2-(2-CHLOROPHENYL)-2-HYDROXYETHYL CARBAMATE
- CAS No.
- 194085-75-1
- Chemical Name:
- 2-(2-CHLOROPHENYL)-2-HYDROXYETHYL CARBAMATE
- Synonyms
- YKP 509;RWJ 333369;Carisbamate;JNJ 10234094;(S)-Carisbamate;CarisbaMate (RWJ-333369);2-(2-CHLOROPHENYL)-2-HYDROXYETHYL CARBAMATE;[(2S)-2-(2-chlorophenyl)-2-hydroxyethyl] carbamate;1,2-ETHANEDIOL,1-(2-CHLOROPHENYL)-, 2-CARBAMATE, (S)-;1,2-Ethanediol,1-(2-chlorophenyl)-, 2-carbaMate, (1S)-
- CBNumber:
- CB11474577
- Molecular Formula:
- C813CH8D2Cl15NO3
- Molecular Weight:
- 215.63
- MDL Number:
- MFCD15071195
- MOL File:
- 194085-75-1.mol
- MSDS File:
- SDS
| Melting point | 131-132°C |
|---|---|
| storage temp. | Refrigerator |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| color | White to Off-White |
| FDA UNII | P7725I9V3Z |
| ATC code | N03AX19 |
2-(2-CHLOROPHENYL)-2-HYDROXYETHYL CARBAMATE price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 23514 | Carisbamate ≥98% | 194085-75-1 | 500μg | $121 | 2024-03-01 | Buy |
| Cayman Chemical | 23514 | Carisbamate ≥98% | 194085-75-1 | 1mg | $218 | 2024-03-01 | Buy |
| TRC | C183510 | (S)-Carisbamate | 194085-75-1 | 5mg | $215 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0009416 | CARISBAMATE 95.00% | 194085-75-1 | 1MG | $315 | 2021-12-16 | Buy |
| AK Scientific | X3698 | (S)-Carisbamate | 194085-75-1 | 1mg | $340 | 2021-12-16 | Buy |
2-(2-CHLOROPHENYL)-2-HYDROXYETHYL CARBAMATE Chemical Properties,Uses,Production
Description
Carisbamate is an antiepileptic agent., In vivo, administration of carisbamate (10-60 mg/kg) dose-dependently reduces spike and wave discharges in the frontoparietal cortex in a rat model of absence seizures. Carisbamate (10 mg/kg) increases latency to the first running episode in the Wistar audiogenic sensitive rat model of convulsive seizures. It also reduces motor seizure frequency in a rat model of spontaneous seizures in a dose-dependent manner. Carisbamate blocks Nav1.2 channels (IC50 = 68 μM for rat channels) and inhibits repetitive firing of action potentials in rat hippocampal neurons in a dose-dependent manner. It also reduces T-type Ca2+ currents in HEK cells transfected with human recombinant Cav3.1 channels at a concentration of 300 μM.
Uses
Labelled Carisbamate; it is being developed for adjuvant treatment of partial onset epilepsy. Carisbamate produces anticonvulsant effects in primary generalized, complex partial and absence-type seizu re models, and exhibits neuroprotective and antiepileptogenic properties in rodent epilepsy models.
Uses
Carisbamate is being developed for adjuvant treatment of partial onset epilepsy. Carisbamate produces anticonvulsant effects in primary generalized, complex partial and absence-type seizure models, an d exhibits neuroprotective and antiepileptogenic properties in rodent epilepsy models.
Uses
Carisbamate is being developed for adjuvant treatment of partial onset epilepsy. Carisbamate produces anticonvulsant effects in primary generalized, complex partial and absence-type seizure models, and exhibits neuroprotective and antiepileptogenic properties in rodent epilepsy models.
Definition
ChEBI: Carisbamate is an organochlorine compound.
2-(2-CHLOROPHENYL)-2-HYDROXYETHYL CARBAMATE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 6992 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| AFINE CHEMICALS LIMITED | 0571-85134551 | info@afinechem.com | CHINA | 15377 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3136 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49999 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 11013 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |