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Sodium Phosphate, Dibasic

CAS No.
7558-79-4
Chemical Name:
Sodium Phosphate, Dibasic
Synonyms
DISODIUM PHOSPHATE;DSP;DISODIUM HYDROGEN PHOSPHATE;DIBASIC SODIUM PHOSPHATE;DSPA;DISODIUM PHOSPHATE DIHYDRATE;BUFFER SOLUTION;Sodium phosphate dibasic anhydrous;SODIUM HYDROGENPHOSPHATE;SODIUM MONOHYDROGEN PHOSPHATE
CBNumber:
CB1242667
Molecular Formula:
Na2HPO4
Molecular Weight:
141.96
MDL Number:
MFCD00003496
MOL File:
7558-79-4.mol
MSDS File:
SDS
Last updated:2024-03-22 11:43:20

Sodium Phosphate, Dibasic Properties

Melting point 243-245 °C
Density 1.064 g/mL at 20 °C
vapor density 4.9 (vs air)
vapor pressure 0Pa at 20℃
FEMA 2398 | DISODIUM PHOSPHATE
storage temp. Store at +5°C to +30°C.
solubility H2O: 0.5 M at 20 °C, clear, colorless
form powder
color White
PH 8.9-9.2 (25℃, 50g/L in water)
pka (1) 2.15, (2) 6.82, (3) 12.38 (at 25℃)
Odor odorless
Water Solubility >=10 g/100 mL at 20 ºC
Sensitive Hygroscopic
λmax λ: 260 nm Amax: 0.019
λ: 280 nm Amax: 0.016
Merck 14,8659
Stability Stable. Incompatible with strong acids. Hygroscopic.
InChIKey BNIILDVGGAEEIG-UHFFFAOYSA-L
LogP -2.15
Substances Added to Food (formerly EAFUS) SODIUM PHOSPHATE, DIBASIC
CAS DataBase Reference 7558-79-4(CAS DataBase Reference)
FDA UNII 22ADO53M6F
EPA Substance Registry System Disodium phosphate (7558-79-4)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-24/25
RIDADR  UN 3077 9 / PGIII
WGK Germany  3
RTECS  WC4500000
3
TSCA  Yes
HS Code  28352200
Toxicity LD50 orally in Rabbit: > 2000 mg/kg
NFPA 704
0
1 1

Sodium Phosphate, Dibasic price More Price(116)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 94046 Sodium phosphate dibasic solution BioUltra, 0.5?M in H2O 7558-79-4 100mL $64.9 2024-03-01 Buy
Sigma-Aldrich NIST2186II Disodium hydrogen phosphate NISTSRM2186II 7558-79-4 30g $947 2024-03-01 Buy
Sigma-Aldrich 94046 Sodium phosphate dibasic solution BioUltra, 0.5?M in H2O 7558-79-4 500mL $196 2024-03-01 Buy
Sigma-Aldrich 567550 Sodium Phosphate, Dibasic - CAS 7558-79-4 - Calbiochem ACS Reagent Grade. Useful in conjunction with Sodium Phosphate, Monobasic in the preparation of biological buffers. 7558-79-4 500g $97 2024-03-01 Buy
Sigma-Aldrich 567547 Sodium Phosphate, Dibasic, Molecular Biology Grade - CAS 7558-79-4 - Calbiochem Useful in conjunction with Sodium Phosphate, Monobasic in the preparation of biological buffers. 7558-79-4 250g $63.3 2024-03-01 Buy
Product number Packaging Price Buy
94046 100mL $64.9 Buy
NIST2186II 30g $947 Buy
94046 500mL $196 Buy
567550 500g $97 Buy
567547 250g $63.3 Buy

Sodium Phosphate, Dibasic Chemical Properties,Uses,Production

Description

Sodium phosphate dibasic is highly hygroscopic and water soluble. Useful in conjunction with Sodium Phosphate, Monobasic in the preparation of biological buffers. It is commonly used in biological assay buffers. Sodium is required for nerve and muscle functioning. Sodium Phosphate Dibasic can be used as a dietary supplement and as a nutrient. Sodium hydrogen phosphate is used in food and water treatment in conjunction with trisodium phosphate.In foods, it is used to adjust pH. In water treatment, It retards calcium scale formation. It is also found in some detergents and cleaning agents. This product is known to be Used in many applications including the purification of antibodies. It is used as a saline laxative to treat constipation or to clean the bowel before a colonoscopy.

Chemical Properties

Sodium hydrogen phosphate,NaH2P04·H20, is hygroscopic, transparent, water-soluble crystals. Used as a purgative, reagent,and buffer.

