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Benzocaine

Indications and Usage

CAS No. 94-09-7
Chemical Name: Benzocaine
Synonyms: Solu H;Norcain;Ora-jel;ORTHESIN;Ethoform;Norcaine;Topcaine;Euphagin;NSC 4688;AETHOFORM
CBNumber: CB1217951
Molecular Formula: C9H11NO2
Formula Weight: 165.19
MOL File: 94-09-7.mol
Benzocaine Property
Melting point : 88-90 °C
Boiling point : 172 °C (12.7517 mmHg)
density : 1.17
Fp : 172°C/13mm
storage temp. : 0-6°C
solubility : alcohol: soluble1 gm in 5 ml
form : Crystalline Powder
pka: 2.5(at 25℃)
color : White
Water Solubility : Soluble in ethanol, chloroform, ethyl ether and dilute acids. Sparingly soluble in water
Merck : 14,1086
BRN : 638434
Stability:: Stable. Combustible. Incompatible with strong oxidizing agents.
CAS DataBase Reference: 94-09-7(CAS DataBase Reference)
NIST Chemistry Reference: Benzoic acid, 4-amino-, ethyl ester(94-09-7)
EPA Substance Registry System: Benzoic acid, 4-amino-, ethyl ester(94-09-7)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes : Xi,T,F
Risk Statements : 43-36/37/38-39/23/24/25-23/24/25-11
Safety Statements : 22-24/25-37/39-26-24-45-36/37-16-7
RIDADR : 3077
WGK Germany : 2
RTECS : DG2450000
TSCA : Yes
PackingGroup : III
HS Code : 29224995
Hazardous Substances Data: 94-09-7(Hazardous Substances Data)
Symbol(GHS):
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger P260, P264, P270, P307+P311, P321,P405, P501
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger P260, P264, P270, P314, P501
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P272 Contaminated work clothing should not be allowed out of the workplace.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P321 Specific treatment (see … on this label).
P391 Collect spillage. Hazardous to the aquatic environment
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P307+P311 IF exposed: call a POISON CENTER or doctor/physician.
P333+P313 IF SKIN irritation or rash occurs: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Benzocaine Chemical Properties,Usage,Production

Indications and Usage
Benzocaine is a colorless trapezial crystal. Its melting point is 92℃ (88-90℃), boiling point is 183-184°C (1.87kPa). 1g of this drug is soluble in about 2500ml water, 5ml ethanol, 2ml chloroform, 4ml ether or 30-50ml almond oil and olive oil, and it is also soluble in dilute acid. It is stable in air, odorless, and slightly bitter.
Benzocaine is a lipid-soluble surface anesthetic, and it weaker than other local anesthetics such as lidocaine and tetracaine, so it will not cause any discomfort due to its anesthetizing effects when acting on mucosa. Benzocaine is a type of drug with relatively strong lipid-solubility and will bind with mucosa and the fatty layer of skin, but it will not easily penetrate into the body and cause poisoning. Benzocaine can be used as a precursor for Ossur imitation, orthocaine, and procaine. It is also used as a local anesthetic and can stop pain and itching. It is mainly used in pain and itch prevention on wounds, ulcer surfaces, mucous membrane surfaces and hemorrhoids. Its paste form can also lubricate and stop pain for the nasopharynx and endoscope. Benzocaine’s aural solution is used to alleviate acute congestion, concentrated otitis externa, and the pain and itching of swimming otitis. Benzocaine is also effective for toothaches, sore throat, oral ulcers, all kinds of hemorrhoids, anal fissures, and vulvar itching. Benzocaine can be used as a male sex organ numbing agent to slow ejaculation. It can also be used as a numbing lubricant for the pharynx and endoscope, and it can be used as a UV absorbing agent for cosmetics.
Chemical Properties
white odourless crystals
Uses
A commonly used topical pain reliever. Main active ingredient in anesthetic ointments.
Uses
Anesthetic;Na+ channel blocker
Uses
Benzocaine is used as an anesthetic (local).
Benzocaine Preparation Products And Raw materials
Raw materials
4-Aminobenzoic acid Ethyl p-nitrobenzoate 4-Aminophthalic acid
Preparation Products
Benzonatate 4-Fluorobenzoic acid Ethyl 4-(butylamino)benzoate
Benzocaine Suppliers      Global( 351)Suppliers     
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd. 0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3230 55
Innovation Medicine Technology Co.,LTD +86-0311-80690116 15716910116
+86-0311-80690116 sales@innovation-api.com CHINA 95 50
Changzhou Sunlight Pharmaceutical Co., Ltd +86-519-83131668 ; 83137042;83139028;83138042
+86-519-83138041 info@sunlightchem.com China 99 69
Chengdu XiYa Chemical Technology Co., Ltd. 4008-626-111
028-84752058 sale@xiyashiji.com China 9747 57
Shanghai Everchem Co., Ltd 86-29-81325371
+86-29-81325373 info@everchem.cn China 88 62
Changzhou Sunchem Pharmaceutical Chemical Material Co.,Ltd. 0519-85269522;13660798926
013660798926 850311@sunkechem.com China 100 60
iFar Chemical Technology +86-510-83488850;66896080
+86-510-83706633 sales@ifar.com.cn China 74 50
Changzhou Sunlight Farmacéutica.S.L. 0519-83138357,13706121722
0519-83138041 810308@sunlightchem.com China 51 60
Changzhou Yonghe Fine Chemical Co., Ltd. 0519-88552298;13921086978
86-519-88552298 xuxiaosong1972@163.com China 47 65
WuHan YuanCheng Gongchuang Technology Co.Ltd 027-88211053/88218372 QQ2355880512
027-88608190-969 gy08@yccreate.com China 3088 55
 
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