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Butriptyline

CAS No.
35941-65-2
Chemical Name:
Butriptyline
Synonyms
Butriptylene;Butriptyline (1.0 mg/mL in Methanol);10,11-Dihydro-N,N,-trimethyl-5H-dibenzo[a,d]cycloheptene-5-propylamine;10,11-Dihydro-N,N,-trimethyl-5H-dibenzo[a,d]cycloheptene-5-propanamine;5H-Dibenzo[a,d]cycloheptene-5-propanamine, 10,11-dihydro-N,N,β-trimethyl-;3-(10,11-Dihydro-5H-dibenzo[A,D][7]annulen-5-yl)-N,N,2-trimethylpropan-1-amine
CBNumber:
CB11178200
Molecular Formula:
C21H27N
Molecular Weight:
293.45
MDL Number:
MFCD00865393
MOL File:
35941-65-2.mol
MSDS File:
SDS
Last updated:2023-05-04 17:34:38

Butriptyline Properties

Boiling point 180-1850C
Density 0.9665 (rough estimate)
refractive index 1.4900 (estimate)
pka 9.50±0.28(Predicted)
CAS DataBase Reference 35941-65-2
FDA UNII Z22441975X

SAFETY

Risk and Safety Statements

RIDADR  1851
HazardClass  6.1(b)
PackingGroup  III

Butriptyline price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC B690050 Butriptyline 35941-65-2 1mg $155 2021-12-16 Buy
American Custom Chemicals Corporation API0000435 BUTRIPTYLINE 95.00% 35941-65-2 1MG $739.2 2021-12-16 Buy
American Custom Chemicals Corporation API0000435 BUTRIPTYLINE 95.00% 35941-65-2 10MG $2867.55 2021-12-16 Buy
Product number Packaging Price Buy
B690050 1mg $155 Buy
API0000435 1MG $739.2 Buy
API0000435 10MG $2867.55 Buy

Butriptyline Chemical Properties,Uses,Production

Chemical Properties

Oil

Originator

Evadyne,Ayerst,UK,1975

Uses

Antidepressant

Definition

ChEBI: Butriptyline is an organic tricyclic compound.

Manufacturing Process

A solution of dibenzo[a,e]cycloheptadiene in anhydrous xylene is added in a dropwise fashion with stirring to a suspension of sodium hydride in refluxing anhydrous xylene. The mixture is heated at reflux for two hours with continual agitation and there is then added dropwise a solution of 2-methyl-3- dimethylaminopropyl chloride in an equal volume of xylene. The mixture is then heated for fifteen hours, after which time it is cooled and decomposed by the cautious addition of ice water. The layers are separated and the aqueous layer extracted with ether. The combined organic layers are next extracted with 10% hydrochloric acid and the acidic extracts then rendered alkaline by the addition of ammonium hydroxide. The precipitated oil is extracted three times with chloroform. The chloroform extracts are dried and concentrated in vacuo, the residue being distiiled to yield the product.

Therapeutic Function

Antidepressant

Butriptyline Preparation Products And Raw materials

Raw materials

Preparation Products

Butriptyline Suppliers

Global( 9)Suppliers
Supplier Tel Email Country ProdList Advantage
Career Henan Chemica Co
+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32344 50
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 sales@rrkchem.com China 55717 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44941 58
10,11-Dihydro-N,N,-trimethyl-5H-dibenzo[a,d]cycloheptene-5-propanamine 10,11-Dihydro-N,N,-trimethyl-5H-dibenzo[a,d]cycloheptene-5-propylamine Butriptylene 3-(10,11-Dihydro-5H-dibenzo[A,D][7]annulen-5-yl)-N,N,2-trimethylpropan-1-amine 5H-Dibenzo[a,d]cycloheptene-5-propanamine, 10,11-dihydro-N,N,β-trimethyl- Butriptyline (1.0 mg/mL in Methanol) 35941-65-2 Amines Intermediates & Fine Chemicals Pharmaceuticals