ChemicalBook >> CAS DataBase List >>Ethyl 4,4,4-trifluoroacetoacetate
Ethyl 4,4,4-trifluoroacetoacetate
- CAS No.
- 372-31-6
- Chemical Name:
- Ethyl 4,4,4-trifluoroacetoacetate
- Synonyms
- ETHYL 4,4,4-TRIFLUORO-3-OXOBUTANOATE;ETHYL TRIFLUOROACETOACETATE;ETFAA;4,4,4-trifL;AKOS B020306;uoroacetoacetate;TIMTEC-BB SBB008825;Ethyl 4,4,4-trifluor;4-trifluoroacetoacetate;Ethyl 4,4,4-trifluoroaceto
- CBNumber:
- CB1133091
- Molecular Formula:
- C6H7F3O3
- Molecular Weight:
- 184.11
- MDL Number:
- MFCD00000424
- MOL File:
- 372-31-6.mol
- MSDS File:
- SDS
Last updated:2025-01-27 09:38:02
Melting point | -39 °C |
---|---|
Boiling point | 129-130 °C(lit.) |
Density | 1.259 g/mL at 25 °C(lit.) |
vapor pressure | 8hPa at 20℃ |
refractive index |
n |
Flash point | 84 °F |
storage temp. | Sealed in dry,Room Temperature |
solubility | 10g/l |
form | Liquid |
pka | 7.76±0.10(Predicted) |
Specific Gravity | 1.259 (20/4℃) |
color | Clear colorless to slightly yellow |
PH | 6.2 (10g/l, H2O, 20℃) |
Water Solubility | 10 g/L (20 ºC) |
BRN | 608353 |
InChIKey | OCJKUQIPRNZDTK-UHFFFAOYSA-N |
CAS DataBase Reference | 372-31-6(CAS DataBase Reference) |
FDA UNII | KM9XB46R5T |
NIST Chemistry Reference | Butanoic acid, 4,4,4-trifluoro-3-oxo-, ethyl ester(372-31-6) |
EPA Substance Registry System | Ethyl 4,4,4-trifluoroacetoacetate (372-31-6) |
UNSPSC Code | 12352100 |
NACRES | NA.22 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() ![]() GHS02,GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H226-H302-H412 | |||||||||
Precautionary statements | P210-P273-P301+P312+P330 | |||||||||
Hazard Codes | Xn,F,C,Xi | |||||||||
Risk Statements | 10-22-52/53 | |||||||||
Safety Statements | 61-16 | |||||||||
RIDADR | UN 3272 3/PG 3 | |||||||||
WGK Germany | 2 | |||||||||
Hazard Note | Flammable/Corrosive | |||||||||
TSCA | T | |||||||||
HazardClass | 3 | |||||||||
PackingGroup | III | |||||||||
HS Code | 29183000 | |||||||||
NFPA 704 |
|
Ethyl 4,4,4-trifluoroacetoacetate price More Price(36)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TCI Chemical | T0810 | Ethyl 4,4,4-Trifluoroacetoacetate >98.0%(GC) | 372-31-6 | 25g | $75 | 2024-03-01 | Buy |
TCI Chemical | T0810 | Ethyl 4,4,4-Trifluoroacetoacetate >98.0%(GC) | 372-31-6 | 100g | $195 | 2024-03-01 | Buy |
Alfa Aesar | A13717 | Ethyl trifluoroacetoacetate, 98+% | 372-31-6 | 10g | $39.65 | 2024-03-01 | Buy |
Alfa Aesar | A13717 | Ethyl trifluoroacetoacetate, 98+% | 372-31-6 | 50g | $128.65 | 2024-03-01 | Buy |
Sigma-Aldrich | E50205 | Ethyl 4,4,4-trifluoroacetoacetate 99% | 372-31-6 | 5g | $32.8 | 2024-03-01 | Buy |
Ethyl 4,4,4-trifluoroacetoacetate Chemical Properties,Uses,Production
Chemical Properties
Clear liquid
Uses
Ethyl 4,4,4-trifluoroacetoacetate is used in the synthesis of fluorinated 2-thiouracil analogs as antithyroid agents.
Uses
Widely used in the synthetic process of medicine, pesticides and organic intermediate.
Uses
Intermediate for agro chemicals and pharmaceuticals (mefloquine). Product Data Sheet
Flammability and Explosibility
Flammable
Synthesis
With an ethanol solution of sodium ethoxide as a catalyst and in the presence of an organic solvent, ethyl trifluoroacetate and ethyl acetate are subjected to a Claisen condensation reaction, and ethyl 4,4,4-trifluoroacetoacetate is synthesized.
