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2-AMINO-3-(METHYLAMINO)PYRAZINE

2-AMINO-3-(METHYLAMINO)PYRAZINE Structure
2-AMINO-3-(METHYLAMINO)PYRAZINE structure
CAS No.
84996-40-7
Chemical Name:
2-AMINO-3-(METHYLAMINO)PYRAZINE
Synonyms
N-METHYLPYRAZINE-2,3-DIAMINE;N2-methylpyrazine-2,3-diamin;N2-methylpyrazine-2,3-diamine;2,3-Pyrazinediamine, N2-methyl-;2-AMINO-3-(METHYLAMINO)PYRAZINE
CBNumber:
CB1138793
Molecular Formula:
C5H8N4
Molecular Weight:
124.14
MDL Number:
MFCD08460070
MOL File:
84996-40-7.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:54
Product description Number Pack Size Price
2-Amino-3-(methylamino)pyrazine A578080 100mg $65
2-Amino-3-(methylamino)pyrazine FA154142 250mg $95
2-Amino-3-(methylamino)pyrazine FA154142 500mg $165
2-Amino-3-(methylamino)pyrazine 95+% 118862 250mg $180
N2-Methylpyrazine-2,3-diamine Y6424 1g $211
Request For Quotation

2-AMINO-3-(METHYLAMINO)PYRAZINE Properties

storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
Appearance Yellow to brown Solid

2-AMINO-3-(METHYLAMINO)PYRAZINE price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC A578080 2-Amino-3-(methylamino)pyrazine 84996-40-7 100mg $65 2021-12-16 Buy
Biosynth Carbosynth FA154142 2-Amino-3-(methylamino)pyrazine 84996-40-7 250mg $95 2021-12-16 Buy
Biosynth Carbosynth FA154142 2-Amino-3-(methylamino)pyrazine 84996-40-7 500mg $165 2021-12-16 Buy
Matrix Scientific 118862 2-Amino-3-(methylamino)pyrazine 95+% 84996-40-7 250mg $180 2021-12-16 Buy
AK Scientific Y6424 N2-Methylpyrazine-2,3-diamine 84996-40-7 1g $211 2021-12-16 Buy
Product number Packaging Price Buy
A578080 100mg $65 Buy
FA154142 250mg $95 Buy
FA154142 500mg $165 Buy
118862 250mg $180 Buy
Y6424 1g $211 Buy

2-AMINO-3-(METHYLAMINO)PYRAZINE Chemical Properties,Uses,Production

Synthesis

2-Amino-3-chloropyrazine

6863-73-6

Methylamine

74-89-5

2-AMINO-3-(METHYLAMINO)PYRAZINE

84996-40-7

General procedure for the synthesis of 2-amino-3-methylaminopyrazine from 2-amino-3-chloropyrazine (5.20 g, 40.1 mmol) and monomethylamine: 2-amino-3-chloropyrazine (5.20 g, 40.1 mmol) and CuSO4 (640 mg, 4.01 mmol) in 12 M aqueous methylamine solution (40.0 mL, 480 mmol) were The mixture was placed in a microwave reactor and the reaction was stirred at 120 °C for 3 hours. Upon completion of the reaction, the reaction mixture was cooled to room temperature and concentrated under reduced pressure to remove the solvent. The residue was purified by fast column chromatography (silica gel as stationary phase and chloroform solution with 0-5% methanol as eluent) to afford the target product 2-amino-3-methylaminopyrazine (3.99 g, 80% yield) as a yellow solid. The structure of the product was confirmed by 1H NMR (DMSO-d6) and mass spectrometry (ESI): 1H NMR (DMSO-d6) δ 2.81 (d, 3H, J=4.7 Hz), 5.84 (s, 2H), 6.13 (q, 1H, J=4.7 Hz), 7.09 (d, 1H, J=3.1 Hz), 7.23 (d, 1H, J=3.1 Hz ); MS (ESI) m/z 125 [M+H]+.

