltd.
+86 519 86305871
+86 519 86305879 sales@ansciepchem.com CHINA 3112 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 24118 58

View Lastest Price from Tofacitinib manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-07-30 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
477600-75-2
US $100.00 / KG 1KG 98% 100KG career henan chemical co
2018-03-08 Tofacitinib
477600-75-2
US $100.00 / KG 10G 99% >99% Hubei XinRunde Chemical Co., Ltd.

477600-75-2(Tofacitinib)Related Search:


  • 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
  • CP 690550
  • 3-Piperidinamine, 1-(cyanoacetyl)-4-methyl-N-methyl-N-1H-pyrrolo(2,3-D)pyrimidin-4-yl-, (3R,4R)-
  • CP-690550(Tasocitinib,CP690550)
  • CP 690550(Tasocitinib)
  • Tasocitinib
  • 3-((3R,4R)-4-Methyl-3-(Me...
  • Tasocitinib (CP 690550)
  • 1-Piperidinepropanenitrile, 4-Methyl-3-(Methyl-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMino)-β-oxo-, (3R,4R)-
  • 1-Piperidinepropanenitrile, 4-Methyl-3-(Methyl-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMino)-beta-oxo-, (3R,4R)-
  • Tofacitinib
  • CP-690550 Tofacitinib
  • 3-((3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropa
  • Tofaimpurity
  • Tofacitinib base
  • Tofacitinib (CP-690550,Tasocitinib)
  • 3-((3R,4R)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)-2-oxopiperidin-1-yl)propanenitrile
  • Tropsch iMatinib
  • CP 690550 3-((3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
  • (3R,4R)-4-methyl-3-(methyl-1H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-β-oxo-2-piperidinepropanenitrile
  • (3R,4R)-4-methyl-3-(methyl-1H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-β-oxo-1-piperidinepropanenitrile
  • -
  • 477600-75-2
  • Inhibitor
  • Inhibitors
  • Tofacitinib,CP-690550
  • 477600-75-2
  • Tofacitinib, >=98%
  • 3-[4(R)-Methyl-3(R)-[N-methyl-N-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]- 3-oxopropanenitrile
  • 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile(CP-690550)
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