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Sasapyrine

Sasapyrine
Sasapyrine
CAS No.
552-94-3
Chemical Name:
Sasapyrine
Synonyms
diagen;Salina;salflex;Salysal;Disalyl;Nobacid;Salical;salgesic;salsitab;Arcylate
CBNumber:
CB1240724
Molecular Formula:
C14H10O5
Formula Weight:
258.23
MOL File:
552-94-3.mol

Sasapyrine Properties

Melting point:
139-151 °C
Boiling point:
361.48°C (rough estimate)
Density 
1.3326 (rough estimate)
refractive index 
1.4825 (estimate)
storage temp. 
room temp
solubility 
DMSO: ≥15mg/mL
pka
pKa 3.5 (Uncertain);9.8 (Uncertain)
form 
Crystalline Powder
color 
white to tan
Water Solubility 
HYDROLYSIS
Sensitive 
Moisture Sensitive
Merck 
14,8339
CAS DataBase Reference
552-94-3
NIST Chemistry Reference
2-Carboxyphenyl salicylate(552-94-3)
EPA Substance Registry System
Benzoic acid, 2-hydroxy-, 2-carboxyphenyl ester(552-94-3)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xi,N,Xn
Risk Statements  36/37/38-50-22
Safety Statements  37/39-26-61
RIDADR  UN 3077 9 / PGIII
WGK Germany  3
RTECS  DH2080000
TSCA  Yes
HS Code  29182300
Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
H400 Very toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 1 Warning P273, P391, P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P273 Avoid release to the environment.
P391 Collect spillage. Hazardous to the aquatic environment
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Sasapyrine price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR1941 Salsalate (Aspirin Impurity E) Pharmaceutical Secondary Standard; Certified Reference Material 552-94-3 200mg $219 2018-11-13 Buy
Sigma-Aldrich 1609807 Salsalate United States Pharmacopeia (USP) Reference Standard 552-94-3 150mg $352.8 2018-11-13 Buy
TCI Chemical S0129 2-Carboxyphenyl Salicylate >98.0%(HPLC)(T) 552-94-3 25g $34 2018-11-22 Buy
TCI Chemical S0129 2-Carboxyphenyl Salicylate >98.0%(HPLC)(T) 552-94-3 100g $74 2018-11-22 Buy
Alfa Aesar B22444 Salicylsalicylic acid, 98% 552-94-3 100g $142 2018-11-13 Buy

Sasapyrine Chemical Properties,Uses,Production

Chemical Properties

white crystalline powder

Uses

Nonacetylated aspirin analog. Analgesic, anti-inflammatory.

Definition

ChEBI: A dimeric benzoate ester obtained by intermolecular condensation between the carboxy of one molecule of salicylic acid with the phenol group of a second. It is a prodrug for salycylic acid that is used for treatment of rheumatoid arthritis and osteoarthrit s and also shows activity against type II diabetes.

Uses

Nonacetylated (e.g., sodium salicylate) and acetylated (aspirin) forms of salicylate are widely used to target inflammation in the treatment of insulin resistance, type 2 diabetes, or rheumatic pain. Salsalate is a dimeric prodrug comprising two esterified salicylate moieties. It is advantageous over sodium salicylate because it is insoluble at the acid pH of the stomach and passes suspended but undissolved into the small intestine, sparing the gastric mucosa direct contact. Proof-of-principle clinical studies demonstrate that 3-4.5 g/d salsalate can reduce blood glucose, triglyceride, free fatty acid and C-reactive protein concentrations, improve glucose utilization, and increase circulating insulin and adiponectin concentrations in obese adults at risk for the development of type 2 diabetes as well as for patients with type 2 diabetes.

brand name

Disalcid (3M Pharmaceuticals).

Sasapyrine Preparation Products And Raw materials

Raw materials

Preparation Products


Sasapyrine Suppliers

Global( 134)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 sales@capotchem.com China 19958 60
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32764 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 20001 58
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)
+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing) sh@meryer.com China 40399 62
Alfa Aesar 400-610-6006; 021-67582000
021-67582001/03/05 saleschina@alfa-asia.com China 30308 84
TAIYUAN RHF CO.,LTD. +86 351 7031519
+86 351 7031519 sales@RHFChem.com China 2362 56
TCI (Shanghai) Development Co., Ltd. 021-67121386 / 800-988-0390
021-67121385 Sales-CN@TCIchemicals.com China 24654 81
Energy Chemical 021-58432009 / 400-005-6266
021-58436166-800 info@energy-chemical.com China 44192 61
Shijiazhuang Sdyano Fine Chemical Co., Ltd. 13582355795
4000311741 master@sjzsdyn.com China 5111 65

View Lastest Price from Sasapyrine manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-19 Sasapyrine
552-94-3
US $8.00 / kg 1kg 99% 10MT career henan chemical co
2018-12-19 Sasapyrine
552-94-3
US $8.00 / kg 1kg 99% 10MT career henan chemical co

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