ChemicalBook
Chinese Japanese Germany Korea

4'-Methoxyacetophenone

Identification Description Regulatory Status Usage Natural occurrence
4'-Methoxyacetophenone
4'-Methoxyacetophenone structure
CAS No.
100-06-1
Chemical Name:
4'-Methoxyacetophenone
Synonyms
Epenone;Novatone;Vananote;VANATONE;NSC 5601;FEMA 2005;Linarodin;AKOS 90580;Acetanisol;NSC 209523
CBNumber:
CB1132155
Molecular Formula:
C9H10O2
Formula Weight:
150.17
MOL File:
100-06-1.mol

4'-Methoxyacetophenone Properties

Melting point:
36-38 °C(lit.)
Boiling point:
152-154 °C26 mm Hg(lit.)
Density 
1.08
FEMA 
2005 | ACETANISOLE
refractive index 
1.5470 (estimate)
Flash point:
>230 °F
storage temp. 
Store below +30°C.
solubility 
H2O: soluble2.474g/L at 20°C
form 
Crystals or Crystalline Powder
color 
White
Water Solubility 
insoluble
Sensitive 
Light Sensitive
JECFA Number
810
BRN 
742313
InChIKey
NTPLXRHDUXRPNE-UHFFFAOYSA-N
CAS DataBase Reference
100-06-1(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS)
ACETANISOLE
NIST Chemistry Reference
Acetophenone, 4'-methoxy-(100-06-1)
EPA Substance Registry System
4'-Methoxyacetophenone (100-06-1)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H302
Precautionary statements  P264-P280g-P301+P312a-P321-P332+P313-P501a-P301+P312+P330
Hazard Codes  Xn
Risk Statements  22-38-36/38-20/21/22
Safety Statements  37-37/39-26-36
WGK Germany  2
RTECS  AM9240000
TSCA  Yes
HS Code  29145000
Toxicity The acute oral LD50 value in rats was reported as 1.72 g/kg (1.47-1.97 g/kg) (Moreno, 1973). The acute dermal LD50 value in rabbits was reported as > 5 g/kg (Moreno, 1973).
NFPA 704
0
1 0

4'-Methoxyacetophenone price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 117374 4′-Methoxyacetophenone 99% 100-06-1 5g $26.4 2020-08-18 Buy
Sigma-Aldrich 117374 4′-Methoxyacetophenone 99% 100-06-1 1kg $122 2020-08-18 Buy
TCI Chemical M0105 4'-Methoxyacetophenone >99.0%(GC) 100-06-1 25g $22 2020-06-24 Buy
TCI Chemical M0105 4'-Methoxyacetophenone >99.0%(GC) 100-06-1 500g $133 2020-06-24 Buy
Alfa Aesar A11162 4'-Methoxyacetophenone, 99% 100-06-1 25g $16.7 2020-06-24 Buy

4'-Methoxyacetophenone Chemical Properties,Uses,Production

Identification

CAS.No.: 
100-06-1 
FL.No.: 
7.038
FEMA.No.: 
2005
NAS.No.: 
2005
CoE.No.: 
570
EINECS.No.: 
202-815-9 
JECFA.No.: 
810
 
 

Description

Yellowish-white crystals with an odor similar to that of p-methylacetopheneone, suggestive of hawthorn and floral note of heliotrope, possessing a bitter and unpleasant taste. Useful in vanilla, nut, tobacco and butter flavors.

Regulatory Status

CoE: Approved. Bev.: 10 ppm; Food: 20 ppm
FDA: 21 CFR 172.515
FDA (other): n/a
JECFA: ADI: Acceptable. No safety concern at current levels of intake when used as a flavoring agent (2001).

Usage

Reported uses (ppm): (FEMA, 1994)
Food Category 
Usual 
Max. 
Alcoholic.beverages 
0.0001
0.0001
Baked.goods 
1.5
2
Chewing.gum 
110
110
Frozen.dairy 
1
2
Gelatins,.puddings 
0.2
0.2
Hard.candy 
278.3
335
Meat.products 
100
100
Nonalcoholic.beverages 
7.8
150
Soft.candy 
2.1
31

Natural occurrence

Reported found in European cranberry (Vaccinium oxycoccus L.), guava fruit (Psidium guajava L.), Vitis labrusca L., tomato, anise (Pimpinella anisum L.), mentha oils, grilled and roasted beef, sherry, cloudberry (Rubus chamaemorus L.), salted and pickled plums, Illicium verum and black chokeberry (Aronia melanocarpa ell.).

