2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
- CAS No.
- 124489-20-9
- Chemical Name:
- 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
- Synonyms
- N-OH-PHIP;N2-OH-PhIP;N-HYDROXY-PHIP;N-HYDROXY-2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE;2-(Hydroxyamino)-1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridine;1-Methyl-2-(hydroxyamino)-6-phenyl-1H-imidazo[4,5-b]pyridine;N-(1-methyl-6-phenylimidazo[4,5-b]pyridin-2-yl)hydroxylamine;N-(1-Methyl-6-phenyl-1H-imidazo[4,5-b]pyridine-2-yl)hydroxyamine;2H-Imidazo[4,5-b]pyridin-2-one, 1,3-dihydro-1-methyl-6-phenyl-, oxime
- CBNumber:
- CB11325833
- Molecular Formula:
- C13H12N4O
- Molecular Weight:
- 240.26
- MDL Number:
- MFCD00870431
- MOL File:
- 124489-20-9.mol
| Boiling point | 421.7±55.0 °C(Predicted) |
|---|---|
| Density | 1.35±0.1 g/cm3(Predicted) |
| pka | 11.70±0.40(Predicted) |
| FDA UNII | JC2M95KK23 |
2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine Chemical Properties,Uses,Production
Uses
2-Hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine is a mutagenic metablite of PhIP. PhIP is the most abundant mutagenic heterocyclic amine in cooked foods. Studies have shown the activation of 2-Hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in the formation of PhIP adducts and 5-OH-PhIP.
Definition
ChEBI: N-hydroxy-PhIP is an imidazopyridine that is 1H--imidazo[4,5-b]pyridine which is substituted at positions 1, 2, and 6 by methyl, hydoxyamino, and phenyl groups, respectively. The active metabolite of the dietary carcinogen PhIP. It has a role as a carcinogenic agent, a mutagen, a genotoxin, a human xenobiotic metabolite, a mouse metabolite, a rat metabolite and a neurotoxin. It is an imidazopyridine and a hydroxylamine. It is functionally related to a PhIP.
2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine Preparation Products And Raw materials
2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
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| DC Chemicals | 021-58447131 13564518121 | sales@dcchemicals.com | China | 9414 | 58 |
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| Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd | 024-024-88590548 18341751992 | 757984502@qq.com | China | 888 | 58 |
| Nanjing Tengyi Biotechnology Co., Ltd | 025-58851786 17714337195 | sales@tybiochem.com | China | 4257 | 58 |