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5-O-Desmethyl Donepezil

CAS No.
120013-57-2
Chemical Name:
5-O-Desmethyl Donepezil
Synonyms
Donepezil Impurity 28;Donepezil Impurity 59;Donepezil 5-O-Desmethyl Imp;Donepezil 5-hydroxy Impurity;Donepezil 5-O-Desmethyl Impurity;1-Benzyl-4-[(5-hydroxy-6-methoxy-1-oxo-indan-2-yl)methylpiperidine;2-[(1-benzylpiperidin-4-yl)methyl]-5-hydroxy-6-methoxy-2,3-dihydroinden-1-one;2-((1-benzylpiperidin-4-yl)methyl)-5-hydroxy-6-methoxy-2,3-dihydro-1H-inden-1-one;1H-Inden-1-one, 2,3-dihydro-5-hydroxy-6-methoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-;2-((1-benzylpiperidin-4-yl)methyl)-5-hydroxy-6-methoxy-2,3-dihydro-1H-inden-1-one hydrochloride
CBNumber:
CB11175991
Molecular Formula:
C23H27NO3
Molecular Weight:
365.47
MDL Number:
MOL File:
120013-57-2.mol
MSDS File:
SDS
Last updated:2023-05-15 10:43:58

5-O-Desmethyl Donepezil Properties

Melting point 170-172°C
Boiling point 545.3±50.0 °C(Predicted)
Density 1.190±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly, Heated)
form Solid
pka 8.16±0.40(Predicted)
color White to Pale Brown
CAS DataBase Reference 120013-57-2
FDA UNII 56R452SD5N

5-O-Desmethyl Donepezil price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC D292010 5-O-DesmethylDonepezil 120013-57-2 5mg $350 2021-12-16 Buy
TRC D292010 5-O-DesmethylDonepezil 120013-57-2 2.5mg $185 2021-12-16 Buy
Biosynth Carbosynth FD21262 5-O-Desmethyl donepezil 120013-57-2 2mg $272.6 2021-12-16 Buy
Biosynth Carbosynth FD21262 5-O-Desmethyl donepezil 120013-57-2 1mg $149.9 2021-12-16 Buy
Biosynth Carbosynth FD21262 5-O-Desmethyl donepezil 120013-57-2 5mg $495.5 2021-12-16 Buy
Product number Packaging Price Buy
D292010 5mg $350 Buy
D292010 2.5mg $185 Buy
FD21262 2mg $272.6 Buy
FD21262 1mg $149.9 Buy
FD21262 5mg $495.5 Buy

5-O-Desmethyl Donepezil Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

A metabolite of Donepezil (D531750), an inhibitor of acetylcholinesterase.

Uses

A metabolite of Donepezil, an inhibitor of acetylcholinesterase

Definition

ChEBI: 5-O-desmethyldonepezil is a member of the class of piperidines that is donepezil in which the 5-methoxy group has been demethylated to the corresponding hydroxy derivative. It is metabolite of donepezil, a drug used in the treatment of dementia. It has a role as a drug metabolite. It is a member of piperidines, a cyclic ketone, an aromatic ether and a member of guaiacols.

5-O-Desmethyl Donepezil Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 37)Suppliers
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Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Standardpharm Co. Ltd.
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CR Corporation Lomited
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Hunan Jibang Biological Technology Co., LTD
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China National Standard Pharmaceutical Corporation Limited
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J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 94838 76
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32344 50
Shanghai TaoSu Biochemical Technology Co., Ltd. 021-33632979 info@tsbiochem.com China 8073 58
Cato Research Chemicals Inc. 020-81960175 min.he@cato-chem.com China 1958 55
ChemStrong Scientific Co.,Ltd 0755-66853366 15920483169 sales@chem-strong.com China 17944 56
1-Benzyl-4-[(5-hydroxy-6-methoxy-1-oxo-indan-2-yl)methylpiperidine 2-((1-benzylpiperidin-4-yl)methyl)-5-hydroxy-6-methoxy-2,3-dihydro-1H-inden-1-one 2-((1-benzylpiperidin-4-yl)methyl)-5-hydroxy-6-methoxy-2,3-dihydro-1H-inden-1-one hydrochloride Donepezil 5-O-Desmethyl Impurity Donepezil Impurity 28 Donepezil 5-O-Desmethyl Imp 2-[(1-benzylpiperidin-4-yl)methyl]-5-hydroxy-6-methoxy-2,3-dihydroinden-1-one 1H-Inden-1-one, 2,3-dihydro-5-hydroxy-6-methoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]- Donepezil Impurity 59 Donepezil 5-hydroxy Impurity 120013-57-2 Heterocycles Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals