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2-Amino-4-(trifluoromethyl)benzoic acid

2-Amino-4-(trifluoromethyl)benzoic acid Structure
2-Amino-4-(trifluoromethyl)benzoic acid structure
CAS No.
402-13-1
Chemical Name:
2-Amino-4-(trifluoromethyl)benzoic acid
Synonyms
2-aMino-4-(trifluoroMethoxy)benzoic acid;BUTTPARK 24\07-91;Terbinafine Impurity 40;2-Amino-4-Trifluoromethylbenzo;4-(trifluoromethyl)anthranilic acid;2-aMino-4-trifluoroMethylbenaoic acid;2-Amino-4-(trifluoromethyl)benzoic acid;Benzoic acid,2-aMino-4-(trifluoroMethyl)-;2-AMINO-4-TRIFLUOROMETHYLBENZOIC ACID 98%;2-Amino-4-(trifluoromethyl)benzoic Acid >
CBNumber:
CB1111066
Molecular Formula:
C8H6F3NO2
Molecular Weight:
205.13
MDL Number:
MFCD00519334
MOL File:
402-13-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:48:35
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2-Amino-4-(trifluoromethyl)benzoic acid Properties

Melting point 175-176°C
Boiling point 296.0±40.0 °C(Predicted)
Density 1.489±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
form powder to crystalline
pka 4.43±0.10(Predicted)
color White to Amber
Sensitive Air Sensitive
InChI InChI=1S/C8H6F3NO2/c9-8(10,11)4-1-2-5(7(13)14)6(12)3-4/h1-3H,12H2,(H,13,14)
InChIKey NQTLZJODEOHALT-UHFFFAOYSA-N
SMILES C(O)(=O)C1=CC=C(C(F)(F)F)C=C1N
CAS DataBase Reference 402-13-1(CAS DataBase Reference)
UNSPSC Code 12352106

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
target organs Respiratory system
Hazard Codes  Xi
Risk Statements  36-36/37/38
Safety Statements  26-36/37/39
WGK Germany  WGK 3
HazardClass  IRRITANT
HS Code  29215900
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
0
2 0

2-Amino-4-(trifluoromethyl)benzoic acid price More Price(53)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich CDS003877 2-Amino-4-(trifluoromethyl)benzoic acid AldrichCPR 402-13-1 250 mg $77.9 2026-04-30 Buy
TCI Chemical A2175 2-Amino-4-(trifluoromethyl)benzoic Acid >97.0%(HPLC)(T) 402-13-1 5g $67 2026-04-30 Buy
TCI Chemical A2175 2-Amino-4-(trifluoromethyl)benzoic Acid >97.0%(HPLC)(T) 402-13-1 25g $267 2026-04-30 Buy
Biosynth FA64180 2-Amino-4-(trifluoromethyl)benzoic acid 402-13-1 50g $150 2026-06-04 Buy
Apolloscientific PC9193 2-Amino-4-(trifluoromethyl)benzoic acid 98% 402-13-1 5g $21 2026-06-04 Buy
Product number Packaging Price Buy
CDS003877 250 mg $77.9 Buy
A2175 5g $67 Buy
A2175 25g $267 Buy
FA64180 50g $150 Buy
PC9193 5g $21 Buy

2-Amino-4-(trifluoromethyl)benzoic acid Chemical Properties, Uses, Production

Chemical Properties

Light yellow solid

Synthesis

2-Nitro-4-trifluoromethylbenzoic acid

320-94-5

2-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID

402-13-1

b) Synthesis of 2-amino-4-trifluoromethylbenzoic acid: 250 g of 2-nitro-4-trifluoromethylbenzoic acid (1.06 mol) was dissolved in 1 liter of ethanol and 7.5 g of 5% palladium/carbon catalyst was added. The reaction mixture was subjected to hydrogenation under hydrogen pressure of 1-2.5 bar. During the reaction, the temperature was gradually increased from 10 °C to 104 °C. After 2 h, the hydrogenation reaction was completed. Subsequently, the catalyst was removed by filtration and the solvent was evaporated under reduced pressure to give 215 g (99% yield) of a light yellow solid product with a melting point of 174-176 °C.

