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OROTIDINE

CAS No.
314-50-1
Chemical Name:
OROTIDINE
Synonyms
OROTIDINE;Orotidine ,98%;6-Carboxyuridine;URIDIN-6-CARBOXYLIC ACID;URIDINE-6-CARBOXYLIC ACID;orotidine free acid approx. 90%;Orotidine (Uridine-6-carboxylic acid);1,2,3,6-Tetrahydro-2,6-dioxo-3-β-D-ribofuranosyl-4-pyrimidinecarboxylic acid;4-Pyrimidinecarboxylicacid, 1,2,3,6-tetrahydro-2,6-dioxo-3-b-D-ribofuranosyl-;4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-3-β-D-ribofuranosyl-
CBNumber:
CB1164936
Molecular Formula:
C10H12N2O8
Molecular Weight:
288.21
MDL Number:
MFCD00057418
MOL File:
314-50-1.mol
Last updated:2023-05-18 11:31:01

OROTIDINE Properties

Melting point >400 °C
Density 1.847±0.06 g/cm3(Predicted)
storage temp. −20°C
solubility DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form Solid
pka 2.62±0.20(Predicted)
color White to Off-White
FDA UNII B350MC02GZ

SAFETY

Risk and Safety Statements

WGK Germany  3
HS Code  29349990

OROTIDINE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC O691520 Orotidine 314-50-1 1mg $95 2021-12-16 Buy
Usbiological 296366 Orotidine 314-50-1 1mg $531 2021-12-16 Buy
TRC O691520 Orotidine 314-50-1 25mg $1620 2021-12-16 Buy
Biosynth Carbosynth NO08048 Orotidine 314-50-1 25mg $1875 2021-12-16 Buy
Biosynth Carbosynth NO08048 Orotidine 314-50-1 0.0025g $90 2021-12-16 Buy
Product number Packaging Price Buy
O691520 1mg $95 Buy
296366 1mg $531 Buy
O691520 25mg $1620 Buy
NO08048 25mg $1875 Buy
NO08048 0.0025g $90 Buy

OROTIDINE Chemical Properties,Uses,Production

Uses

Orotidine is a metabolite of Orotic Acid (O691500); a compound used in the preparation of therapeutic agents for chronic obstructive pulmonary disease (COPD) treatment.

Definition

ChEBI: A nucleoside formed by attaching orotic acid to a ribose ring via a beta1N(1)-glycosidic bond.

Enzyme inhibitor

This water-soluble ribonucleoside (FWfree-acid = 288.21 g/mol; CAS 314-50- 1; lmax of 267 nm in 0.1 N HCl (e = 9570 cm–1M–1; another report lists 9800) and 265 nm in 0.1 N methanolic NaOH (e = 8960 cm–1M–1; another report lists 7800)), first observed in Neurospora crassa, is also foound in the urine of cancer patients treated with 6-azauridine, Orotidine is most likely formed from OMP, its 5’-monophosphate ester and the direct precursor of UMP. Orotidine is readily hydrolyzed in dilute mineral acids. Target(s): orotate phosphoribosyltransferase; orotidine-5’-phosphate decarboxylase.

OROTIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

OROTIDINE Suppliers

Global( 47)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21695 55
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
NewCan Biotech Limited
+86-0571-86912261 +8613735419629 sales@newcanbio.com China 10027 58
Henan Alfa Chemical Co., Ltd
+8618339805032 alfa4@alfachem.cn China 12755 58
ZHEJIANG JIUZHOU CHEM CO., LTD
+86-0576225566889 +86-13454675544 admin@jiuzhou-chem.com;jamie@jiuzhou-chem.com;alice@jiuzhou-chem.com China 20000 58
GIHI CHEMICALS CO.,LIMITED
+8618058761490 info@gihichemicals.com China 49999 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 57511 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131981 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Nanjing Chemlin Chemical Co., Ltd 025-83697070 info@chemlin.com.cn China 17939 64
OROTIDINE URIDINE-6-CARBOXYLIC ACID URIDIN-6-CARBOXYLIC ACID Orotidine (Uridine-6-carboxylic acid) 1,2,3,6-Tetrahydro-2,6-dioxo-3-β-D-ribofuranosyl-4-pyrimidinecarboxylic acid 6-Carboxyuridine 3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl]-2,6-diketo-pyrimidine-4-carboxylic acid Orotidine ,98% orotidine free acid approx. 90% 3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,6-dioxopyrimidine-4-carboxylic acid 4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-3-β-D-ribofuranosyl- 4-Pyrimidinecarboxylicacid, 1,2,3,6-tetrahydro-2,6-dioxo-3-b-D-ribofuranosyl- 3-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid 314-50-1 C10H13N2O11P C10H12N2O8 Biochemicals and Reagents BioChemical Nucleosides, Nucleotides, Oligonucleotides Nucleoside Analogs