ChemicalBook >> CAS DataBase List >>N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenylpyrimidine-2,4-diamine
N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenylpyrimidine-2,4-diamine
![N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenylpyrimidine-2,4-diamine Structure](CAS/GIF/916603-07-1.gif)
- CAS No.
- 916603-07-1
- Chemical Name:
- N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenylpyrimidine-2,4-diamine
- Synonyms
- CZC-8004;CZC 00008004;DianilinopyriMidine_01;Dianilinopyrimidine_01(CZC8004);N-(4-broMophenyl)-N-(naphthalen-2-yl);N-(4-broMophenyl)-N-(naphthalen-2-yl) naphthalen-1-aMine;Target-5 (Kinase Probe Tool, APM-1)/Dianilinopyrimidine_01;N2-(4-(aminomethyl)phenyl)-5-fluoro-N4-phenylpyrimidine-2,4-...;N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenylpyrimidine-2,4-diamine;N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenyl-2,4-pyrimidinediamine
- CBNumber:
- CB11565156
- Molecular Formula:
- C17H16FN5
- Molecular Weight:
- 309.34
- MDL Number:
- MFCD16251195
- MOL File:
- 916603-07-1.mol
Last updated:2023-09-20 16:43:00
| Boiling point | 514.1±60.0 °C(Predicted) |
|---|---|
| Density | 1.332 |
| storage temp. | -20° |
| solubility | Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 2.5 mg/ml with warming) |
| pka | 9.14±0.10(Predicted) |
| form | solid |
| color | Off-white |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months. |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314-H290 | |||||||||
| Precautionary statements | P501-P260-P234-P264-P280-P390-P303+P361+P353-P301+P330+P331-P363-P304+P340+P310-P305+P351+P338+P310-P406-P405 | |||||||||
| NFPA 704 |
|
N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenylpyrimidine-2,4-diamine price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 16718 | CZC-8004 ≥98% | 916603-07-1 | 500μg | $81 | 2024-03-01 | Buy |
| Cayman Chemical | 16718 | CZC-8004 ≥98% | 916603-07-1 | 1mg | $143 | 2024-03-01 | Buy |
| Cayman Chemical | 16718 | CZC-8004 ≥98% | 916603-07-1 | 5mg | $396 | 2024-03-01 | Buy |
| Cayman Chemical | 16718 | CZC-8004 ≥98% | 916603-07-1 | 10mg | $632 | 2024-03-01 | Buy |
| TRC | A617370 | N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenylpyrimidine-2,4-diamine | 916603-07-1 | 10mg | $500 | 2021-12-16 | Buy |
N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenylpyrimidine-2,4-diamine Chemical Properties,Uses,Production
Description
CZC-8004 (916603-07-1) is a pan-specific kinase inhibitor. May be coupled to sepharose via its amino-side chain for affinity chromatography applications1.
Uses
A novel enzyme-interacting compounds using immobilized broad-spectrum ligands
Uses
CZC-8004 is an aminopyrimidine that binds a range of tyrosine kinases, including ABL, BTK, FAK, FER, JAK1, SRC, SYK, TEC, TNK1, TYK2, and YES. It inhibits these kinases at low micromolar concentrations and can be immobilized to capture and purify these enzymes.
Definition
ChEBI: CZC8004 is an aminopyrimidine and an organofluorine compound. It has a role as a protein kinase inhibitor.
References
1) Klutchko?et al. (1998),?2-Substituted aminopyrido[2,3-d]pyrilidin-7(8H)-ones, structure-activity relationships against selected tyrosine kinases and in vitro and in vivo anticancer activity; J. Med. Chem.,?41?3276
N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenylpyrimidine-2,4-diamine Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 66)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9923 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25363 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33349 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
View Lastest Price from N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenylpyrimidine-2,4-diamine manufacturers
916603-07-1(N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenylpyrimidine-2,4-diamine)Related Search:
DianilinopyriMidine_01
CZC 00008004
N-(4-broMophenyl)-N-(naphthalen-2-yl)
N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenyl-2,4-pyrimidinediamine
N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenylpyrimidine-2,4-diamine
N-(4-broMophenyl)-N-(naphthalen-2-yl) naphthalen-1-aMine
CZC-8004
Target-5 (Kinase Probe Tool, APM-1)/Dianilinopyrimidine_01
2,4-Pyrimidinediamine, N2-[4-(aminomethyl)phenyl]-5-fluoro-N4-phenyl-
N2-(4-(aminomethyl)phenyl)-5-fluoro-N4-phenylpyrimidine-2,4-...
CZC 8004,HER1,Vascular endothelial growth factor receptor,ErbB-1,Epidermal growth factor receptor,CZC-8004,CZC8004,aminopyrimidine,Inhibitor,tyrosine kinases,CZC 00008004,EGFR,CZC00008004,inhibit,VEGFR
Dianilinopyrimidine_01(CZC8004)
916603-07-1
C17H16FN5
Chemical Amines
Amines
Aromatics
Heterocycles