Chemical Properties

The anhydrous compound is white crystalline powder; hygroscopic; density 1.70 g/cm3; converts to sodium pyrophosphate at 240°C; soluble in water; 874 SODIUM PHOSPHATE, DIBASIC insoluble in alcohol. The dihydrate is a crystalline powder or granular solid; density 2.066 g/cm3 at 15°C; loses water of crystallization at 92.5°C. The heptahydrate is a powdered or granular crystalline solid; density 1.679 g/cm3; loses five molecules of water at 48°C. The dodecahydrate is made up of translucent crystals or granules; density 1.524 g/cm3; readily loses five water molecules on exposure to air at ambient temperature; melts at 35°C when the salt contains all water of crystallization; loses all water at 100°C. All the hydrates are soluble in water and insoluble in alcohol.

Chemical Properties

Disodium phosphate is anhydrous or contains two molecules of water of hydration

Physical properties

The anhydrous compound is white crystalline powder; hygroscopic; density 1.70 g/cm3; converts to sodium pyrophosphate at 240°C; soluble in water;insoluble in alcohol.
The dihydrate is a crystalline powder or granular solid; density 2.066 g/cm3 at 15°C; loses water of crystallization at 92.5°C.
The heptahydrate is a powdered or granular crystalline solid; density 1.679 g/cm3; loses five molecules of water at 48°C.
The dodecahydrate is made up of translucent crystals or granules; density 1.524 g/cm3; readily loses five water molecules on exposure to air at ambient temperature; melts at 35°C when the salt contains all water of crystallization; loses all water at 100°C.
All the hydrates are soluble in water and insoluble in alcohol.

Occurrence

Disodium phosphate is anhydrous or contains two molecules of water of hydration

Uses

Sodium Phosphate Dibasic is used as an in conjunction with trisodium phosphate in foods and water treatment. In foods, it is used to adjust pH. In water treatment, It retards calcium scale formation. It is also found in some detergents and cleaning agents. Sodium Phosphate Dibasic is used as a saline laxative to treat constipation or to clean the bowel before a colonoscopy.

Uses

It is used in pH buffer solutions.

Uses

Sodium Phosphate, Dibasic is used as a laboratory reagent and a buffer in chemical analysis. Other uses are in manufacturing ceramics, detergents, and enamels; as a mordant in dyeing; for fireproofing paper and wood; for weighting and printing silk; in the treatment of boiler water; as a sequestrant in food; as a dietary supplement; in soldering enamels; and in fertilizers. It is used therapeutically as a cathartic.

Preparation

Dibasic sodium phosphate is prepared by treating phosphoric acid with a slight excess of sodium carbonate. The solution is boiled to expel carbon dioxide. Upon cooling dodecahydrate crystallizes out. Heating dodecahydrate at 100°C forms the anhydrous salt.
H3PO4 + Na2CO3 → Na2HPO4 + CO2 + H2O
Dibasic sodium phosphate also is prepared by reacting dibasic calcium phosphate with sodium carbonate. The product calcium carbonate precipitates leaving dibasic sodium salt in the solution. The solution on cooling yields crystals of hydrated product.
CaHPO4 + Na2CO3 → CaCO3 + Na2HPO4

Definition

ChEBI: Disodium hydrogenphosphate is a sodium phosphate.

General Description

Sodium phosphate dibasic in combination with sodium phosphate monobasic is used in the preparation of oral sodium phosphate solution (OSPS), which is a purgative used for bowel cleansing before colonoscopy.

Flammability and Explosibility

Non flammable

Biochem/physiol Actions

Sodium phosphate dibasic is an important component of running buffer of denaturing gel electrophoresis. It induces glomerular calcification as well as other nephrotic syndrome in Sprague-Dawley rats.

Safety Profile

Poison by intravenous route. Moderately toxic by intraperitoneal, subcutaneous, and intramuscular routes. Mildly toxic by ingestion. A skin and eye irritant. When heated to decomposition it emits toxic fumes of POx and Na2O. See also PHOSPHATES.

Purification Methods

Crystallise the salt twice from warm water, by cooling. Dry in air, then in an oven overnight at 130o. It should be dried before use as it is slightly hygroscopic. It forms di-, hepta-and deca-hydrates.

Global( 601)Suppliers
Supplier Tel Email Country ProdList Advantage
Jiangsu Kolod Food Ingredients Co.,Ltd.
+86-518-85110578 +8618805133257 sales3257@jskolod.com China 132 60
Chongqing Chuandong Chemical (Group) Co. Ltd.
+86-13637972665 +86-13637972665 wxc@cd1958.com China 81 58
Hebei Mojin Biotechnology Co., Ltd
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Changzhou Rokechem Technology Co., Ltd.
18758118018 sales001@rokechem.com China 255 58
Henan Fengda Chemical Co., Ltd
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Hebei Saisier Technology Co., LTD
+86-18400010335 +86-13102810335 admin@hbsaisier.cn China 690 58
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714 fandachem@gmail.com China 9348 55
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418679 +86-18949832763 info@tnjchem.com China 2989 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3620 58
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58