Chemical Properties

WHITE CRYSTALS OR CRYSTALLINE POWDER

Chemical Properties

4-Methoxyacetophenone occurs in anise oil. It forms white crystals (mp 38°C) with a sweet odor, reminiscent of hawthorn. 4-Methoxyacetophenone is prepared by Friedel–Crafts acetylation of anisole. A modern process uses ??-zeolites as Friedel–Crafts catalysts in combination with a continuous flow technology. 4-Methoxyacetophenone is used in soap perfumes

Chemical Properties

Yellowish-white crystals with an odor similar to that of p-methylacetopheneone, suggestive of hawthorn and floral note of heliotrope, possessing a bitter and unpleasant taste. Useful in vanilla, nut, tobacco and butter flavors

Occurrence

Reported found in European cranberry (Vaccinium oxycoccus L.), guava fruit (Psidium guajava L.), Vitis labrusca L., tomato, anise (Pimpinella anisum L.), mentha oils, grilled and roasted beef, sherry, cloudberry (Rubus chamaemorus L.), salted and pickled plums, Illicium verum and black chokeberry (Aronia melanocarpa ell.).

Uses

4'-Methoxyacetophenone is a solid, pale yellow flavoring agent with a hawthornlike odor. It is soluble in most fixed oils and propylene glycol, and it is insoluble in glycerin and mineral oil. It is obtained by chemical synthesis. This flavoring substance or its adjuvant may be safely used in food in the minimum quantity required to produce its intended flavor. It can be used alone or in combination with other flavoring substances or adjuvants. It is also termed p-methoxyacetophenone.

Uses

Perfumery (for floral odors), flavoring.

Definition

ChEBI: A member of the class of acetophenones that is acetophenone substituted by a methoxy group at position 4.

Preparation

From anisole and acetyl chloride in the presence of aluminum chloride and carbon disulfide; from anisole and acetic acid in the presence of boron trifluoride.

Taste threshold values

Taste characteristics at 10 ppm: sweet, anisic, fruity, cherry with powdery vanilla nuances.

Synthesis Reference(s)

The Journal of Organic Chemistry, 46, p. 5414, 1981 DOI: 10.1021/jo00339a036
Synthetic Communications, 26, p. 291, 1996
Tetrahedron Letters, 35, p. 9471, 1994

Safety Profile

Moderately toxic by ingestion. Human systemic effects by inhalation: pulse rate increase without fall in blood pressure and blood pressure elevation. A skin irritant. Flammable liquid. When heated to decomposition it emits acrid smoke and irritating fumes. See also KETONES.

Purification Methods

Crystallise the ketone from diethyl ether/pet ether. [Beilstein 8 IV 340.]

4'-Methoxyacetophenone Preparation Products And Raw materials

Raw materials

Preparation Products


4'-Methoxyacetophenone Suppliers

Global( 366)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21848 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22623 55
Shanghai Time Chemicals CO., Ltd.
+86-021-57951555
+86-021-57951555 jack.li@time-chemicals.com CHINA 1365 55
Speranza Chemical Co., Ltd.
+8618688942810
+86-755-33122716 sophieliu@speranzachem.com CHINA 367 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30037 58
Hebei Huanhao Biotechnology Co., Ltd.
+8618034552304 +86 18034552304
86-0311-83975816 cathylee@hbhuanhao.com CHINA 755 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 linda@hubeijusheng.com CHINA 28230 58
Haihang Industry Co.,Ltd
86-531-88032799
+86 531 8582 1093 export@haihangchem.com CHINA 10426 58
Hebei Guanlang Biotechnology Co., Ltd.
+8619930503282 whatapp+8619930503282
86-0311-66562153 sales3@crovellbio.com CHINA 1321 58
Cangzhou Wanyou New Material Technology Co.,Ltd
18631714998
sales@czwytech.com CHINA 914 58

View Lastest Price from 4'-Methoxyacetophenone manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2020-08-27 4'-Methoxyacetophenone
100-06-1
US $30.00 / KG 1KG 99.9% 10tons Hebei Runbin Biotechnology Co. LTD
2020-04-16 Acetanisole
100-06-1
US $1.00 / 公斤 10g 99% 20tons Hebei Huanhao Biotechnology Co., Ltd.
2019-05-28 4'-Methoxyacetophenone 100-06-1 kf-wang(at)kf-chem.com
100-06-1
US $10.00 / Kg/Drum 1g 99.8% 20000 Hebei Aicrowe Biotech Co., Ltd

4'-Methoxyacetophenone Spectrum


100-06-1(4'-Methoxyacetophenone)Related Search:


Copyright 2017 © ChemicalBook. All rights reserved