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2-(2-CHLOROPHENYL)-2-HYDROXYETHYL CARBAMATE

CAS No.
194085-75-1
Chemical Name:
2-(2-CHLOROPHENYL)-2-HYDROXYETHYL CARBAMATE
Synonyms
YKP 509;RWJ 333369;Carisbamate;JNJ 10234094;(S)-Carisbamate;CarisbaMate (RWJ-333369);2-(2-CHLOROPHENYL)-2-HYDROXYETHYL CARBAMATE;[(2S)-2-(2-chlorophenyl)-2-hydroxyethyl] carbamate;1,2-ETHANEDIOL,1-(2-CHLOROPHENYL)-, 2-CARBAMATE, (S)-;1,2-Ethanediol,1-(2-chlorophenyl)-, 2-carbaMate, (1S)-
CBNumber:
CB11474577
Molecular Formula:
C813CH8D2Cl15NO3
Molecular Weight:
215.63
MDL Number:
MFCD15071195
MOL File:
194085-75-1.mol
MSDS File:
SDS
Last updated:2025-01-27 09:38:02

2-(2-CHLOROPHENYL)-2-HYDROXYETHYL CARBAMATE Properties

Melting point 131-132°C
storage temp. Refrigerator
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
color White to Off-White
optical activity [α]/D +77 to +87°, c =0.2 in chloroform-d
FDA UNII P7725I9V3Z
ATC code N03AX19
UNSPSC Code 12352200
NACRES NA.77

2-(2-CHLOROPHENYL)-2-HYDROXYETHYL CARBAMATE price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 23514 Carisbamate ≥98% 194085-75-1 500μg $121 2024-03-01 Buy
Cayman Chemical 23514 Carisbamate ≥98% 194085-75-1 1mg $218 2024-03-01 Buy
TRC C183510 (S)-Carisbamate 194085-75-1 5mg $215 2021-12-16 Buy
American Custom Chemicals Corporation API0009416 CARISBAMATE 95.00% 194085-75-1 1MG $315 2021-12-16 Buy
AK Scientific X3698 (S)-Carisbamate 194085-75-1 1mg $340 2021-12-16 Buy
Product number Packaging Price Buy
23514 500μg $121 Buy
23514 1mg $218 Buy
C183510 5mg $215 Buy
API0009416 1MG $315 Buy
X3698 1mg $340 Buy

2-(2-CHLOROPHENYL)-2-HYDROXYETHYL CARBAMATE Chemical Properties,Uses,Production

Description

Carisbamate is an antiepileptic agent., In vivo, administration of carisbamate (10-60 mg/kg) dose-dependently reduces spike and wave discharges in the frontoparietal cortex in a rat model of absence seizures. Carisbamate (10 mg/kg) increases latency to the first running episode in the Wistar audiogenic sensitive rat model of convulsive seizures. It also reduces motor seizure frequency in a rat model of spontaneous seizures in a dose-dependent manner. Carisbamate blocks Nav1.2 channels (IC50 = 68 μM for rat channels) and inhibits repetitive firing of action potentials in rat hippocampal neurons in a dose-dependent manner. It also reduces T-type Ca2+ currents in HEK cells transfected with human recombinant Cav3.1 channels at a concentration of 300 μM.

Uses

Carisbamate is being developed for adjuvant treatment of partial onset epilepsy. Carisbamate produces anticonvulsant effects in primary generalized, complex partial and absence-type seizure models, and exhibits neuroprotective and antiepileptogenic properties in rodent epilepsy models.

Uses

Labelled Carisbamate; it is being developed for adjuvant treatment of partial onset epilepsy. Carisbamate produces anticonvulsant effects in primary generalized, complex partial and absence-type seizu re models, and exhibits neuroprotective and antiepileptogenic properties in rodent epilepsy models.

Definition

ChEBI: Carisbamate is an organochlorine compound.

2-(2-CHLOROPHENYL)-2-HYDROXYETHYL CARBAMATE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 31)Suppliers
Supplier Tel Email Country ProdList Advantage
Jinan Carbotang Biotech Co.,Ltd.
+8615866703830 figo.gao@foxmail.com China 8497 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28172 58
AFINE CHEMICALS LIMITED
+86-0571-85134551 sales@afinechem.com China 15352 58
Nantong HI-FUTURE Biology Co., Ltd.
+undefined18051384581 sales@chemhifuture.com China 3135 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38631 58
GIHI CHEMICALS CO.,LIMITED
+8618058761490 info@gihichemicals.com China 49980 58
Zibo Hangyu Biotechnology Development Co., Ltd
+86-0533-2185556 +8617865335152 Mandy@hangyubiotech.com China 10986 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 57505 58
TargetMol Chemicals Inc.
+8613564774135 zijue.cai@tsbiochem.com United States 19881 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76

View Lastest Price from 2-(2-CHLOROPHENYL)-2-HYDROXYETHYL CARBAMATE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Carisbamate pictures 2024-10-28 Carisbamate
194085-75-1
US $1990.00-1190.00 / mg 10g TargetMol Chemicals Inc.
  • Carisbamate pictures
  • Carisbamate
    194085-75-1
  • US $1990.00-1190.00 / mg
  • TargetMol Chemicals Inc.
2-(2-CHLOROPHENYL)-2-HYDROXYETHYL CARBAMATE Carisbamate (S)-Carisbamate 1,2-Ethanediol,1-(2-chlorophenyl)-, 2-carbaMate, (1S)- JNJ 10234094 RWJ 333369 YKP 509 CarisbaMate (RWJ-333369) [(2S)-2-(2-chlorophenyl)-2-hydroxyethyl] carbamate 1,2-ETHANEDIOL,1-(2-CHLOROPHENYL)-, 2-CARBAMATE, (S)- 194085-75-1 C813CH8D2Cl15NO3 Amines Aromatics Chiral Reagents Intermediates & Fine Chemicals Isotope Labelled Compounds Pharmaceuticals