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trimethylcolchicinic acid methyl ether

CAS No.
3476-50-4
Chemical Name:
trimethylcolchicinic acid methyl ether
Synonyms
NSC 201400;Deacetylcolchicine;Desacetylcolchicine;Colchicine Impurity 22;(-)-7-Deacetylcolchicine;(S)-N-Deacetyl Colchicine;(-)-N-Deacetyl Colchicine;Colchicine N-Desacetyl (S)-Isomer;trimethylcolchicinic acid methyl ether;7-AMino-6,7-dihydro-1,2,3,10-tetraMethoxy-benzo[a]heptalen-9(5H)-one
CBNumber:
CB11317339
Molecular Formula:
C20H23NO5
Molecular Weight:
357.4
MDL Number:
MOL File:
3476-50-4.mol
Last updated:2023-06-08 09:03:09

trimethylcolchicinic acid methyl ether Properties

Boiling point 490.03°C (rough estimate)
Density 1.2532 (rough estimate)
refractive index 1.5614 (estimate)
storage temp. -20°C Freezer, Under Inert Atmosphere
solubility DMSO: 25mg/mL; Ethanol: 25mg/mL
form A crystalline solid
pka 8.62±0.40(Predicted)
FDA UNII 2IAP3WIO1P

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS05,GHS06,GHS08
Signal word  Danger
Hazard statements  H300-H318-H340
Precautionary statements  P201-P202-P264-P270-P280-P301+P310-P321-P330-P305+P351+P338-P308+P313-P405-P501
NFPA 704
0
4 0

trimethylcolchicinic acid methyl ether price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 21697 N-Deacetylcolchicine 3476-50-4 1mg $32 2024-03-01 Buy
Cayman Chemical 21697 N-Deacetylcolchicine 3476-50-4 5mg $116 2024-03-01 Buy
Cayman Chemical 21697 N-Deacetylcolchicine 3476-50-4 10mg $199 2024-03-01 Buy
Cayman Chemical 21697 N-Deacetylcolchicine 3476-50-4 25mg $343 2024-03-01 Buy
TRC D198920 (S)-N-DeacetylColchicine 3476-50-4 100mg $685 2021-12-16 Buy
Product number Packaging Price Buy
21697 1mg $32 Buy
21697 5mg $116 Buy
21697 10mg $199 Buy
21697 25mg $343 Buy
D198920 100mg $685 Buy

trimethylcolchicinic acid methyl ether Chemical Properties,Uses,Production

Chemical Properties

Yellow Solid

Uses

An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.

Definition

ChEBI: Deacetylcolchicine is a carbotricyclic compound, an alkaloid and a member of acetamides.

trimethylcolchicinic acid methyl ether Preparation Products And Raw materials

trimethylcolchicinic acid methyl ether Suppliers

Global( 31)Suppliers
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trimethylcolchicinic acid methyl ether (S)-7-Amino-6,7-dihydro-1,2,3,10-tetramethoxybenzo[a]heptalen-9(5H)-one Deacetylcolchicine Desacetylcolchicine (S)-N-Deacetyl Colchicine (-)-7-Deacetylcolchicine (7S)-7-AMino-6,7-dihydro-1,2,3,10-tetraMethoxy-benzo[a]heptalen-9(5H)-one NSC 201400 7-AMino-6,7-dihydro-1,2,3,10-tetraMethoxy-benzo[a]heptalen-9(5H)-one (7S)-7-Amino-1,2,3,10-Tetramethoxy-6,7-Dihydro-5H-Benzo[g]Heptalen-9-One Colchicine N-Desacetyl (S)-Isomer Benzo[a]heptalen-9(5H)-one, 7-amino-6,7-dihydro-1,2,3,10-tetramethoxy-, (7S)- (S)-7-Amino-1,2,3,10-tetramethoxy-6,7-dihydrobenzo[a]heptalen-9(5H)-one (-)-N-Deacetyl Colchicine Colchicine Impurity 22 3476-50-4 Amines Chiral Reagents Heterocycles Amines, Chiral Reagents, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals Inhibitors Intermediates & Fine Chemicals Pharmaceuticals