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Amitriptyline

Amitriptyline
Amitriptyline structure
CAS No.
50-48-6
Chemical Name:
Amitriptyline
Synonyms
n750;elani;mk230;N 750;Elanil;Elavil;Flavyl;MK-230;Larxyl;Adepril
CBNumber:
CB1159271
Molecular Formula:
C20H23N
Formula Weight:
277.4
MOL File:
50-48-6.mol

Amitriptyline Properties

Melting point:
196-197°C
Boiling point:
410.26°C (rough estimate)
Density 
0.9415 (rough estimate)
refractive index 
1.7500 (estimate)
pka
9.4(at 25℃)
Water Solubility 
9.7 mg/mL
CAS DataBase Reference
50-48-6(CAS DataBase Reference)
NIST Chemistry Reference
Amitriptyline(50-48-6)
EPA Substance Registry System
1-Propanamine, 3-(10,11-dihydro-5H-dibenzo[ a,d]cyclohepten-5-ylidene)- N,N-dimethyl-(50-48-6)
SAFETY
  • Risk and Safety Statements
HazardClass  IRRITANT

Amitriptyline Chemical Properties,Uses,Production

Uses

Antidepressant.

Definition

ChEBI: An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

brand name

Elavil (AstraZeneca); Endep (Roche);Ami-anelun;Amilent;Amilit-ifi;Aminiurin;Amitimid;Amitriptol;Amyline;Amyzol;Annolytin;Apo-amitriptylline;Apo-pram;Deprelio;Deprestal;Diapatal;Elatrolet;Elavil plus;Emitrip;Enovil;Entrafon-210;Entrafon-2-10;Entrafon-2-25;Entrafon-a;Entrafon-forte;Etarfon;Etrafon-a;Etrafon-forte;Laroxal;Larozyl;Levate;Limbatarail;Limbatral;Limbitryl;Limitrol;Longopax;Loxaryl;Mareline;Meravil;Muaban d;Mutaban a/d/f;Nobrital;Novotriptyn;Novotryptin;Novo-tryptin;Parks-plus;Pms levazine;Prouvil;Saratem;Sarotena;Sedans;Sylvemid;Tensorelax;Teperin;Trepiline;Trepulin;Triptizol;Triptonal;Triptpane;Trivial-4-10.

World Health Organization (WHO)

Amitriptyline, a tricyclic antidepressant was introduced in 1961 for the management of endogenous depression and is listed in the 8th WHO Model List of Essential Drugs. Much of the adverse effects are caused by its antimuscarinic actions. These include dry mouth, cardiac arrhythmias, central nervous system disturbances, blood disorders and risk of suicide. The risk of suicide and dangers related to overdosage led the Norwegian Medicines Control Authority to put the higher strength formulation under prescribing restriction in 1992. The risk of death following overdosage is apparently higher for products containing tricyclic compounds as compared with nontricyclic products.

Amitriptyline Preparation Products And Raw materials

Raw materials

Preparation Products


Amitriptyline Suppliers

Global( 52)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32447 55
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23976 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 sales@jushengtech.com CHINA 28236 58
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76
LGM Pharma 1-(800)-881-8210
615-250-9817 inquiries@lgmpharma.com United States 1940 70
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202,021-54308259
+86-21-64545202 info@hanhonggroup.com China 43260 64
Syntechem Co.,Ltd Please Email
E-Mail Inquiry info@syntechem.com China 13010 57
Jinan Haohua Industry Co., Ltd 0531-58773082 ;58773060
0531-58773099 sales@jnhaohua.com China 5585 58
BOC Sciences
info@bocsci.com United States 10507 65
Beijing HuaMeiHuLiBiological Chemical 010-56205725;010-86181995
010-65763397 waley188@sohu.com China 12341 58

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