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BML-259

BML-259 structure

CAS No.: 267654-00-2

Chemical Name:: BML-259

Synonyms: BML-259;CAY10554;Benzeneacetamide, N-[5-(1-methylethyl)-2-thiazolyl]-;2-phenyl-N-(5-propan-2-yl-1,3-thiazol-2-yl)acetamide;BML-259,protein,p53,CDK,death,disease,neurotoxicity,cell,Inhibitor,inhibit,Cyclin dependent kinase,Alzheimer's

CBNumber:: CB12450947

Molecular Formula:: C14H16N2OS

Molecular Weight:: 260.35

MDL Number:: MFCD09802287

MOL File:: 267654-00-2.mol

Last updated:2023-09-04 15:51:00

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BML-259 Properties

Melting point	150-152℃
storage temp.	RT
solubility	Soluble in DMSO (up to 25 mg/ml).
form	White solid.
color	white
Stability	Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P280a-P304+P340-P305+P351+P338-P405-P501a

BML-259 price More Price(11)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	SRP0704	BML-259 recombinant	267654-00-2	25mg	$341	2024-03-01	Buy
Alfa Aesar	J67143	BML-259, 98%	267654-00-2	5mg	$139	2023-06-20	Buy
Cayman Chemical	10010301	CAY10554 ≥95%	267654-00-2	5mg	$64	2024-03-01	Buy
Cayman Chemical	10010301	CAY10554 ≥95%	267654-00-2	10mg	$119	2024-03-01	Buy
Cayman Chemical	10010301	CAY10554 ≥95%	267654-00-2	25mg	$280	2024-03-01	Buy

Product number	Packaging	Price	Buy
SRP0704	25mg	$341	Buy
J67143	5mg	$139	Buy
10010301	5mg	$64	Buy
10010301	10mg	$119	Buy
10010301	25mg	$280	Buy

BML-259 Chemical Properties,Uses,Production

Description

BML-259 (267654-00-2) is a potent inhibitor of Cdk5/p25 (IC50 = 64 nM) and Cdk2 (IC50 = 98nM).1

Definition

ChEBI: 2-phenyl-N-(5-propan-2-yl-2-thiazolyl)acetamide is a member of acetamides.

References

1) Helal et al. (2004) Discovery and SAR of 2-aminothiazole inhibitors of cyclin-dependent kinase 5/p25 as a potential treatment for Alzheimer’s disease; Bioorg. Med. Chem. Lett. 14 5521

BML-259 Preparation Products And Raw materials

Raw materials

Preparation Products

BML-259 Suppliers

Global( 40)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
BOC Sciences	16314854226	info@bocsci.com	United States	9926	65
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd	15317229551	15151849396@163.com	China	997	58
InvivoChem	13549236410	sales@invivochem.cn	China	6712	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24131	58
Suzhou Zhixin Biotechnology Co., Ltd.	0512-65118909 15162312715	sales@szzxbio.com	China	2999	58
Shaoguan Qicheng Biotechnology Co., Ltd	18122215013	780229652@qq.com	China	932	58

Supplier	Advantage
Aladdin Scientific	58
BOC Sciences	65
Shanghai EFE Biological Technology Co., Ltd.	58
Shanghai Hongye Biotechnology Co. Ltd	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	58
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd	58
InvivoChem	58
TargetMol Chemicals Inc.	58
Suzhou Zhixin Biotechnology Co., Ltd.	58
Shaoguan Qicheng Biotechnology Co., Ltd	58

BML-259 Spectrum

BML-259(267654-00-2)¹HNMR

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BML-259 CAY10554 2-phenyl-N-(5-propan-2-yl-1,3-thiazol-2-yl)acetamide Benzeneacetamide, N-[5-(1-methylethyl)-2-thiazolyl]- BML-259,protein,p53,CDK,death,disease,neurotoxicity,cell,Inhibitor,inhibit,Cyclin dependent kinase,Alzheimer's 267654-00-2