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2-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID

CAS No.
402-13-1
Chemical Name:
2-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID
Synonyms
2-aMino-4-(trifluoroMethoxy)benzoic acid;BUTTPARK 24\07-91;Terbinafine Impurity 40;2-Amino-4-Trifluoromethylbenzo;4-(trifluoromethyl)anthranilic acid;2-aMino-4-trifluoroMethylbenaoic acid;2-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID;Benzoic acid,2-aMino-4-(trifluoroMethyl)-;2-AMINO-4-TRIFLUOROMETHYLBENZOIC ACID 98%;2-Amino-4-(trifluoromethyl)benzoic Acid >
CBNumber:
CB1111066
Molecular Formula:
C8H6F3NO2
Molecular Weight:
205.13
MDL Number:
MFCD00519334
MOL File:
402-13-1.mol
Last updated:2025-07-24 18:13:48
Product description Number Pack Size Price
2-Amino-4-(trifluoromethyl)benzoic acid AldrichCPR CDS003877 250 mg $73.1
2-Amino-4-(trifluoromethyl)benzoic Acid >97.0%(HPLC)(T) A2175 5g $84
2-Amino-4-(trifluoromethyl)benzoic Acid >97.0%(HPLC)(T) A2175 25g $334
2-Amino-4-(trifluoromethyl)benzoic Acid A633485 500mg $60
2-Amino-4-(trifluoromethyl)benzoic Acid A633485 2.5g $75
More product size

2-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID Properties

Melting point 175-176°C
Boiling point 296.0±40.0 °C(Predicted)
Density 1.489±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
form powder to crystalline
pka 4.43±0.10(Predicted)
color White to Amber
Sensitive Air Sensitive
InChI InChI=1S/C8H6F3NO2/c9-8(10,11)4-1-2-5(7(13)14)6(12)3-4/h1-3H,12H2,(H,13,14)
InChIKey NQTLZJODEOHALT-UHFFFAOYSA-N
SMILES C(O)(=O)C1=CC=C(C(F)(F)F)C=C1N
CAS DataBase Reference 402-13-1(CAS DataBase Reference)
UNSPSC Code 12352106

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
Hazard Codes  Xi
Risk Statements  36-36/37/38
Safety Statements  26-36/37/39
HazardClass  IRRITANT
HS Code  29215900
NFPA 704
0
2 0

2-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID price More Price(31)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich CDS003877 2-Amino-4-(trifluoromethyl)benzoic acid AldrichCPR 402-13-1 250 mg $73.1 2025-07-31 Buy
TCI Chemical A2175 2-Amino-4-(trifluoromethyl)benzoic Acid >97.0%(HPLC)(T) 402-13-1 5g $84 2025-07-31 Buy
TCI Chemical A2175 2-Amino-4-(trifluoromethyl)benzoic Acid >97.0%(HPLC)(T) 402-13-1 25g $334 2025-07-31 Buy
TRC A633485 2-Amino-4-(trifluoromethyl)benzoic Acid 402-13-1 500mg $60 2021-12-16 Buy
TRC A633485 2-Amino-4-(trifluoromethyl)benzoic Acid 402-13-1 2.5g $75 2021-12-16 Buy
Product number Packaging Price Buy
CDS003877 250 mg $73.1 Buy
A2175 5g $84 Buy
A2175 25g $334 Buy
A633485 500mg $60 Buy
A633485 2.5g $75 Buy

2-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID Chemical Properties,Uses,Production

Chemical Properties

Light yellow solid

Synthesis

2-Nitro-4-trifluoromethylbenzoic acid

320-94-5

2-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID

402-13-1

b) Synthesis of 2-amino-4-trifluoromethylbenzoic acid: 250 g of 2-nitro-4-trifluoromethylbenzoic acid (1.06 mol) was dissolved in 1 liter of ethanol and 7.5 g of 5% palladium/carbon catalyst was added. The reaction mixture was subjected to hydrogenation under hydrogen pressure of 1-2.5 bar. During the reaction, the temperature was gradually increased from 10 °C to 104 °C. After 2 h, the hydrogenation reaction was completed. Subsequently, the catalyst was removed by filtration and the solvent was evaporated under reduced pressure to give 215 g (99% yield) of a light yellow solid product with a melting point of 174-176 °C.

References

[1] Patent: WO2006/108591, 2006, A1. Location in patent: Page/Page column 10; 66
[2] Patent: US2005/124681, 2005, A1. Location in patent: Page/Page column 16
[3] Patent: WO2009/96701, 2009, A2. Location in patent: Page/Page column 28
[4] Journal of Medicinal Chemistry, 1996, vol. 39, # 5, p. 1172 - 1188
[5] Patent: WO2006/125555, 2006, A2. Location in patent: Page/Page column 96

320-94-5
402-13-1
Synthesis of 2-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID from 2-Nitro-4-trifluoromethylbenzoic acid
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Capot Chemical Co.,Ltd.
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View Lastest Price from 2-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Amino-4-(trifluoromethyl)benzoic acid pictures 2022-02-21 2-Amino-4-(trifluoromethyl)benzoic acid
402-13-1
US $0.00 / KG 1KG 97.6% 100 tons Honest Joy Holdings Limited
2-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID pictures 2021-08-12 2-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID
402-13-1
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
2-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID pictures 2019-07-14 2-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID
402-13-1
US $1.00 / KG 1KG 99% 100kg Career Henan Chemical Co
Benzoic acid,2-aMino-4-(trifluoroMethyl)- 2-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID BUTTPARK 24\07-91 4-(trifluoromethyl)anthranilic acid 2-Amino-4-Trifluoromethylbenzo 2-AMINO-4-TRIFLUOROMETHYLBENZOIC ACID 98% 2-aMino-4-trifluoroMethylbenaoic acid 4-(Trifluoromethyl)anthranilic acid, 4-Carboxy-alpha,alpha,alpha-trifluoro-m-toluidine 2-Amino-4-(trifluoromethyl)benzoic Acid > 2-Amino-4-(Trifluoromethyl)Benzoic Acid,>98% 2-Amino-4-(trifluoromethyl)benzoic Acid,4-(Trifluoromethyl)anthranilic Acid 2-aMino-4-(trifluoroMethoxy)benzoic acid Terbinafine Impurity 40 402-13-1 Fluorine series Benzoic acid Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts