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Acetamide, N,N'-trans-1,4-cyclohexanediylbis[2-(4-chloro-3-fluorophenoxy)-

Acetamide, N,N'-trans-1,4-cyclohexanediylbis[2-(4-chloro-3-fluorophenoxy)- structure

CAS No.: 1628478-15-8

Chemical Name:: Acetamide, N,N'-trans-1,4-cyclohexanediylbis[2-(4-chloro-3-fluorophenoxy)-

Synonyms: ISR-IN-1;trans-isrib A17;Acetamide, N,N'-trans-1,4-cyclohexanediylbis[2-(4-chloro-3-fluorophenoxy)-;N,N'-(trans-Cyclohexane-1,4-diyl)bis(2-(4-chloro-3-fluorophenoxy)acetamide)

CBNumber:: CB112216511

Molecular Formula:: C22H22Cl2F2N2O4

Molecular Weight:: 487.32

MDL Number:

MOL File:: 1628478-15-8.mol

Last updated:2025-04-30 08:50:00

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Acetamide, N,N'-trans-1,4-cyclohexanediylbis[2-(4-chloro-3-fluorophenoxy)- Properties

Boiling point	705.1±60.0 °C(Predicted)
Density	1.40±0.1 g/cm3(Predicted)
pka	13.44±0.40(Predicted)
form	Solid
color	Off-white to light yellow

Acetamide, N,N'-trans-1,4-cyclohexanediylbis[2-(4-chloro-3-fluorophenoxy)- Chemical Properties,Uses,Production

Uses

ISR-IN-1 (Compound 48) is an inhibitor of the integrated stress response (EC50: 0.6 nM)[1].

References

[1] Hearn BR, et al. Structure-Activity Studies of Bis-O-Arylglycolamides: Inhibitors of the Integrated Stress Response. ChemMedChem. 2016 Apr 19;11(8):870-80. DOI:10.1002/cmdc.201500483

Acetamide, N,N'-trans-1,4-cyclohexanediylbis[2-(4-chloro-3-fluorophenoxy)- Preparation Products And Raw materials

Raw materials

Preparation Products

Acetamide, N,N'-trans-1,4-cyclohexanediylbis[2-(4-chloro-3-fluorophenoxy)- Suppliers

Global( 15)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Wuhan Nutra Biotechnology Co.,Ltd	+8617786394783	nutrabiotech@outlook.com	China	300	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32275	58
Shanghai YuanYe Biotechnology Co., Ltd.	021-61312847; 18021002903	3008007409@qq.com	China	71826	60
Tianjin Kailiqi Biotechnology Co., Ltd.	15076683720	klq@cw-bio.com	China	6448	55
Shanghai Chaolan Chemical Technology Center	021-QQ：65489617 15618227136	Sales@ATKchemical.com	China	9348	58
Bide Pharmatech Ltd.	400-1647117 13681763483	product02@bidepharm.com	China	62321	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24875	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	11973	58
Hubei wei shi reagent group ltd., company	027-59101766 13125137661	2853877621@qq.com	China	8000	58

Supplier	Advantage
Wuhan Nutra Biotechnology Co.,Ltd	58
ATK CHEMICAL COMPANY LIMITED	60
TargetMol Chemicals Inc.	58
Shanghai YuanYe Biotechnology Co., Ltd.	60
Tianjin Kailiqi Biotechnology Co., Ltd.	55
Shanghai Chaolan Chemical Technology Center	58
Bide Pharmatech Ltd.	58
TargetMol Chemicals Inc.	58
Shanghai Yifei Biotechnology Co. , Ltd.	58
Hubei wei shi reagent group ltd., company	58

View Lastest Price from Acetamide, N,N'-trans-1,4-cyclohexanediylbis[2-(4-chloro-3-fluorophenoxy)- manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-04-30	trans-isrib A17 1628478-15-8	US $36.00-133.00 / mg		98.17%	10g	TargetMol Chemicals Inc.
	2024-11-01	trans-isrib A17 1628478-15-8	US $250.00 / box	1box	98	100	Wuhan Nutra Biotechnology Co.,Ltd

trans-isrib A17
1628478-15-8
US $36.00-133.00 / mg
98.17%
TargetMol Chemicals Inc.

trans-isrib A17
1628478-15-8
US $250.00 / box
98
Wuhan Nutra Biotechnology Co.,Ltd

Acetamide, N,N'-trans-1,4-cyclohexanediylbis[2-(4-chloro-3-fluorophenoxy)- Spectrum

Acetamide, N,N'-trans-1,4-cyclohexanediylbis[2-(4-chloro-3-fluorophenoxy)-(1628478-15-8)¹HNMR

Acetamide, N,N'-trans-1,4-cyclohexanediylbis[2-(4-chloro-3-fluorophenoxy)- trans-isrib A17 N,N'-(trans-Cyclohexane-1,4-diyl)bis(2-(4-chloro-3-fluorophenoxy)acetamide) ISR-IN-1 1628478-15-8 C22H22Cl2F2N2O4