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N-Acetyl-L-phenylalanine

N-Acetyl-L-phenylalanine structure

CAS No.: 2018-61-3

Chemical Name:: N-Acetyl-L-phenylalanine

Synonyms: AC-PHE-OH;Ac-L-Phe-OH;Acetylphenylalanine;L-Phenylalanine, N-acetyl-;N-Ac-L-Phe-OH;Ac-L-Phe;NSC 45699;ACETYL-L-PHENYLALANINE;(2S)-2-Acetamido-3-phenylpropanoic acid;H-Ac-Phe-OH

CBNumber:: CB1170986

Molecular Formula:: C11H13NO3

Molecular Weight:: 207.23

MDL Number:: MFCD00063158

MOL File:: 2018-61-3.mol

MSDS File:: SDS

Last updated:2023-06-26 08:28:19

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N-Acetyl-L-phenylalanine Properties

Melting point	171-173 °C(lit.)
alpha	40 º (c=1,methanol)
Boiling point	346.25°C (rough estimate)
Density	1.1878 (rough estimate)
refractive index	40 ° (C=5, MeOH)
storage temp.	Sealed in dry,Room Temperature
solubility	Solubility in methanol (almost transparency). Soluble in acetone and ethanol (20 mg/ ml).
form	Fine Crystalline Powder or Needles
pka	3.56±0.10(Predicted)
color	White to off-white
optical activity	[α]22/D +40.0°, c = 1 in methanol
InChIKey	CBQJSKKFNMDLON-JTQLQIEISA-N
CAS DataBase Reference	2018-61-3(CAS DataBase Reference)
FDA UNII	NP5BT39467
NIST Chemistry Reference	L-phenylalanine, n-acetyl-(2018-61-3)
EPA Substance Registry System	L-Phenylalanine, N-acetyl- (2018-61-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P305+P351+P338

Safety Statements

24/25

WGK Germany

TSCA

Yes

HS Code

29242990

NFPA 704

	1
0		0

N-Acetyl-L-phenylalanine price More Price(35)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	857459	N-Acetyl-L-phenylalanine ReagentPlus , 99%	2018-61-3	1g	$15	2024-03-01	Buy
Sigma-Aldrich	857459	N-Acetyl-L-phenylalanine ReagentPlus , 99%	2018-61-3	5g	$78.4	2024-03-01	Buy
TCI Chemical	A1541	N-Acetyl-L-phenylalanine >99.0%(T)	2018-61-3	5g	$18	2024-03-01	Buy
TCI Chemical	A1541	N-Acetyl-L-phenylalanine >99.0%(T)	2018-61-3	25g	$51	2024-03-01	Buy
Alfa Aesar	B23812	N-Acetyl-L-phenylalanine, 99%	2018-61-3	1g	$30.65	2024-03-01	Buy

Product number	Packaging	Price	Buy
857459	1g	$15	Buy
857459	5g	$78.4	Buy
A1541	5g	$18	Buy
A1541	25g	$51	Buy
B23812	1g	$30.65	Buy

N-Acetyl-L-phenylalanine Chemical Properties,Uses,Production

Chemical Properties

white to off-white fine cryst. powder or needles

Uses

N-Acetyl-L-phenylalanine is an protected analogue of L-Phenylalanine (P319415), an essential amino acid produced for medical, feed, and nutritional applications such as in the preparation of Aspartame.

Uses

It is an essential amino acid produced for medical, feed, and nutritional applications such as in the preparation of aspartame. It is applied as an antidepressant.

Definition

ChEBI: The N-acetyl derivative of L-phenylalanine.

General Description

N-Acetyl-L-phenylalanine is an acetyl analog of L-phenylalanine. It is widely used as a reactant to synthesize methyl or ethyl esters of N-acetyl-L-phenylalanine, which are employed as versatile building blocks in peptide synthesis.

Purification Methods

N-Acetyl-L-phenylalanine is recrystallised from H2O, 20% MeOH/H2O, or CHCl3; dry and store it at 4o. The (DL)-isomer crystallises from H2O, Me2CO, EtOAc, or CHCl3 with m 152-154o and the solubilities in w% at 25o are 0.73 (H2O), 4.3 (Me2CO), 0.79 (EtOAc) and 0.34 (CHCl3) [Kerr & Niemann J Org Chem 23 893 1958, Overby & Ingersoll J Am Chem Soc 73 3363 1951, L: Fu et al. J Am Chem Soc 76 6057 1954, Bender & Glasson J Am Chem Soc 81 1591 1959]. [Beilstein 14 I 238, 4 IV 1575.]

N-Acetyl-L-phenylalanine synthesis

Synthesis of N-Acetyl-L-phenylalanine from 2-Propenoic acid, 2-(acetylamino)-3-phenyl-, methyl ester

N-Acetyl-L-phenylalanine Preparation Products And Raw materials

Raw materials

Preparation Products

N-Acetyl-L-phenylalanine Suppliers

Global( 437)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15371	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21695	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
NINGBO INNO PHARMCHEM CO., LTD.	13867897135	sales@nbinno.com	CHINA	925	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Jinan Finer Chemical Co., Ltd	+86-531-88989536 +86-15508631887	sales@finerchem.com	China	2966	58
Accela ChemBio Inc.	(+1)-858-699-3322	info@accelachem.com	United States	19965	58
Huaian yishu technology co.,ltd	86-0517-85883738 13852390259	sales@yishuchem.com	CHINA	53	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
NINGBO INNO PHARMCHEM CO., LTD.	58
Hubei Jusheng Technology Co.,Ltd.	58
Jinan Finer Chemical Co., Ltd	58
Accela ChemBio Inc.	58
Huaian yishu technology co.,ltd	58

View Lastest Price from N-Acetyl-L-phenylalanine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2021-09-29	N-Acetyl-L-phenylalanine 2018-61-3	US $0.00 / Kg/Drum	1KG	98%min	500kgs	WUHAN FORTUNA CHEMICAL CO., LTD
2021-08-12	N-Acetyl-L-phenylalanine 2018-61-3	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd
2021-07-13	N-Acetyl-L-phenylalanine 2018-61-3	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd

N-Acetyl-L-phenylalanine
2018-61-3
US $0.00 / Kg/Drum
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

N-Acetyl-L-phenylalanine
2018-61-3
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

N-Acetyl-L-phenylalanine
2018-61-3
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

N-Acetyl-L-phenylalanine Spectrum

N-Acetyl-L-phenylalanine(2018-61-3)MS N-Acetyl-L-phenylalanine(2018-61-3)IR1 N-Acetyl-L-phenylalanine(2018-61-3)IR2 N-Acetyl-L-phenylalanine(2018-61-3)Raman

2018-61-3(N-Acetyl-L-phenylalanine)Related Search:

Folic acid Citric acid D-Phenylalanine N-(tert-Butoxycarbonyl)-L-phenylalanine Acetylacetone

DL-Phenylalanine Phenprobamate Acetyl coenzyme A sodium salt Ethyl 2-(Chlorosulfonyl)acetate L-Phenylalanine

Ascoric Acid Melphalan N-Acetyl-3,5-diiodo-L-tyrosine CHLOROACETYL-L-TYROSINE Aspartame

N-Glycyl-L-tyrosine Ethyl N-acetyl-L-tyrosinate hydrate N-CBZ-VAL-TYR METHYL ESTER

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(2S)-2-(Acetylamino)-3-phenylpropanoic acid (2S)-2-(Acetylamino)-3-phenylpropionic acid (S)-α-(Acetylamino)benzenepropanoic acid (αS)-α-(Acetylamino)benzenepropanoic acid N-Ac-Phenylalanine L-2-(ACETYLAMINO)-3-PHENYLPROPANOIC ACID AC-PHENYLALANINE N-acetyl-3-phenyl-L-alanine N-Acetyl-L-plhenylalanine N-ACETYL-L-PHENYLALANINE SIGMA GRADE N-Acetyl-L-phenylalanine, 99+% (2S)-acetylamino-3-phenyl-propanoic acid N-ACETYL-L-PHENYLALANINE:AC-PHE-OH N-alpha-Actetyl-L-phenylalanine N-ACETYL-L-PHENYLALANINE (2S)-N-ACETYL-L-PHENYLALANINE H-Ac-Phe-OH N-propionyl leucine (S)-2-AcetaMido-3-phenylpropanoic acid N-Acetyl-L-phenylalanine ReagentPlus(R), 99% Ac-Phe-OH ( N-acetyl-L-phenylalanine ) N-Acetyl-L-phenylalanine Vetec(TM) reagent grade, 98% (S)-2-(N-phenylacetamido)propanoic acid Acetyl-L-phenylalanine≥ 99% (HPLC) N-ALPHA-ACETYL-L-PHENYLALANINE Alanine, N-acetyl-3-phenyl-, L- L-N-Acetylphenylalanine N-Acetyl-l-phenalanine n-acetyl-l-phenylalanin Amino Acid Impurity 45 (2S)-2-acetamido-3-phenylpropanoate N-Acetyl-L-phenylalanine > N-Acetyl-L-phenylalanine USP/EP/BP N-acetyl-laevo-phenyl alanine (2S)-2-Acetamido-3-phenylpropanoic acid AC-PHE-OH ACETYL-L-PHENYLALANINE Ac-L-Phe-OH NSC 45699 Acetylphenylalanine L-Phenylalanine, N-acetyl- N-Ac-L-Phe-OH Ac-L-Phe 2018-61-3 C6H5CH2CHNHCOCH3CO2H Amino Acid Derivatives Peptide Synthesis Phenylalanine Specialty Synthesis chiral Amino Acids Derivatives Amino Acid Derivatives Amino Acids N-Acetyl-Amino acid series Amino Acid Derivatives Peptide Synthesis Phenylalanine Phenylalanine [Phe, F]