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D-Mannose

Description References
D-Mannose
D-Mannose structure
CAS No.
3458-28-4
Chemical Name:
D-Mannose
Synonyms
D-MAN;D-MANOSE;d-mannos;SEMINOSE;CB1175305;D-MANNOSE;NSC 26247;Aldohexos;CARUBINOSE;D-MannMtol
CBNumber:
CB1175305
Molecular Formula:
C6H12O6
Formula Weight:
180.16
MOL File:
3458-28-4.mol

D-Mannose Properties

Melting point:
133-140 °C(lit.)
alpha 
14 º (589nm, c=10, H2O)
Boiling point:
232.96°C (rough estimate)
Density 
1,539 g/cm3
refractive index 
1.5730 (estimate)
storage temp. 
Store at RT.
solubility 
H2O: 50 mg/mL
form 
powder
pka
12.08(at 25℃)
color 
White
optical activity
[α]20/D +13.8±0.5°, 24 hr, c = 10% in H2O
Water Solubility 
2480 g/L (17 ºC)
λmax
λ: 260 nm Amax: 0.1
λ: 280 nm Amax: 0.1
Sensitive 
Hygroscopic
Merck 
14,5747
BRN 
1564373
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKey
WQZGKKKJIJFFOK-ATJJXCEKSA-N
CAS DataBase Reference
3458-28-4(CAS DataBase Reference)
NIST Chemistry Reference
D-Mannose(3458-28-4)
EPA Substance Registry System
D-Mannose(3458-28-4)

SAFETY

Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  24/25-36-26
WGK Germany  3
3
TSCA  Yes
HS Code  29400010

D-Mannose price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 63579 D-(+)-Mannose BioUltra, ≥99.5% (sum of enantiomers, HPLC) 3458-28-4 10g $134 2018-11-20 Buy
Sigma-Aldrich 63580 D-(+)-Mannose for microbiology, ≥99% 3458-28-4 25g $50.8 2018-11-20 Buy
Alfa Aesar A10842 D-(+)-Mannose, 99% 3458-28-4 100g $84.8 2018-11-15 Buy
Alfa Aesar A10842 D-(+)-Mannose, 99% 3458-28-4 25g $33.1 2018-11-15 Buy
Sigma-Aldrich M8574 D-(+)-Mannose synthetic, ≥99% 3458-28-4 25g $36.8 2018-11-20 Buy

D-Mannose Chemical Properties,Uses,Production

Description

D-Mannose is a nutritional supplement that can be found in cranberries, peaches, apples, other berries, and some plants. D-mannose is a sugar that has an important role in human metabolism, especially in the glycosylation of certain proteins. D-mannose functionalizes by the inhibition of bacterial adherence to uroepithelial cells.
More than 90 percent of recurrent urinary tract infections (UTIs) are caused by Escherichia coli (E. coli), which is normally found in the intestinal tract. The cell walls of each E. coli are covered with tiny fingerlike projections called fimbria. Mannose can bind to the lectin on the bacteria’s fimbria so that the bacteria can be effectively rinsed out by urination.
D-Mannose is by far the most effective supplement for both treatment and prevention of UTIs. And it is used for the treating carbohydrate-deficient glycoprotein syndrome, an inherited metabolic disorder.

References

[1] http://www.webmd.com
[2] Bojana Kranjcˇec, Dino Papesˇ , Silvio Altarac (2013) D-mannose powder for prophylaxis of recurrent urinary tract infections in women: a randomized clinical trial, World J Urol, 32, 79-84

Chemical Properties

White crystalline powder

Uses

D-Mannose is a carbohydrate that is important in the glycosylation of molecules in a variety of cellular processes. It is involved in N and O glycosylation of bovine why protein products, used in inf ant formulas. It is also responsible for the O-glycosylation of the T helper cell-derived cytokine interlukin-17A, an important cell-signaling molecule.

Uses

It has been used in a study to assess the synthesis of a family of amphiphilic glycopolymers. It has also been used in a study to investigate the early detection of bronchiolitis obliterans after lung transplantation.

Definition

ChEBI: D-Mannopyranose having alpha-configuration at the anomeric centre.

Purification Methods

Crystallise -D(+)-mannose repeatedly from EtOH, aqueous 80% EtOH, AcOH or MeOH/propan-2-ol and then dry it in vacuo over P2O5 at 60o. [For 1H NMR and equilibr

D-Mannose Preparation Products And Raw materials

Raw materials

Preparation Products


D-Mannose Suppliers

Global( 351)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3203 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21954 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20680 55
Shanghai Time Chemicals CO., Ltd.
+86-021-57951555
+86-021-57951555 jack.li@time-chemicals.com CHINA 1367 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32457 55
Shanghai Yingrui Biopharma Co., Ltd.
+86-21-33585366 E-mail:sales03@shyrchem.com
+86-21-34979012 sales03@shyrchem.com CHINA 661 60
Xiamen AmoyChem Co., Ltd
+86 (0)592-605 1114
sales@amoychem.com CHINA 6374 58
GIHI CHEMICALS CO.,LIMITED
08657186217390
sales@gihichemicals.com CHINA 303 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 24001 58
Accela ChemBio Inc.
(+1)-858-699-3322
(+1)-858-876-1948 info@accelachem.com United States 12233 58

View Lastest Price from D-Mannose manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-08-02 D-Mannose
3458-28-4
US $30.00 / KG 10KG 99% 100kg career henan chemical co
2019-05-08 D-Mannose
3458-28-4
US $1.00 / KG 1KG 99% 200tons hdzhl biotechnology co., ltd
2019-04-11 d mannose E:candyli(at)speedgainpharma(dot)com
3458-28-4
US $10.00 / kg 1kg 99.5% 5000KG/WEEK Hebei Chisure Biotechnology Co., Ltd.

D-Mannose Spectrum


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