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2-Bromo-4'-methylacetophenone

2-Bromo-4'-methylacetophenone structure

CAS No.: 619-41-0

Chemical Name:: 2-Bromo-4'-methylacetophenone

Synonyms: NSC-63192;omega-Bro;ETHYL-P-TOLYLKETON;P-TOLYL ETHYL KETONE;Zolpidem Impurity 54;LABOTEST-BB LT00053050;p-Methylphenacyl bromide;2-bromo-1-p-tolylethanone;4-Methylphenacylbromide98%;Bromomethyl p-tolyl ketone

CBNumber:: CB1116041

Molecular Formula:: C9H9BrO

Molecular Weight:: 213.07

MDL Number:: MFCD00000203

MOL File:: 619-41-0.mol

MSDS File:: SDS

Last updated:2025-09-25 17:15:13

Product description	Number	Pack Size	Price
2-Bromo-4′-methylacetophenone 90%	159530	5g	$40.7
2-Bromo-4′-methylacetophenone 90%	159530	25g	$193
2-Bromo-4'-methylacetophenone >98.0%(GC)	B2107	5g	$26
2-Bromo-4'-methylacetophenone >98.0%(GC)	B2107	25g	$76
2-Bromo-4′-methylacetophenone 90%	159530	100g	$333
More product size

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2-Bromo-4'-methylacetophenone Properties

Melting point	45-49 °C(lit.)
Boiling point	238-239 °C(lit.)
Density	0.993 g/mL at 25 °C(lit.)
refractive index	n20/D 1.528(lit.)
Flash point	229 °F
storage temp.	2-8°C
solubility	Chloroform (Slightly), Ethyl Acetate
form	Crystalline Powder or Needles
color	White to light yellow
BRN	607041
Stability	Stable. Incompatible with strong oxidizing agents, strong bases.
InChI	InChI=1S/C9H9BrO/c1-7-2-4-8(5-3-7)9(11)6-10/h2-5H,6H2,1H3
InChIKey	KRVGXFREOJHJAX-UHFFFAOYSA-N
SMILES	C(=O)(C1=CC=C(C)C=C1)CBr
CAS DataBase Reference	619-41-0(CAS DataBase Reference)
FDA UNII	7DX9QRY7DP
NIST Chemistry Reference	Ethanone, 2-bromo-1-(4-methylphenyl)-(619-41-0)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-27-37/39

RIDADR

UN 2811

WGK Germany

Hazard Note

Irritant

HazardClass

6.1

PackingGroup

III

HS Code

29147000

Limited Quantities

5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)

Excepted Quantities

Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

NFPA 704

	1
2		0

2-Bromo-4'-methylacetophenone price More Price(36)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	159530	2-Bromo-4′-methylacetophenone 90%	619-41-0	5g	$40.7	2025-07-31	Buy
Sigma-Aldrich	159530	2-Bromo-4′-methylacetophenone 90%	619-41-0	25g	$193	2025-07-31	Buy
TCI Chemical	B2107	2-Bromo-4'-methylacetophenone >98.0%(GC)	619-41-0	5g	$26	2025-07-31	Buy
TCI Chemical	B2107	2-Bromo-4'-methylacetophenone >98.0%(GC)	619-41-0	25g	$76	2025-07-31	Buy
Sigma-Aldrich	159530	2-Bromo-4′-methylacetophenone 90%	619-41-0	100g	$333	2023-06-20	Buy

Product number	Packaging	Price	Buy
159530	5g	$40.7	Buy
159530	25g	$193	Buy
B2107	5g	$26	Buy
B2107	25g	$76	Buy
159530	100g	$333	Buy

2-Bromo-4'-methylacetophenone Chemical Properties,Uses,Production

Chemical Properties

White to light yellow crystal powder

Uses

2-Bromo-4′-methylacetophenone was used in the general fluorous thiol quenching method. It was also used in the preparation of hydroxyquinolinone and N-derivatized carboxamides.

General Description

2-Bromo-4′-methylacetophenone is an α-bromoketone.

Synthesis

622-97-9

619-41-0

General procedure: 4-methylstyrene (1 mmol) was dissolved in a solvent mixture of acetone (3 mL) and water (0.1 mL) at room temperature. Subsequently, dibromo-p-toluenesulfonamide (TsNBr2, 2.2 mmol) was slowly added to this solution. After the reaction was complete, sodium thiosulfate (~200 mg) was added to quench the reaction and stirring was continued for 10 minutes. The reaction mixture was extracted with ethyl acetate and the organic phase was dried over anhydrous sodium sulfate (Na2SO4) and subsequently concentrated under reduced pressure to remove the solvent. The crude product was purified by column chromatography on silica gel (230-400 mesh), the eluent being a mixed petroleum ether-ethyl acetate solvent, to give the final pure 2-bromo-4'-methylacetophenone.

