Brofaromine
- CAS No.
- 63638-91-5
- Chemical Name:
- Brofaromine
- Synonyms
- 4-(7-bromo-5-methoxybenzofuran-2-yl)piperidine;Piperidine, 4-(7-bromo-5-methoxy-2-benzofuranyl)-;4-(7-Bromo-5-methoxy-1-benzofuran-2-yl)piperidine
- CBNumber:
- CB11178149
- Molecular Formula:
- C14H16BrNO2
- Molecular Weight:
- 310.19
- MDL Number:
- MOL File:
- 63638-91-5.mol
- MSDS File:
- SDS
| Boiling point | 404.0±45.0 °C(Predicted) |
|---|---|
| Density | 1.386±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO: 250 mg/mL (805.96 mM) |
| pka | 9.99±0.10(Predicted) |
| FDA UNII | 6WV4B8Q07H |
Brofaromine price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-6637 | Brofaromine 98.55% | 63638-91-5 | 5mg | $245 | 2021-12-16 | Buy |
| ChemScene | CS-6637 | Brofaromine 98.55% | 63638-91-5 | 10mg | $395 | 2021-12-16 | Buy |
| ChemScene | CS-6637 | Brofaromine 98.55% | 63638-91-5 | 50mg | $980 | 2021-12-16 | Buy |
| ChemScene | CS-6637 | Brofaromine 98.55% | 63638-91-5 | 100mg | $1500 | 2021-12-16 | Buy |
Brofaromine Chemical Properties,Uses,Production
Biological Activity
Brofaromine (CGP 11305A) is a monoamine oxidase (MAO) inhibitor, inhibits MAO-A with IC50 of 0.2 μM.
in vitro
In order to assess whether the protective effect is related to the inhibition of the MAO-A or due to another mechanism, the effect of Brofaromine (CGP 11305A, BRO) is determined on the activity of MAO-A in cultured cortical cells. It shows, firstly, that cultured cortical cells have a significant MAO-A activity, and secondly, that Brofaromine inhibits the enzyme in a concentration-dependent manner. The IC 50 is 0.19 μM for Brofaromine . Hill coefficient is 0.96. The enzyme is almost completely inhibited at 10 μM . Brofaromine inhibits MAO-A activity of our cultured cortical cells in a concentration-dependent manner. The IC 50 range of Brofaromine is 0.01 μM to 0.1 μM.
target
IC50: 0.2 μM (MAO-A)
Brofaromine Preparation Products And Raw materials
Raw materials
Preparation Products
Brofaromine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Shenzhen Regent Biochemical Technology Co., Ltd. | 0755-0755-85201366 18938635012 | sales@regentsciences.com | China | 9287 | 58 |
| Jiangsu yize medical technology co. LTD | 18550739526 | 23903480@qq.com | China | 5841 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223 | psaitong@jm-bio.com | China | 29834 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24131 | 58 |