References

[1] Patent: WO2006/108591, 2006, A1. Location in patent: Page/Page column 10; 66
[2] Patent: US2005/124681, 2005, A1. Location in patent: Page/Page column 16
[3] Patent: WO2009/96701, 2009, A2. Location in patent: Page/Page column 28
[4] Journal of Medicinal Chemistry, 1996, vol. 39, # 5, p. 1172 - 1188
[5] Patent: WO2006/125555, 2006, A2. Location in patent: Page/Page column 96

2-Amino-4-(trifluoromethyl)benzoic acid synthesis

320-94-5
402-13-1
Synthesis of 2-Amino-4-(trifluoromethyl)benzoic acid from 2-Nitro-4-trifluoromethylbenzoic acid

2-Amino-4-(trifluoromethyl)benzoic acid Preparation Products And Raw materials

Raw materials

2-Hydroxyimino-N-(3-trifluoromethyl-phenyl)-acetamide 4-Amino-3-nitrobenzotrifluoride 6-Trifluoromethyl isatin 2-amino-4-(trifluoromethyl)benzamide 2-Nitro-4-trifluoromethylbenzoic acid
2-Nitro-4-(trifluoromethyl)benzonitrile 3-Aminobenzotrifluoride 4-(Trifluoromethyl)benzoic acid Ethanol Hydrogen

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Preparation Products

N-[5,8,13,14-tetrahydro-5,8,14-trioxo-11-(trifluoromethyl)naphth[2,3-c]acridin-6-yl]benzamide 2-Amino-4-(trifluoromethyl)benzenemethanol

2-Amino-4-(trifluoromethyl)benzoic acid Suppliers

Global Suppliers ( 202)
Supplier Tel Email Country ProdList Advantage
WUXI SHUANGQI TECHNOLOGY CO LTD. 18114865355 18055643310 1702606491@qq.com China 1104 58
Changzhou Yanji Biotechnology Co., Ltd. 0519-83556355 18015005120 shikewei397@163.com China 3732 55
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 18918157536; sales8178@energy-chemical.com China 45000 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. +86-21-54098501 sales@sinch.com.cn China 11592 64
Changzhou Huanling Chemical Co., Ltd. 89803005 18206112582 info@huanlingchem.com China 983 68
Shanghai Longsheng chemical Co.,Ltd. 58099637 13585536065 sales@shlschem.com China 9880 59
Supplier Advantage
WUXI SHUANGQI TECHNOLOGY CO LTD. 58
Changzhou Yanji Biotechnology Co., Ltd. 55
J & K SCIENTIFIC LTD. 76
TCI (Shanghai) Development Co., Ltd. 81
Energy Chemical 61
Wuhan Chemwish Technology Co., Ltd 56
Capot Chemical Co., Ltd 66
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. 64
Changzhou Huanling Chemical Co., Ltd. 68
Shanghai Longsheng chemical Co.,Ltd. 59

View Latest Price from 2-Amino-4-(trifluoromethyl)benzoic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Amino-4-(trifluoromethyl)benzoic acid pictures 2022-02-21 2-Amino-4-(trifluoromethyl)benzoic acid
402-13-1
 1KG 97.6% 100 tons Honest Joy Holdings Limited
2-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID pictures 2021-08-12 2-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID
402-13-1
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
2-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID pictures 2019-07-14 2-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID
402-13-1
 $1.00 1KG 99% 100kg Career Henan Chemical Co

2-Amino-4-(trifluoromethyl)benzoic acid Spectrum

2-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID(402-13-1)1HNMR2-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID(402-13-1)FT-IR

402-13-1 (2-Amino-4-(trifluoromethyl)benzoic acid) Related Search:

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Benzoic acid,2-aMino-4-(trifluoroMethyl)- BUTTPARK 24\07-91 4-(trifluoromethyl)anthranilic acid 2-Amino-4-Trifluoromethylbenzo 2-AMINO-4-TRIFLUOROMETHYLBENZOIC ACID 98% 2-aMino-4-trifluoroMethylbenaoic acid 4-(Trifluoromethyl)anthranilic acid, 4-Carboxy-alpha,alpha,alpha-trifluoro-m-toluidine 2-Amino-4-(trifluoromethyl)benzoic Acid > 2-Amino-4-(Trifluoromethyl)Benzoic Acid,>98% 2-Amino-4-(trifluoromethyl)benzoic Acid,4-(Trifluoromethyl)anthranilic Acid Terbinafine Impurity 40 2-aMino-4-(trifluoroMethoxy)benzoic acid 2-Amino-4-(trifluoromethyl)benzoic acid 402-13-1 Fluorine series Benzoic acid Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts