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Saccharin sodium dihydrate

Saccharin sodium dihydrate
Saccharin sodium dihydrate structure
CAS No.
6155-57-3
Chemical Name:
Saccharin sodium dihydrate
Synonyms
o Dihydrate;SodiumSaccarrin;SODIUM SACCHARIN;SOLUBLE SACCHARIN;SodiuM Saccharin USP;SODIUM SACCHARINE USP;SODIUM SACCHARIN BP93;Saccharin sodium 98.0+;Saccharin sodium (2H2O);SODIUM SACCRINE GRANULER
CBNumber:
CB1115998
Molecular Formula:
C7H8NNaO4S
Formula Weight:
225.19
MOL File:
6155-57-3.mol

Saccharin sodium dihydrate Properties

Melting point:
> 300℃
Flash point:
>200°C
storage temp. 
2-8°C
solubility 
1000g/l
PH
6.0-7.5 (100g/l, H2O, 20℃)
Water Solubility 
Soluble in water. Slightly soluble in alcohol
Merck 
14,8311
InChIKey
BCWVKFPXENUOQA-UHFFFAOYSA-N
CAS DataBase Reference
6155-57-3(CAS DataBase Reference)
Indirect Additives used in Food Contact Substances
SODIUM SACCHARIN
EWG's Food Scores
1
SAFETY
  • Risk and Safety Statements
Risk Statements  22
Safety Statements  24/25
WGK Germany  2
RTECS  DE4375000
TSCA  Yes
HS Code  29350090
Toxicity LD50 orally in Rabbit: 14200 mg/kg

Saccharin sodium dihydrate price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.14114 Saccharin sodium salt dihydrate for synthesis. CAS 6155-57-3, pH 6.0 - 7.5 (100 g/l, H O, 20 °C)., for synthesis 6155-57-3 8141140100 $27.9 2020-08-18 Buy
Sigma-Aldrich 47839 Sodium Saccharin analytical standard 6155-57-3 1000 mg $22.3 2021-03-22 Buy
Sigma-Aldrich 1607040 Saccharin sodium salt dihydrate 6155-57-3 100mg $352.8 2018-11-20 Buy
TCI Chemical B0131 o-Sulfobenzimide Sodium Salt Dihydrate >98.0%(HPLC)(T) 6155-57-3 25g $27 2021-03-22 Buy
TCI Chemical B0131 o-Sulfobenzimide Sodium Salt Dihydrate >98.0%(HPLC)(T) 6155-57-3 500g $90 2021-03-22 Buy

Saccharin sodium dihydrate Chemical Properties,Uses,Production

Description

Saccharin sodium dihydrate is the sodium dihydrate form of saccharin, which belongs to the family of aromatic homomonocyclic compounds. It is an artificial sweetener that is hundreds times as sweet as sucrose. It is mainly used as a food additive to sweeten many products such as drinks, candies, cookies, and medicine. Saccharin is relatively safe for human beings without providing food energy and any nutritional value. It is also safe for diabetes patients to consume. 

Chemical Properties

dihydrate granular

Chemical Properties

Saccharin sodium occurs as a white, odorless or faintly aromatic, efflorescent, crystalline powder. It has an intensely sweet taste, with a metallic or bitter aftertaste that at normal levels of use can be detected by approximately 25% of the population. The aftertaste can be masked by blending saccharin sodium with other sweeteners. Saccharin sodium can contain variable amounts of water.

Uses

Sweetener (non-nutritive).

Production Methods

Saccharin is produced by the oxidation of o-toluene sulfonamide by potassium permanganate in a solution of sodium hydroxide. Acidification of the solution precipitates saccharin, which is then dissolved in water at 50℃ and neutralized by addition of sodium hydroxide. Rapid cooling of the solution initiates crystallization of saccharin sodium from the liquors.

brand name

Sucaryl (Ross).

Pharmaceutical Applications

Saccharin sodium is an intense sweetening agent used in beverages, food products, table-top sweeteners, and pharmaceutical formulations such as tablets, powders, medicated confectionery, gels, suspensions, liquids, and mouthwashes. It is also used in vitamin preparations.
Saccharin sodium is considerably more soluble in water than saccharin, and is more frequently used in pharmaceutical formulations. Its sweetening power is approximately 300–600 times that of sucrose. Saccharin sodium enhances flavor systems and may be used to mask some unpleasant taste characteristics.
Injection of saccharin sodium has been used to measure the armto- tongue circulation time.

Safety

There has been considerable controversy concerning the safety of saccharin and saccharin sodium in recent years; however, it is now generally regarded as a safe, intense sweetener. See Saccharin for further information.
The WHO has set a temporary acceptable daily intake of up to 2.5 mg/kg body-weight for saccharin, including its salts.(3) In the UK, the Committee on Toxicity of Chemicals in Food, Consumer Products, and the Environment (COT) has set an acceptable daily intake for saccharin and its salts (expressed as saccharin sodium) at up to 5 mg/kg body-weight.
LD50 (mouse, oral): 17.5 g/kg
LD50 (rat, IP): 7.1 g/kg
LD50 (rat, oral): 14.2 g/kg

storage

Saccharin sodium is stable under the normal range of conditions employed in formulations. Only when it is exposed to a high temperature (125℃) at a low pH (pH 2) for over 1 hour does significant decomposition occur. The 84% grade is the most stable form of saccharin sodium since the 76% form will dry further under ambient conditions. Solutions for injection can be sterilized by autoclave.
Saccharin sodium should be stored in a well-closed container in a dry place.

Incompatibilities

Saccharin sodium does not undergo Maillard browning.

Regulatory Status

Accepted for use as a food additive in Europe; ‘E954’ is applied to both saccharin and saccharin salts. Included in the FDA Inactive Ingredients Database (buccal and dental preparations; IM and IV injections; oral and topical preparations). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

References

https://en.wikipedia.org/wiki/Saccharin
https://pubchem.ncbi.nlm.nih.gov/compound/saccharin#section=Top

Saccharin sodium dihydrate Preparation Products And Raw materials

Raw materials

Preparation Products


Saccharin sodium dihydrate Suppliers

Global( 161)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Beijing Cooperate Pharmaceutical Co.,Ltd
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Henan Tianfu Chemical Co.,Ltd.
0371-55170693
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Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
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Hubei Jusheng Technology Co.,Ltd.
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View Lastest Price from Saccharin sodium dihydrate manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-10-20 Saccharin Sodium Dihydrate
6155-57-3
US $1.00 / g 10g 99% 20 tons Wuhan wingroup Pharmaceutical Co., Ltd
2021-09-14 Saccharin sodium dihydrate
6155-57-3
US $8700.00 / KG 1000KG 99% 1000tons Baoji Guokang Healthchem co.,ltd
2021-09-07 Saccharin sodium
6155-57-3
US $20.00 / Kg/Drum 25Kg/Drum 99.99% 1 ton per week Wuhan Mulei New Material Technology Co. Ltd

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