Ethyl 4,4,4-trifluoroacetoacetate Preparation Products And Raw materials
Raw materials
Preparation Products
6-Fluoro-4-(trifluoromethyl)quinolin-2-amine ,97%
2-Hydroxy-4-(trifluoromethyl)quinoline
(5-(TRIFLUOROMETHYL)-1-METHYL-1H-PYRAZOL-4-YL)METHANAMINE
(1-TERT-BUTYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOL-4-YL)METHANOL
4-HYDROXY-2-(METHYLTHIO)-6-(TRIFLUOROMETHYL)PYRIMIDINE
7-HYDROXY-4-(TRIFLUOROMETHYL)COUMARIN
ethyl 2-(methylsulfanyl)-4-(trifluoromethyl)pyrimidine-5-carboxylate
1-METHYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOL-3-OL
4-BROMO-6-(TRIFLUOROMETHYL)PYRIMIDINE
(5-(TRIFLUOROMETHYL)-1-PHENYL-1H-PYRAZOL-4-YL)METHANOL
1-PHENYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID
5-(TRIFLUOROMETHYL)-1-METHYL-1H-PYRAZOLE-4-CARBONYL CHLORIDE
THIFLUZAMIDE
Ethyl 3-amino-4,4,4-trifluorocrotonate
4-BROMO-6-FLUORO-2-(TRIFLUOROMETHYL)QUINOLINE
ETHYL 1-(TERT-BUTYL)-5-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLATE
1-PHENYL-5-(TRIFLUOROMETHYL)PYRAZOLE-4-CARBONYL CHLORIDE
4-Methylpyrimidine
4-(Trifluoromethyl)quinoline-2-carbohydrazide ,97%
(6-Fluoro-4-(trifluoromethyl)quinolin-2-yl)methanol ,97%
Ethyl 6-fluoro-4-(trifluoromethyl)quinoline-2-carboxylate ,97%
Coumarin 151
ETHYL 2-PHENYL-3-(TRIFLUOROMETHYL)PYRAZOLE-4-CARBOXYLATE
(5-(TRIFLUOROMETHYL)-1-PHENYL-1H-PYRAZOL-4-YL)METHANAMINE
2-Bromo-6-fluoro-4-(trifluoromethyl)quinoline
6-FLUORO-4-HYDROXY-2-(TRIFLUOROMETHYL)QUINOLINE
(4-(Trifluoromethyl)quinolin-2-yl)methanol ,97%
ETHYL 3-(TRIFLUOROMETHYL)PYRAZOLE-4-CARBOXYLATE
4-(Trifluoromethyl)-2-(methylthio)pyrimidine-5-carboxylic acid ,97%
4-HYDROXY-2-(TRIFLUOROMETHYL)QUINOLINE
1of8
Global( 566)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43340 | 58 |
Nanjing Sinoda Biological Technology Co., Ltd | +8613401983379 | sales@njmcn.cn | CHINA | 74 | 58 |
Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8805 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-18789408387 | 1057@dideu.com | China | 3889 | 58 |
Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12830 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5889 | 58 |
Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29793 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18911 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21633 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | FandaChem@Gmail.com | China | 8754 | 55 |
View Lastest Price from Ethyl 4,4,4-trifluoroacetoacetate manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
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2025-02-05 | ethyl 4,4,4-trifluoroacetoacetate
372-31-6
|
US $0.00 / kg | 20kg | 99% | 20 tons | Qingdao RENAS Polymer Material Co., Ltd. | |
![]() |
2024-11-19 | Ethyl 4,4,4-trifluoroacetoacetate
372-31-6
|
US $10.00 / KG | 1KG | 99% | 10 mt | Hebei Weibang Biotechnology Co., Ltd | |
![]() |
2024-10-11 | Ethyl 4,4,4-trifluoroacetoacetate
372-31-6
|
US $9.10 / KG | 1KG | 99.% | 10000 | Hebei Chuanghai Biotechnology Co,.LTD |
-
- ethyl 4,4,4-trifluoroacetoacetate
372-31-6
- US $0.00 / kg
- 99%
- Qingdao RENAS Polymer Material Co., Ltd.
-
- Ethyl 4,4,4-trifluoroacetoacetate
372-31-6
- US $10.00 / KG
- 99%
- Hebei Weibang Biotechnology Co., Ltd
-
- Ethyl 4,4,4-trifluoroacetoacetate
372-31-6
- US $9.10 / KG
- 99.%
- Hebei Chuanghai Biotechnology Co,.LTD
372-31-6(Ethyl 4,4,4-trifluoroacetoacetate)Related Search:
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4,4,4-trifL
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Ethyl 4,4,4-trifluoroacetoa
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ETFAA
Ethyl-4,4,4-trifluoracetoacetat
4,4,4-Ethyl trifluoroacetyl acetate
Ethyl 4,4,4-trifluoroacetoacetate?New
372-31-6
373-31-6
371-31-6