References

[1] Tetrahedron Letters, 2015, vol. 56, # 2, p. 356 - 358
[2] Organic and Biomolecular Chemistry, 2016, vol. 14, # 48, p. 11389 - 11395
[3] Green Chemistry, 2013, vol. 15, # 8, p. 2175 - 2179
[4] Synlett, 2010, # 15, p. 2335 - 2339
[5] Organic Letters, 2015, vol. 17, # 11, p. 2704 - 2707

2-Bromo-4'-methylacetophenone synthesis

Synthesis of 2-Bromo-4'-methylacetophenone from 4-Ethynyltoluene

2-Bromo-4'-methylacetophenone Preparation Products And Raw materials

Raw materials

Benzene, 1-methyl-4-[1-(phenylmethoxy)ethyl]- (Z)-2-diazonio-1-(4-methylphenyl)ethenolate Benzenemethanol, α-(bromomethyl)-4-methyl- Benzene, 1-(1-bromoethenyl)-4-methyl- 1-Bromo-2-(4-methylphenyl)acetylene

2,2-DIBROMO-1-P-TOLYLETHANONE Acetone 4'-Methylacetophenone 1-(4-Methylphenyl)ethanol 4-Methylstyrene

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Preparation Products

3-(4-METHYLPHENYL)ISOXAZOL-5-AMINE 2-AMINO-4-(P-TOLYL)THIAZOLE 1-(4-bromophenyl)-2-chloroethan-1-one 3'-BROMO-4'-METHYLACETOPHENONE 2,2-DIBROMO-1-P-TOLYLETHANONE

2-Bromo-4'-methylacetophenone Suppliers

Global( 308)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8770	58
Sichuan Zhuoyu Yantang Technology Co., Ltd.	+8613288715578	sales@sichuanzyyt.com	China	12218	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	sales1@chuanghaibio.com	China	5251	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	+86-13017695106 +86-13676922317	jiuyitime@fdachem.com	China	16515	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29850	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10405	58
Nanjing Dolon Biotechnology Co.,Ltd.	18905173768	52513593@qq.com	CHINA	2972	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49975	58
Antai Fine Chemical Technology Co.,Limited	18503026267	info@antaichem.com	CHINA	9636	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	58
Sichuan Zhuoyu Yantang Technology Co., Ltd.	58
Hebei Chuanghai Biotechnology Co,.LTD	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	58
career henan chemical co	58
Shenzhen Nexconn Pharmatechs Ltd	58
Nanjing Dolon Biotechnology Co.,Ltd.	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Antai Fine Chemical Technology Co.,Limited	58

View Lastest Price from 2-Bromo-4'-methylacetophenone manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-11-10	2-Bromo-4'-methylacetophenone 619-41-0	US $0.00-0.00 / KG	1KG	99%	20 mt	Hebei Chuanghai Biotechnology Co., Ltd
2025-10-13	2-bromo-4'-methylacetophenone 619-41-0	US $2.20-8.80 / kg	1kg	99%	100kg	ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
2025-08-08	2-Bromo-4'-methylacetophenone 619-41-0	US $0.00 / KG	1KG	99%	50000KG/month	Sichuan Zhuoyu Yantang Technology Co., Ltd.

2-Bromo-4'-methylacetophenone
619-41-0
US $0.00-0.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

2-bromo-4'-methylacetophenone
619-41-0
US $2.20-8.80 / kg
99%
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

2-Bromo-4'-methylacetophenone
619-41-0
US $0.00 / KG
99%
Sichuan Zhuoyu Yantang Technology Co., Ltd.

2-Bromo-4'-methylacetophenone Spectrum

2-Bromo-4'-methylacetophenone(619-41-0)MS 2-Bromo-4'-methylacetophenone(619-41-0)¹HNMR 2-Bromo-4'-methylacetophenone(619-41-0)IR1 2-Bromo-4'-methylacetophenone(619-41-0)IR2 2-Bromo-4'-methylacetophenone(619-41-0)Raman

619-41-0(2-Bromo-4'-methylacetophenone)Related Search:

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2-Bromoacetophenone 4-(Trifluoromethyl)phenacyl bromide 2-BROMO-1-(2,4-DIMETHYLPHENYL)ETHAN-1-ONE Methyl bromide 2-BROMO-4'-PHENYLACETOPHENONE

2-BROMO-1-(3-CHLORO-4-METHYLPHENYL)PROPAN-1-ONE 4,4'-Bis(2-bromoacetyl)biphenyl Bromine

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P-TOLYL ETHYL KETONE ETHYL-P-TOLYLKETON LABOTEST-BB LT00053050 2-Bromo-p-methylacetophenone Acetophenone, 2-bromo-4'-methyl- alpha-Bromo-4-methylacetophenone alpha-Bromo-p-methylacetophenone omega-Bromo-p-methylacetophenone p-Methyl-alpha-bromoacetophenone p-Methyl-omega-bromoacetophenone p-Methylphenacyl bromide 4-Methylphenacylbromide98% 4-Methylphenacylbromide 98% 4'-Methyl-2-bromoacetophenone à-bromo-4-methylacetophenone 2-BROMO-4-METHYLACETACETOPHENONE 2-Bromo-1-(4-methylphenyl)ethan-1-one 2-Bromo-4'-methylacetophenone 2-bromo-1-p-tolylethanone a-Bromo-p-methylacetophenone Bromomethyl p-tolyl ketone 1-(Bromoacetyl)-4-methylbenzene 2-Bromo-1-(4-tolyl)ethanone NSC-63192 2-Bromo-4'-methylacetophenone,97% 2-Bromo-4-methylacetaphenone 4-(Bromoacetyl)toluene 4-Methylphenacyl Bromide 2-BroMo-4'-Methylacetophenone 90% 2-bromo-1-(p-tolyl)ethan-1-one JR-8309, 2-Bromo-4'-methylacetophenone, 97% omega-Bro 2-Bromo-4'-methylacetophenone> Ethanone, 2-bromo-1-(4-methylphenyl)- Zolpidem Impurity 54 2 - BROMINE - 4 '- METHYL ACETOPHENONE 2-Bromo-4′-methylacetophenone, 90%+ 619-41-0 Carbonyl Compounds C10 C9 Building Blocks Ketones Organic Building Blocks Aromatics Acetophenone series C9 Carbonyl Compounds Ketones Aromatic Acetophenones & Derivatives (substituted)