References

[1] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 13, p. 3515 - 3526

2-AMINO-3-(METHYLAMINO)PYRAZINE synthesis

6863-73-6
74-89-5
84996-40-7
Synthesis of 2-AMINO-3-(METHYLAMINO)PYRAZINE from 2-Amino-3-chloropyrazine and Methylamine

2-AMINO-3-(METHYLAMINO)PYRAZINE Preparation Products And Raw materials

Raw materials

2-Amino-3-chloropyrazine 2-Amino-3-bromopyrazine Methylamine Copper(II) sulfate

Preparation Products

2-AMINO-3-(METHYLAMINO)PYRAZINE Suppliers

Global( 47)Suppliers
Supplier Tel Email Country ProdList Advantage
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30229 58
Aladdin Scientific 		tp@aladdinsci.com United States 52923 58
DAYANG CHEM (HANGZHOU) CO.,LTD 		+86-88938639 +86-17705817739 info@dycnchem.com China 53899 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10186 62
Wuhan Greenkj Pharmaceutical Technology Co., Ltd. 15608630565 greenkjpharm@163.com China 130 58
Aikon International Limited 025-58859352 18068836627 sales01@aikonchem.com China 15083 58
Shanghai Jizhi Biochemical Technology Co. Ltd. 4009004166/18616739031 18616739031 3007523370@qq.com China 52687 58
Chengdu Feibai Pharmaceutical Co., Ltd. 028-84641798 18782128315 3302391190@qq.com China 9795 55
Supplier Advantage
Alchem Pharmtech,Inc. 		58
Career Henan Chemica Co 		58
Aladdin Scientific 		58
DAYANG CHEM (HANGZHOU) CO.,LTD 		58
Amadis Chemical Company Limited 		58
Pure Chemistry Scientific Inc. 62
Wuhan Greenkj Pharmaceutical Technology Co., Ltd. 58
Aikon International Limited 58
Shanghai Jizhi Biochemical Technology Co. Ltd. 58
Chengdu Feibai Pharmaceutical Co., Ltd. 55

2-AMINO-3-(METHYLAMINO)PYRAZINE Spectrum

2-AMINO-3-(METHYLAMINO)PYRAZINE(84996-40-7)1HNMR

84996-40-7(2-AMINO-3-(METHYLAMINO)PYRAZINE)Related Search:

Aminopyrazine TIMTEC-BB SBB006492 N-1,3-BENZODIOXOL-5-YL-6-(4-METHYLPIPERIDIN-1-YL)[1,2,5]OXADIAZOLO[3,4-B]PYRAZIN-5-AMINE 2-([6-(4-CHLOROANILINO)[1,2,5]OXADIAZOLO[3,4-B]PYRAZIN-5-YL]AMINO)-1-ETHANOL 4,11-DIHYDRO[1,2,5]OXADIAZOLO[3',4':5,6]PYRAZINO[2,3-B]QUINOXALINE
N-[6-(4-FLUOROANILINO)[1,2,5]OXADIAZOLO[3,4-B]PYRAZIN-5-YL]-N-(4-FLUOROPHENYL)AMINE ZERENEX E/6022362 N,N'-BIS(2-METHOXYPHENYL)QUINOXALINE-2,3-DIAMINE N-(BENZO[D][1,3]DIOXOL-5-YL)-6-(4-BENZYLPIPERIDIN-1-YL)-[1,2,5]OXADIAZOLO[3,4-B]PYRAZIN-5-AMINE AURORA 12630
N-[3-(4-fluoroanilino)-2-quinoxalinyl]-N-(4-fluorophenyl)amine N-(6-AMINO[1,2,5]OXADIAZOLO[3,4-B]PYRAZIN-5-YL)-N-(2-FLUOROPHENYL)AMINE N,N'-dimethylquinoxaline-2,3-diamine AURORA 12631 N-[6-(2-FLUOROANILINO)[1,2,5]OXADIAZOLO[3,4-B]PYRAZIN-5-YL]-N-(2-FLUOROPHENYL)AMINE
6,12-DIHYDRO[1,2,5]OXADIAZOLO[3',4':5,6]PYRAZINO[2,3-B][1,2,5]THIADIAZOLO[3,4-F]QUINOXALINE 2,3-DIANILINO-6-NITROQUINOXALINE AURORA 14733

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N-METHYLPYRAZINE-2,3-DIAMINE 2-AMINO-3-(METHYLAMINO)PYRAZINE N2-methylpyrazine-2,3-diamine 2,3-Pyrazinediamine, N2-methyl- N2-methylpyrazine-2,3-diamin 84996-40-7