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View Lastest Price from Sodium Phosphate, Dibasic manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Sodium Phosphate, Dibasic pictures 2024-04-12 Sodium Phosphate, Dibasic
7558-79-4
US $6.00 / KG 1KG More than 99% 500KG/Month Hebei Saisier Technology Co., LTD
Sodium Phosphate, Dibasic pictures 2023-12-25 Sodium Phosphate, Dibasic
7558-79-4
US $0.00 / kg 1kg 98% 1000000 Hebei Jingbo New Material Technology Co., Ltd
Sodium Phosphate, Dibasic pictures 2023-12-23 Sodium Phosphate, Dibasic
7558-79-4
US $50.00-1.00 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
Sodium phosphate dibasic Vetec(TM) reagent grade, 99% di-Sodium hydrogen phosphate anhydrous for analysis EMSURE ACS,Reag. Ph Eur Sodium phosphate dibasic anhydrous, free-flowing, Redi-Dri, ACS reagent, >=99% SODIUM PHOSPHATE DIBASIC BIOXTRA SODIUM PHOSPHATE DIBASIC SOLUTION 0. SODIUM PHOSPHATE DIBASIC, BIOREAGENT SODIUM PHOSPHATE DIBASIC, REAGENTPLU SODIUM PHOSPHATE, DIBASIC MOLECULAR* Sodium phosphate dibasic, anhydrousFCC, ≥ 99.0% (Titration) Sodium phosphate dibasic, anhydrousUSP, 98.0-100.5% (Assay,on dried basis) Disodium hydrogen phosphate solution di-Sodium hydrogen phosphate solution di-Sodium hydrogen phosphate anhydrous for analysis particle size about 0.2-1 mm (~18-80 mesh ASTM) EMSURE di-Sodium hydrogen phosphate anhydrous suitable for use as excipient EMPROVE exp Ph Eur,BP,USP,E 339 di-Sodium hydrogen phosphate anhydrous 99.99 Suprapur Sodium Phosphate, Dibasic, Molecular Biology Grade DI-SODIUM HYDROG.PHOSP.ANHYD. NAD TRIHYDRATE REAGENT GRADE TAP FOR JERRYCAN DIN42 TAP RED/WHITE 42 MM FLUORINATED Disodium Phosphate Granule Disodium Phosphate Particle Sodium Phosphate Dibasic, Meets analytical specification of Ph.Eur.BP, USP, FCC Buffer Solution pH 7.00 ±0.01, Yellow Sodium phosphate, dibasic, p.a. Sodium Phosphate, Monobasic, Monohydrate, Anhydrous USP SOLUTION BARIUM CHLORIDE SODIUM PHOSPHATE, DIBASIC BIO-REFINED Sodiumhydrogenphosphate,99+%(ACS) buffer solution from di-sodium hydrogen phosphate sodium hydrogen phosphate, anhydrous, acs DIBASICSODIUMPHOSPHATE,DRIED,USP SODIUMPHOSPHATE,DIBASIC,ANHYDROUS,BIOTECHGRADE SODIUMPHOSPHATE,DIBASIC,ANHYDROUS,FCC DISODIUMANDTRISODIUMPHOSPHATESUPPLEMENT SODIUMDIBASICPHOSPHATE DISODIUMMONOPHOSPHATE DINATRIUMHYDROGENPHOSPHATE SODIUM HYDROGEN PHOSPHATE (ACS) DI-SODIUM HYDROGEN PHOSPHATE ANHYDROUS USP, BP, PH EUR DI-SODIUM HYDROGEN PHOSPHATE R. G., BUFF ER SUBSTANCE, REAG. ACS SODIUM PHOSPHATE DIBASIC ANHYDROUS POWDER FCC SODIUM PHOSPHATE DIBASIC DRIED POWDER USP/NF Sodium phophate, dibasic CREATINE ESTER SODIUM PHOSPHATE Disodium hydrogen phosphate, anhydrous, 98+% "Sodium hydrogen phosphate, anhydrous/ 98+%" "Sodium hydrogen phosphate, anhydrous/ 99+%/ ACS" EMPROVE(R) di-SodiuM Hydrogen Phosphate, Anhydrous, USP, BP, Ph Eur SodiuM Phosphate Dibasic, Dried, USP, EP SodiuM Phosphate Dibasic, Reagent, ACS SodiuM phosphate, dibasic, anhydrous, for analysis, 99+% 100GR SodiuM phosphate, dibasic, anhydrous, for analysis, 99+% 500GR SodiuM phosphate, dibasic, suitable for buffer solutions, for analysis ACS, 99+% 500GR DINATRII PHOSPHAS DIHYDRICUS DINATRII PHOSPHAS ANHYDRICUS DISODIUM PHOSHATE DI-SODIUM HYDROGEN ORTHOPHOSPHATE 2H2O