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Pralmorelin

CAS No.
158861-67-7
Chemical Name:
Pralmorelin
Synonyms
GHRP-2;GHRP;CHRP-2;GHRP-2 ACETATE;GHCA;EIF3A;d-ala-β-(2-naphthyl)-d-ala-trp-d-phe-lys amide;-2;-2;p-ERK1
CBNumber:
CB1104514
Molecular Formula:
C45H55N9O6
Molecular Weight:
817.97
MDL Number:
MFCD00674876
MOL File:
158861-67-7.mol
Last updated:2024-04-25 17:59:01

Pralmorelin Properties

Melting point 149 - 151°C
Boiling point 1265.3±65.0 °C(Predicted)
Density 1.270±0.06 g/cm3(Predicted)
storage temp. −20°C
solubility DMSO (Slightly, Sonicated), Water (Slightly)
pka 13.40±0.46(Predicted)
form lyophilized powder
color white to beige
Stability Hygroscopic
InChIKey HRNLPPBUBKMZMT-RDRUQFPZSA-N
SMILES C(N)(=O)[C@H](CCCCN)NC(=O)[C@@H](CC1=CC=CC=C1)NC(=O)[C@H](CC1C2=C(C=CC=C2)NC=1)NC(=O)[C@H](C)NC(=O)[C@@H](CC1=CC=C2C(=C1)C=CC=C2)NC(=O)[C@@H](C)N
CAS DataBase Reference 158861-67-7(CAS DataBase Reference)
FDA UNII E6S6E1F19M

SAFETY

Risk and Safety Statements

WGK Germany  3

Pralmorelin price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML2056 Pralmorelin trifluoroacetate salt ≥97% (HPLC) 158861-67-7 1MG $162 2023-01-07 Buy
Sigma-Aldrich SML2056 Pralmorelin trifluoroacetate salt ≥97% (HPLC) 158861-67-7 5MG $650 2023-01-07 Buy
Alfa Aesar J66029 Growth Hormone Releasing Peptide-2 158861-67-7 25mg $270 2021-12-16 Buy
Alfa Aesar J66029 Growth Hormone Releasing Peptide-2 158861-67-7 5mg $113 2021-12-16 Buy
Usbiological 382743 eIF3A 158861-67-7 96Tests $729 2021-12-16 Buy
Product number Packaging Price Buy
SML2056 1MG $162 Buy
SML2056 5MG $650 Buy
J66029 25mg $270 Buy
J66029 5mg $113 Buy
382743 96Tests $729 Buy

Pralmorelin Chemical Properties,Uses,Production

Description

Pralmorelin (also known as KP-102, GPA-748, GHRP-2, and Growth Hormone Releasing Peptide-2)  is a potent GH secretagogue in development as a diagnostic agent for growth hormone deficiency and for the treatment of pituitary disorders and GH deficiency. It acts as signal molecules that are involved in the control of cell growth and differentiation.

Uses

Growth hormone releasing factor. Pralmorelin is a growth hormone secretagogue that acts on the pituitary gland and the hypothalamus to stimulate and amplify pulsatile growth hormone release.

Definition

ChEBI: Pralmorelin is an oligopeptide.

benefits

Regulation of blood pressure, increased strength and healing, reduced injury, increased cell rejuvenation, increase in lean muscle mass and stronger bones.

Biochem/physiol Actions

Pralmorelin, also known as Growth hormone-releasing peptide 2 or GHRP-2, is an orally-active, synthetic peptide analogue of met-enkephalin that acts as a ghrelin/growth hormone secretagogue receptor (GHSR) agonist to selectively stimulate the ghrelin receptor and cause growth hormone release. Pralmorelin (GHRP-2) has been used clinically for the assessment of growth hormone deficiency (GHD), It has also been shown to have anti-inflammatory activity.

Mechanism of action

GHRP-2 is an agonist of ghrelin, a gut peptide and also known as “the hunger hormone”, which binds to the growth hormone secretagogue receptor. Pralmorelin works to enhance natural growth hormone production in two ways. First, the GHRP-2 intensifies the natural growth hormone releasing signal, resulting in a substantial secretion of growth hormone. Second, it suppresses a hormone in the body called somatostatin, also known as growth hormone inhibiting hormone (GHIH). Somatostatin generates the body to decrease its natural growth hormone production. By restricting the activity of somatostatin, GHRP-2 can improve growth hormone creation, resulting in increased natural growth hormone levels. GHRP-2 also activates ghrelin, a peptide hormone produced in the gastrointestinal system, which has strong effects on growth hormone production and appetite.

