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(R)-(+)-2-BENZYLOXYPROPIONIC ACID

(R)-(+)-2-BENZYLOXYPROPIONIC ACID Structure
(R)-(+)-2-BENZYLOXYPROPIONIC ACID structure
CAS No.
100836-85-9
Chemical Name:
(R)-(+)-2-BENZYLOXYPROPIONIC ACID
Synonyms
O-BENZYL-D-LACTIC ACID;(R)-(+)-O-Benzyllactic acid;(R)-2-(Benzyloxy)propanoic acid;(2R)-2-(benzyloxy)propanoic acid;(2R)-2-(Benzyloxy)propionic acid;(R)-(+)-2-BENZYLOXYPROPIONIC ACID;(R)-2-(Benzyloxy)propanoic acid ee;(2R)-2-phenylmethoxypropanoic acid;Propanoic acid, 2-(phenylMethoxy)-, (2R)-;(R)-(+)-2-(Benzyloxy)propionic acid[>=97.0% (HPLC)]
CBNumber:
CB1111778
Molecular Formula:
C10H12O3
Molecular Weight:
180.2
MDL Number:
MFCD06799065
MOL File:
100836-85-9.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:45
Product description Number Pack Size Price
(R)-(+)-2-BenzyloxypropionicAcid B289173 50mg $60
(R)-(+)-2-BenzyloxypropionicAcid B289173 250mg $75
(R)-(+)-2-BenzyloxypropionicAcid B289173 25mg $45
(R)-(+)-2-Benzyloxypropionicacid ≥98.0% CS-M3394 5g $68
(R)-(+)-2-Benzyloxypropionicacid ≥98.0% CS-M3394 100g $604
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(R)-(+)-2-BENZYLOXYPROPIONIC ACID Properties

Melting point 52-55 °C
Boiling point 328.2±17.0 °C(Predicted)
Density 1.150
storage temp. Sealed in dry,Room Temperature
pka 3.57±0.10(Predicted)
Appearance Off-white to yellow <43°C Solid,>43°C Liquid
Water Solubility Insoluble in water.
BRN 4675524
InChI InChI=1S/C10H12O3/c1-8(10(11)12)13-7-9-5-3-2-4-6-9/h2-6,8H,7H2,1H3,(H,11,12)/t8-/m1/s1
InChIKey XWAVPOFYNPXXEL-MRVPVSSYSA-N
SMILES C(O)(=O)[C@H](OCC1=CC=CC=C1)C
CAS DataBase Reference 100836-85-9

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H317-H319-H335
Precautionary statements  P261-P280-P305+P351+P338-P280a-P304+P340-P405-P501a
Hazard Codes  Xi
Risk Statements  36/37/38-43
Safety Statements  26-36/37
WGK Germany  3
NFPA 704
0
2 0

(R)-(+)-2-BENZYLOXYPROPIONIC ACID price More Price(21)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC B289173 (R)-(+)-2-BenzyloxypropionicAcid 100836-85-9 50mg $60 2021-12-16 Buy
TRC B289173 (R)-(+)-2-BenzyloxypropionicAcid 100836-85-9 250mg $75 2021-12-16 Buy
TRC B289173 (R)-(+)-2-BenzyloxypropionicAcid 100836-85-9 25mg $45 2021-12-16 Buy
ChemScene CS-M3394 (R)-(+)-2-Benzyloxypropionicacid ≥98.0% 100836-85-9 5g $68 2021-12-16 Buy
ChemScene CS-M3394 (R)-(+)-2-Benzyloxypropionicacid ≥98.0% 100836-85-9 100g $604 2021-12-16 Buy
Product number Packaging Price Buy
B289173 50mg $60 Buy
B289173 250mg $75 Buy
B289173 25mg $45 Buy
CS-M3394 5g $68 Buy
CS-M3394 100g $604 Buy

(R)-(+)-2-BENZYLOXYPROPIONIC ACID Chemical Properties,Uses,Production

Uses

(R)-(+)-2-Benzyloxypropionic acid is used as a pharmaceutical intermediate.

