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6-Bromo-1,2,3,4-tetrahydronaphthalen-2-amine

6-Bromo-1,2,3,4-tetrahydronaphthalen-2-amine structure

CAS No.: 167355-41-1

Chemical Name:: 6-Bromo-1,2,3,4-tetrahydronaphthalen-2-amine

Synonyms: 101397;6-bromo-1,2,3,4-tetrahydro-2-Naphthalenamine;6-Bromo-1,2,3,4-tetrahydronaphthalen-2-amine;2-Amino-6-bromo-1,2,3,4-tetrahydronaphthalene;6-Bromo-1,2,3,4-tetrahydro-phthalen-2-ylamine;2-Naphthalenamine, 6-bromo-1,2,3,4-tetrahydro-;6-BROMO-1,2,3,4-TETRAHYDRO-NAPHTHALEN-2-YLAMINE;6-BROMO-1,2,3,4-TETRAHYDRO-NAPHTHALEN-2-YLAMINE HYDROCHLORIDE

CBNumber:: CB1103355

Molecular Formula:: C10H12BrN

Molecular Weight:: 226.11

MDL Number:: MFCD06739165

MOL File:: 167355-41-1.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:44

Request For Quotation

6-Bromo-1,2,3,4-tetrahydronaphthalen-2-amine Properties

Boiling point	298.7±40.0 °C(Predicted)
Density	1.413±0.06 g/cm3(Predicted)
storage temp.	2-8°C(protect from light)
pka	10.02±0.20(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H319-H335-H302+H312+H332-H315
Precautionary statements	P305+P351+P338-P280-P301+P312
HS Code	2921490090

6-Bromo-1,2,3,4-tetrahydronaphthalen-2-amine price More Price(16)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
AK Scientific	8535AA	6-Bromo-1,2,3,4-tetrahydronaphthalen-2-amine	167355-41-1	100mg	$350	2021-12-16	Buy
American Custom Chemicals Corporation	HCH0049803	2-AMINO-6-BROMO-1,2,3,4-TETRAHYDRONAPHTHALENE 95.00%	167355-41-1	1G	$1331.6	2021-12-16	Buy
American Custom Chemicals Corporation	HCH0049803	2-AMINO-6-BROMO-1,2,3,4-TETRAHYDRONAPHTHALENE 95.00%	167355-41-1	5G	$3038.7	2021-12-16	Buy
Crysdot	CD12135092	6-Bromo-1,2,3,4-tetrahydronaphthalen-2-amine 97%	167355-41-1	5g	$1865	2021-12-16	Buy
Alichem	167355411	6-Bromo-1,2,3,4-tetrahydronaphthalen-2-amine	167355-41-1	5g	$2068	2021-12-16	Buy

Product number	Packaging	Price	Buy
8535AA	100mg	$350	Buy
HCH0049803	1G	$1331.6	Buy
HCH0049803	5G	$3038.7	Buy
CD12135092	5g	$1865	Buy
167355411	5g	$2068	Buy

6-Bromo-1,2,3,4-tetrahydronaphthalen-2-amine Chemical Properties,Uses,Production

Synthesis

4133-35-1

167355-41-1

General procedure: preparation of 6-bromo-1,2,3,4-tetrahydronaphthalen-2-amine. To a solution of methanol (100 mL) containing 6-bromo-3,4-dihydro-1H-2-naphthalenone (2 g, 8.89 mmol) and NH4OAc (5.52 g, 71.61 mmol), NaCNBH3 (0.67 g, 10.66 mmol) was added at room temperature. The reaction mixture was stirred at room temperature for 20 h. The solution was observed to turn yellow. After completion of the reaction, the reaction mixture was acidified with 2M HCl and stirred for 10 min, followed by evaporation to remove methanol. The mixture was extracted twice with dichloromethane (CH2Cl2). The aqueous layer was adjusted to pH 10 with 1.0 N NaOH and again extracted twice with dichloromethane (CH2Cl2). The organic layers were combined, dried over anhydrous MgSO4 and concentrated in vacuum to afford 1.31 g (65% yield) of the target product 6-bromo-1,2,3,4-tetrahydronaphthalen-2-amine as a yellow oil, which could be used in the subsequent reaction without further purification.LRMS: m/z 226.1 (M + H)+, 209 (M + H-NH3)+. Retention time: 3.84 min (Method B). 1H NMR (300 MHz, CD3OD) δ 7.27-7.35 (m, 8H), 7.05 (d, J = 8.4Hz, 4H), 3.56 (m, 1H), 3.17 (dd, J = 3.9,16.2Hz, 1H), 2.95 (m, 2H), 2.81 (dd, J = 9.9,16.2Hz, 1H), 2.19-2.29 (m, 1H), 1.79-1.92 (m, 1H).

References

[1] Patent: EP2202232, 2010, A1. Location in patent: Page/Page column 71
[2] Patent: WO2016/16162, 2016, A1. Location in patent: Page/Page column 21
[3] Patent: WO2016/33025, 2016, A1. Location in patent: Page/Page column 62-63
[4] Patent: WO2008/1160, 2008, A1. Location in patent: Page/Page column 21-23
[5] Patent: US2005/75324, 2005, A1. Location in patent: Page/Page column 9; 10

6-Bromo-1,2,3,4-tetrahydronaphthalen-2-amine Preparation Products And Raw materials

Raw materials

6-Bromo-2-tetralone Sodium cyanoborohydride Methanol Ammonium acetate

Preparation Products

6-Bromo-1,2,3,4-tetrahydronaphthalen-2-amine Suppliers

Global( 62)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+8613336195806	sales@capot.com	China	29731	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29804	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Shanghai UCHEM Inc.	+862156762820 +86-13564624040	sales@myuchem.com	China	8257	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52846	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58
GIHI CHEMICALS CO.,LIMITED	+8618058761490	info@gihichemicals.com	China	49983	58
Aladdin Scientific		tp@aladdinsci.com	United States	52924	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
Alchem Pharmtech,Inc.	58
career henan chemical co	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Shanghai UCHEM Inc.	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	58
GIHI CHEMICALS CO.,LIMITED	58
Aladdin Scientific	58

View Lastest Price from 6-Bromo-1,2,3,4-tetrahydronaphthalen-2-amine manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-01-03	6-Bromo-1,2,3,4-tetrahydronaphthalen-2-amine 167355-41-1	US $6.60 / KG	1KG	97%-99%	1kg -1000kg	Career Henan Chemical Co

6-Bromo-1,2,3,4-tetrahydronaphthalen-2-amine
167355-41-1
US $6.60 / KG
97%-99%
Career Henan Chemical Co

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2-Amino-6-bromo-1,2,3,4-tetrahydronaphthalene 6-BROMO-1,2,3,4-TETRAHYDRO-NAPHTHALEN-2-YLAMINE 6-BROMO-1,2,3,4-TETRAHYDRO-NAPHTHALEN-2-YLAMINE HYDROCHLORIDE 6-Bromo-1,2,3,4-tetrahydronaphthalen-2-amine 6-bromo-1,2,3,4-tetrahydro-2-Naphthalenamine 101397 6-Bromo-1,2,3,4-tetrahydro-phthalen-2-ylamine 2-Naphthalenamine, 6-bromo-1,2,3,4-tetrahydro- 167355-41-1 167-35-5