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LATHOSTEROL

CAS No.
80-99-9
Chemical Name:
LATHOSTEROL
Synonyms
LATHOSTEROL;γ-Cholestenol;GAMMA-CHOLESTENOL;Cholest-7-en-3-ol;gamma-cholesterol;DELTA7-Cholestenol;7-En-3-cholestanol;5Α-CHOLEST-7-EN-3-OL;7-Cholesten-3-beta-ol;5A-cholest-7-en-3B-ol
CBNumber:
CB1197244
Molecular Formula:
C27H46O
Molecular Weight:
386.65
MDL Number:
MFCD00056176
MOL File:
80-99-9.mol
Last updated:2023-05-18 11:31:11

LATHOSTEROL Properties

Melting point 126°C
Boiling point 452.8°C (rough estimate)
Density 0.9610 (rough estimate)
refractive index 1.5250 (estimate)
storage temp. -20°C
solubility Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Sonicated)
form Solid
pka 15.10±0.70(Predicted)
color White to Off-White

SAFETY

Risk and Safety Statements

WGK Germany  3
RTECS  FZ7000000

LATHOSTEROL price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C3652 5α-Cholest-7-en-3β-ol 80-99-9 25mg $111 2024-03-01 Buy
Sigma-Aldrich C3652 5α-Cholest-7-en-3β-ol 80-99-9 100mg $352 2024-03-01 Buy
Cayman Chemical 9003102 Lathosterol ≥98% 80-99-9 10mg $32 2024-03-01 Buy
Cayman Chemical 9003102 Lathosterol ≥98% 80-99-9 25mg $73 2024-03-01 Buy
Cayman Chemical 9003102 Lathosterol ≥98% 80-99-9 50mg $139 2024-03-01 Buy
Product number Packaging Price Buy
C3652 25mg $111 Buy
C3652 100mg $352 Buy
9003102 10mg $32 Buy
9003102 25mg $73 Buy
9003102 50mg $139 Buy

LATHOSTEROL Chemical Properties,Uses,Production

Uses

A Cholesterol (C432501) metabolite. Lathosterol (indicating cholesterol synthesis) and Sitosterol (indicating cholesterol absorption) also decreased with deteriorating health. Low Lathosterol, Sitosterol (S497050), and Cholesterol (C432501) predicted mortality additively and independently of each other.

Uses

5α-Cholest-7-en-3β-ol was used as a substrate in enzymatic assay for plasma cholesterol. It was used to supplement diet of Daphnia galeata to study the effect on life-history traits.

Uses

Lathosterol has been used as a standard for the estimation of the concentrations of cholesterol and plant sterols.

Definition

ChEBI: A cholestanoid that is (5alpha)-cholest-7-ene substituted by a beta-hydroxy group at position 3.

General Description

Lathosterol is a cholesterol synthesis precursor.

Biochem/physiol Actions

5α-Cholest-7-en-3β-ol (Lathosterol) is an intermediate in cholesterol biosynthesis pathway. Lathosterol in serum is carried on lipoproteins and is indicative of the rate of cholesterol synthesis. It acts as a marker of synthesis of cholesterol and is not affected by dietary consumption of cholesterol.

57-88-5
80-99-9
Synthesis of LATHOSTEROL from Cholesterol
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3BETA-HYDROXY-5ALPHA,7-CHOLESTENE 5ALPHA-CHOLEST-7-EN-3BETA-OL 7,(5-ALPHA)-CHOLESTEN-3-BETA-OL LATHOSTEROL GAMMA-CHOLESTENOL (3-beta,5-alpha)-cholest-7-en-3-o 3beta-Hydroxy-5alpha-cholest-7-ene 7-Cholesten-3-beta-ol Cholest-7-en-3-ol Cholest-7-en-3-ol, (3beta,5alpha)- delta(Sup7)-Cholestenol DELTA7-Cholestenol gamma-cholesterol 5A-cholest-7-en-3B-ol 3β-hydroxy-5α,7-cholestene 10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,5,6,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol 3β-Hydroxy-5α,7-cholestene, Lathosterol (3β,5α)-Cholest-7-en-3-ol 3β-Hydroxy-5α-cholest-7-ene 7-En-3-cholestanol γ-Cholestenol 5Α-CHOLEST-7-EN-3-OL;LATHOSTEROL 5α-cholest-7-en-3β-ol Cholest-7-en-3-ol, (3b,5a)- (3S,5S,9R,10S,13R,14R,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,5,6,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol Cholest-7-en-3-ol, (3β,5α)- 5α-c h ole st-7-e n-3β-ol (la th oste rol) Inhibitor,Endogenous Metabolite,Lathosterol,inhibit Cholesterol Impurity 16 (Lathosterol) (3S,5S,9R,10S,13R,14R,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol, 7, (5α)-CHOLESTEN-3β-OL 5Α-CHOLEST-7-EN-3-OL 80-99-9 Biochemicals and Reagents BioChemical Cholesterol and Derivatives Lipids Sterols Intermediates & Fine Chemicals Pharmaceuticals Steroids