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epothilone E

CAS No.
201049-37-8
Chemical Name:
epothilone E
Synonyms
epothilone E;epothilone E USP/EP/BP;[4S,7R,8S,9S,13R,14S,16S(E)]-13,14-Epoxy-4,8-dihydroxy-5,5,7,9-tetramethyl-16-[2-[2-(hydroxymethyl)thiazol-4-yl]-1-methylvinyl]-1-oxacyclohexadecane-2,6-dione;(1R,5S,6S,7R,10S,14S,16S)-6,10-dihydroxy-14-[(E)-1-[2-(hydroxymethyl)-1,3-thiazol-4-yl]prop-1-en-2-yl]-5,7,9,9-tetramethyl-13,17-dioxabicyclo[14.1.0]heptadecane-8,12-dione;4,17-Dioxabicyclo[14.1.0]heptadecane-5,9-dione, 7,11-dihydroxy-3-[(1E)-2-[2-(hydroxymethyl)-4-thiazolyl]-1-methylethenyl]-8,8,10,12-tetramethyl-, (1S,3S,7S,10R,11S,12S,16R)-
CBNumber:
CB11311786
Molecular Formula:
C26H39NO7S
Molecular Weight:
509.66
MDL Number:
MFCD19982657
MOL File:
201049-37-8.mol
Last updated:2023-07-14 17:47:59

epothilone E Properties

Boiling point 715.5±60.0 °C(Predicted)
Density 1.187±0.06 g/cm3(Predicted)
pka 13.15±0.10(Predicted)
FDA UNII UK5H6YZZ8A

epothilone E Chemical Properties,Uses,Production

Uses

Epothilone E is a related compound of Epothilones, which are a novel class of antineoplastic agents with antitubulin activity. In addition, Epothilones utilize a similar mechanism of action to that of taxanes and are less susceptible to multidrug resistance caused by P-glycoprotein. Studies showed that Epothilones exhibit antitumor activity against human cancer cells that are taxane-resistant.

epothilone E Preparation Products And Raw materials

Raw materials

Preparation Products

epothilone E Suppliers

Global( 15)Suppliers
Supplier Tel Email Country ProdList Advantage
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22968 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 29271 58
Accendatech Co., LTD. 022-83718541 022-83718543 chuanjiang.qiu@accendatech.com China 332 58
Shanghai Witofly Chemical Co.,Ltd sales@witofly.com China 2867 52
Zhengzhou Acme Chemical Co., Ltd. 0371-0371-55629727 13323845623 2885676761@qq.com China 9859 58
Hubei widely chemical technology Co., Ltd. 027-83991130 18627774460 1718093273@QQ.COM China 1892 58
Shanghai Linka Biotechnology Co., Ltd. 15901858719 2126935757@qq.com China 311 55
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 sales@rrkchem.com China 55717 58
cjbscvictory 13348960310 13348960310 3003867561@qq.com China 9946 58
Tianjin Shangde Medicine Edge Technology Co., Ltd 13370460931 sales@accendatech.com China 11 58

View Lastest Price from epothilone E manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
epothilone E USP/EP/BP pictures 2021-07-05 epothilone E USP/EP/BP
201049-37-8
US $1.10 / g 1g 99.9% 100 Tons Min Dideu Industries Group Limited
epothilone E [4S,7R,8S,9S,13R,14S,16S(E)]-13,14-Epoxy-4,8-dihydroxy-5,5,7,9-tetramethyl-16-[2-[2-(hydroxymethyl)thiazol-4-yl]-1-methylvinyl]-1-oxacyclohexadecane-2,6-dione (1R,5S,6S,7R,10S,14S,16S)-6,10-dihydroxy-14-[(E)-1-[2-(hydroxymethyl)-1,3-thiazol-4-yl]prop-1-en-2-yl]-5,7,9,9-tetramethyl-13,17-dioxabicyclo[14.1.0]heptadecane-8,12-dione 4,17-Dioxabicyclo[14.1.0]heptadecane-5,9-dione, 7,11-dihydroxy-3-[(1E)-2-[2-(hydroxymethyl)-4-thiazolyl]-1-methylethenyl]-8,8,10,12-tetramethyl-, (1S,3S,7S,10R,11S,12S,16R)- epothilone E USP/EP/BP 201049-37-8