Triethylene Glycol 2-Bromoethyl Methyl Ether
- CAS No.
- 110429-45-3
- Chemical Name:
- Triethylene Glycol 2-Bromoethyl Methyl Ether
- Synonyms
- mPEG4-Br;m-PEG4-bromo;m-PEG4-bromide;Br-(CH2CH2O)4-Me;Bromo-PEG4-methoxy;Methyl-PEG4-bromide;1-Bromo-3,6,9,12-tetraoxatridecane;13-Bromo-2,5,8,11-tetraoxatridecane;2,5,8,11-Tetraoxatridecane, 13-bromo-;Triethylene Glycol 2-Bromoethyl Methyl Ether
- CBNumber:
- CB12469761
- Molecular Formula:
- C9H19BrO4
- Molecular Weight:
- 271.15
- MDL Number:
- MFCD12545963
- MOL File:
- 110429-45-3.mol
- MSDS File:
- SDS
Boiling point | 296.3±25.0 °C(Predicted) |
---|---|
Density | 1.256±0.06 g/cm3(Predicted) |
refractive index | 1.4620 to 1.4660 |
storage temp. | 2-8°C |
form | clear liquid |
color | White to Yellow to Green |
CAS DataBase Reference | 110429-45-3 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302-H315-H319-H335 | |||||||||
Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 | |||||||||
HS Code | 2909.19.6000 | |||||||||
NFPA 704 |
|
Triethylene Glycol 2-Bromoethyl Methyl Ether price More Price(19)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TCI Chemical | T2634 | Triethylene Glycol 2-Bromoethyl Methyl Ether >95.0%(GC) | 110429-45-3 | 5g | $198 | 2024-03-01 | Buy |
TCI Chemical | T2634 | Triethylene Glycol 2-Bromoethyl Methyl Ether >95.0%(GC) | 110429-45-3 | 25g | $588 | 2024-03-01 | Buy |
TRC | T776665 | Triethylene Glycol 2-Bromoethyl Methyl Ether | 110429-45-3 | 50mg | $45 | 2021-12-16 | Buy |
TRC | T776665 | Triethylene Glycol 2-Bromoethyl Methyl Ether | 110429-45-3 | 100mg | $60 | 2021-12-16 | Buy |
Chem-Impex | 41710 | Triethyleneglycol2-bromoethylmethylether,95%(GC) 95%(GC) | 110429-45-3 | 5G | $230.72 | 2021-12-16 | Buy |
Triethylene Glycol 2-Bromoethyl Methyl Ether Chemical Properties,Uses,Production
Description
m-PEG4-bromide is a PEG linker containing a bromide group. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.
Biological Activity
Triethylene Glycol 2-Bromoethyl Methyl Ether is a cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs) of trastuzumab (HY-P9907). It was placed distal to the monomethyl auristatin E (MMAE) payload to generate ADCs with altered hydrophilicity, antigen binding and in vitro potency. Tetraethylene glycol monotosylate can also be used as a linker of PROTAC, which can be used for the synthesis of PROTAC.
in vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
target
Cleavable
| PEGs
| table>
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
9i LLC | +18039569191 | MWan@NiNeiLab.com | United States | 418 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29822 | 58 |
SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 13363 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Wuhan Borenpharm Co., Ltd | 027-65563561 18717150066 | 3207347307@qq.com | CHINA | 1238 | 58 |
Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | China | 52861 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10522 | 58 |
Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3149 | 58 |
View Lastest Price from Triethylene Glycol 2-Bromoethyl Methyl Ether manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-03-27 | m-PEG4-Br
110429-45-3
|
US $0.00 / g | 25g | >98.00% | 25g | Xian confluore Biological Technology Co., Ltd. | ||
2020-01-10 | Triethylene Glycol 2-Bromoethyl Methyl Ether
110429-45-3
|
US $1.00 / KG | 1KG | 99% | 200kg | Career Henan Chemical Co |
- m-PEG4-Br
110429-45-3
- US $0.00 / g
- >98.00%
- Xian confluore Biological Technology Co., Ltd.
- Triethylene Glycol 2-Bromoethyl Methyl Ether
110429-45-3
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
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