Pralmorelin Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 267)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Dangtong Import and export Co LTD
+8615632927689 admin@hbdangtong.com China 991 58
Zhuzhou New Peptides Tech Co.,Ltd.
+8618073326374 sales@goodpeptides.com China 140 58
Sichuan Tai Hui Biotechnology Co., Ltd
+86-18224031330 +86-18081096520 404435307@qq.com China 23 58
Nantong Guangyuan Chemicl Co,Ltd
+undefined17712220823 admin@guyunchem.com China 616 58
Henan Tengmao Chemical Technology Co. LTD
+8615238638457 salesvip2@hntmhg.com China 415 58
hebei hongtan Biotechnology Co., Ltd
+86-86-1913198-3935 +8617331935328 sales03@chemcn.cn China 951 58
CONTIDE BIOTECH CO.,LTD
+85253358525 xena@healthtide-api.com China 499 58
Hebei Mojin Biotechnology Co., Ltd
+8613288715578 sales@hbmojin.com China 12456 58
Hebei Yime New Material Technology Co., Ltd.
+86-66697723 +86-17703311139 admin@china-yime.com China 563 58
Shanghai Yunao International Trade Co., Ltd
+8617621705551 asdf@shanghaihg.cn China 265 58

View Lastest Price from Pralmorelin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ghrp 2  pictures 2024-04-25 Ghrp 2
158861-67-7
US $30.00 / kit 1kit 99% 100000 kits Guangdong Tuoyuan Biotechnology Co., LTD
GHRP-2 Acetate pictures 2024-04-25 GHRP-2 Acetate
158861-67-7
US $80.00-50.00 / box 2box 99% 100000kg Hebei Kangcang new material Technology Co., LTD
GHRP-2 Acetate pictures 2024-04-25 GHRP-2 Acetate
158861-67-7
US $0.00 / G 1G 99% 20kg CONTIDE BIOTECH CO.,LTD
  • Ghrp 2  pictures
  • Ghrp 2
    158861-67-7
  • US $30.00 / kit
  • 99%
  • Guangdong Tuoyuan Biotechnology Co., LTD
  • GHRP-2 Acetate pictures
  • GHRP-2 Acetate
    158861-67-7
  • US $80.00-50.00 / box
  • 99%
  • Hebei Kangcang new material Technology Co., LTD

Pralmorelin Spectrum

D-ALANYL-3-(2-NAPHTHALENYL)-D-ALANYL-L-ALANYL-L-TRYPTOPHYL-D-PHENYLALANYL-L-LYSINAMIDE ACETATE ADDUCT GHRP-2 (FREE PEPTIDE) (2S)-6-amino-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-amino-3-naphthalen-2-yl-propanoyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenyl-propanoyl]amino]-N-[(2R)-2-aminopropanoyl]hexanamide D-Ala-bata-(2-naphthyl)-D-Ala-Trp-D-Phe-Lys amide D-Alanyl-3-(2-naphthalenyl)-D-alanyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide D-Ala-D-β-Nal-Ala-Trp-D-Phe-Lys-NH2 4-dichloro-1 8-naphthyridine 3-d]pyriMidine TFA 2-trifluoroethyl)thiazole 5-(Tributylstannyl)-2-(2 3-a]pyrazine-3 4]triazolo[4 6-dihydro-[1 7-tert-butyl 3-ethyl 5 7-naphthyridine-3 7-tert-butyl 3-Methyl 5 4]triazine-6-carboxylate ethyl 4-chloropyrrolo[1 tert-butyl 3-Methoxy-5 2-trifluoroethyl)cyclopropyl)stannane Tributyl(2-(2 Growth HorMone Releasing Hexapeptide-2 Monoclonal Anti-MAP Kinase, Activated (Diphosphorylated ERK-1& GH secretagogue receptor GH-releasing peptide receptor GHS receptor Acetic acid ghrelin -2 L-Lysinamide, D-alanyl-3-(2-naphthalenyl)-D-alanyl-L-alanyl-L-tryptophyl-D-phenylalanyl- PRALMORELIN D-ALA-D-NAL(2)-ALA-TRP-D-PHE-LYS-NH2 ACETATE SALT D-ALA-BETA-(2-NAPHTHYL)-D-ALA-TRP-D-PHE-LYS AMIDE D-ALA-D-2-NAL-ALA-TRP-D-PHE-LYS-NH2 (DES-ALA3,D-ALA1,D-2-NAL2)-GHRP-6 (DES-ALA3)-GHRP-2 (DES-ALA3)-GROWTH HORMONE-RELEASING PEPTIDE-2 (DES-ALA3)-KP-102 (DES-ALA3)-PRALMORELIN (DES-ALA8,D-ALA6,D-2-NAL7,D-PHE10)-ALPHA-MSH (6-11) AMIDE H-D-ALA-D-2-NAL-ALA-TRP-D-PHE-LYS-NH2 H-D-ALA-D-2-NAL-TRP-D-PHE-LYS-NH2 H-D-ALA-D-ALA(2-NAPHTHYL)-TRP-D-PHE-LYS-NH2 GROWTH HORMONE RELEASING PROTEIN-2 (D-ALA1,D-2-NAL2)-GHRP-6 TRIFLUOROACETATE SALT D-ala-B-(2-naphthyl)-D-ala-trp-D-phe-*lys amide -2 (Tetrahydro-2H-pyran-4-yl)methoxy=pyrimidine-4-carboxylic acid Bovine Viral Diarrhea Virus Type 1,2, gp53 (BVDV-1& 2 (Gamma-aminobutyric acid Receptor Subunit gamma-2, GABA(A) Receptor Subunit gamma-2, GABRG2, GABAAR&gamma Macroglobulin &alpha Chikungunya (CHIKV-Env 1 & Laminin &alpha DNA pol &gamma PLC &beta 1, phosphorylated (Y405) GCS-&beta Laminin &gamma IL-13R&alpha