ChemicalBook >> CAS DataBase List >>Indisulam
Indisulam
- CAS No.
- 165668-41-7
- Chemical Name:
- Indisulam
- Synonyms
- D04522;E-7070;ER-35744;INDISULAM;IndisulaM (E7070);INDISULAM iMpurity;E7070;ER-35744;D04522;Indisulam >=98% (HPLC);IndisulaM (E7070) (ER-35744);N-(3-Chloro-1H-indol-7-yl)-1,4-benzenedisulfonamide
- CBNumber:
- CB11011305
- Molecular Formula:
- C14H12ClN3O4S2
- Molecular Weight:
- 385.85
- MDL Number:
- MFCD00945325
- MOL File:
- 165668-41-7.mol
Last updated:2023-09-04 16:42:00
| Melting point | 242-243 °C (decomp)(Solv: ethanol (64-17-5); water (7732-18-5)) |
|---|---|
| Boiling point | 668.9±65.0 °C(Predicted) |
| Density | 1.663±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMSO : 100 mg/mL (259.17 mM; Need ultrasonic) |
| form | powder |
| pka | 8.14±0.30(Predicted) |
| color | white to beige |
| NCI Dictionary of Cancer Terms | E7070 |
| FDA UNII | WJ98J3NM90 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313 | |||||||||
| NFPA 704 |
|
Indisulam price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1225 | Indisulam ≥98% (HPLC) | 165668-41-7 | 5MG | $142 | 2023-06-20 | Buy |
| Sigma-Aldrich | SML1225 | Indisulam ≥98% (HPLC) | 165668-41-7 | 25MG | $564 | 2023-06-20 | Buy |
| Cayman Chemical | 22759 | Indisulam ≥98% | 165668-41-7 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 22759 | Indisulam ≥98% | 165668-41-7 | 5mg | $116 | 2024-03-01 | Buy |
| Cayman Chemical | 22759 | Indisulam ≥98% | 165668-41-7 | 10mg | $214 | 2024-03-01 | Buy |
Indisulam Chemical Properties,Uses,Production
Definition
ChEBI: Indisulam is a chloroindole that is 3-chloro-1H-indole substituted by a [(4-sulfamoylphenyl)sulfonyl]nitrilo group at position 7. It is a carbonic anhydrase inhibitor and a potential anti-cancer agent currently in clinical development. It has a role as an EC 4.2.1.1 (carbonic anhydrase) inhibitor and an antineoplastic agent. It is a chloroindole, a sulfonamide and an organochlorine compound.
Biochem/physiol Actions
Indisulam is a carbonic anhydrase inibitor and Antitumor CDK inhibitor. Indisulam targets the G1 phase of the cell cycle by depleting cyclin E. inducing p53 and p21, and inhibiting CDK2, causing a blockade in the G1/S transition.
storage
Store at -20°C
Indisulam Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 89)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| Changzhou PBpharmaceutical R&D Co.,Ltd | 0519-83990708 | info@pbpharm.com | CHINA | 498 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19994 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
View Lastest Price from Indisulam manufacturers
INDISULAM
1,4-Benzenedisulfonamide, N-(3-chloro-1H-indol-7-yl)-
N-(3-Chloro-1H-indol-7-yl)-1,4-benzenedisulfonamide
E-7070
ER-35744
IndisulaM (E7070)
IndisulaM (E7070) (ER-35744)
N1-(3-Chloro-1H-indol-7-yl)benzene-1,4-disulfonamide
D04522
E7070;ER-35744;D04522
1,4-Benzenedisulfonamide, N1-(3-chloro-1H-indol-7-yl)-
Indisulam >=98% (HPLC)
N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonamide
E-7070,Indisulam,Carbonic Anhydrase,Inhibitor,Carbonate dehydratase,E7070,inhibit
INDISULAM iMpurity
165668-41-7
C14H12ClN3O4S2