Synthesis

Methyl (R)-2-(Benzyloxy)propionate

115458-99-6

(R)-(+)-2-BENZYLOXYPROPIONIC ACID

100836-85-9

The general procedure for the synthesis of (R)-2-(benzyloxy)propionic acid from methyl (R)-2-(benzyloxy)propionate was as follows: potassium hydroxide (KOH, 9.2 g, 163.96 mmol, 3.00 eq.) was added to methyl (2R)-2-(benzyloxy)propionate (11 g, 56.63 mmol, 1.00 eq.) in a methanol/water (90 mL/10 mL) solution. The reaction mixture was stirred at room temperature for 30 minutes. Upon completion of the reaction, the reaction mixture was concentrated and subsequently diluted with water. The resulting aqueous solution was washed with ethyl acetate and the pH of the aqueous layer was adjusted with aqueous hydrochloric acid to 5. The acidified aqueous layer was extracted with ethyl acetate, the organic layers were combined and washed with saturated brine. The organic layer was dried over anhydrous sodium sulfate and concentrated in vacuum to give 9.6 g (94% yield) of (2R)-2-(benzyloxy)propionic acid as a colorless oil.LC-MS detection showed [M + H]+ = 179.

References

[1] Patent: WO2015/138934, 2015, A1. Location in patent: Paragraph 00174
[2] Tetrahedron Letters, 1998, vol. 39, # 8, p. 779 - 782
[3] Chemistry - A European Journal, 2015, vol. 21, # 26, p. 9370 - 9379
[4] Angewandte Chemie - International Edition, 2015, vol. 54, # 16, p. 4919 - 4922
[5] Angew. Chem., 2015, vol. 127, # 16, p. 5001 - 5004,4

(R)-(+)-2-BENZYLOXYPROPIONIC ACID synthesis

29617-66-1
100-51-6
100836-85-9
Synthesis of (R)-(+)-2-BENZYLOXYPROPIONIC ACID from (S)-(-)-2-Chloropropionic acid and Benzyl alcohol

(R)-(+)-2-BENZYLOXYPROPIONIC ACID Preparation Products And Raw materials

Raw materials

Oxazolidine, 4-phenyl-2-(trifluoromethyl)-, (2S,4R)- (S)-(-)-2-Chloropropionic acid Methyl (R)-2-(Benzyloxy)propionate Benzyl alcohol Potassium hydroxide
Water Methanol

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Preparation Products

(R)-(+)-2-BENZYLOXYPROPIONIC ACID Suppliers

Global( 88)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 20124 58
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 10404 58
Accela ChemBio Inc. 		+1-858-6993322 info@accelachem.com United States 21193 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49977 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29795 58
Fuxin Pharmaceutical 		+86-021-021-50872116 +8613122107989 contact@fuxinpharm.com China 10000 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		+8613580539051 joe@yuhengpharm.com CHINA 21142 58
Finetech Industry Limited 		+86-27-8746-5837 +8619945049750 info@finetechnology-ind.com China 9541 58
Hangzhou Huarong Pharm Co., Ltd. 		571-86758373 +8613588754946 sales@huarongpharm.com CHINA 3148 58
sgtlifesciences pvt ltd 		+8617013299288 dj@sgtlifesciences.com China 12373 58
Supplier Advantage
Henan Fengda Chemical Co., Ltd 		58
Shenzhen Nexconn Pharmatechs Ltd 		58
Accela ChemBio Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
Fuxin Pharmaceutical 		58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		58
Finetech Industry Limited 		58
Hangzhou Huarong Pharm Co., Ltd. 		58
sgtlifesciences pvt ltd 		58

View Lastest Price from (R)-(+)-2-BENZYLOXYPROPIONIC ACID manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(R)-(+)-2-BENZYLOXYPROPIONIC ACID pictures 2025-09-25 (R)-(+)-2-BENZYLOXYPROPIONIC ACID
100836-85-9
 US $34.00-1.20 / kg 1kg 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
(R)-(+)-2-BENZYLOXYPROPIONIC ACID pictures 2020-01-13 (R)-(+)-2-BENZYLOXYPROPIONIC ACID
100836-85-9
 US $1.00 / KG 1KG 99% 100KG Career Henan Chemical Co

(R)-(+)-2-BENZYLOXYPROPIONIC ACID Spectrum

(R)-(+)-2-BENZYLOXYPROPIONIC ACID(100836-85-9)1HNMR

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O-BENZYL-D-LACTIC ACID (R)-(+)-2-BENZYLOXYPROPIONIC ACID (R)-(+)-2-(Benzyloxy)propionic acid[>=97.0% (HPLC)] (R)-(+)-O-Benzyllactic acid Propanoic acid, 2-(phenylMethoxy)-, (2R)- (2R)-2-(Benzyloxy)propionic acid (R)-2-(Benzyloxy)propanoic acid (2R)-2-(benzyloxy)propanoic acid (2R)-2-phenylmethoxypropanoic acid (R)-2-(Benzyloxy)propanoic acid ee 100836-85-9 Organic Building Blocks Asymmetric Synthesis Carboxylic Acids Chiral Building Blocks