IMIDAZO[1,2-A]PYRAZINE-2-CARBOXYLIC ACID
![IMIDAZO[1,2-A]PYRAZINE-2-CARBOXYLIC ACID Structure](CAS/GIF/77112-53-9.gif)
- CAS No.
- 77112-53-9
- Chemical Name:
- IMIDAZO[1,2-A]PYRAZINE-2-CARBOXYLIC ACID
- Synonyms
- IMIDAZO[1,2-A]PYRAZINE-2-CARBOXYLIC ACID
- CBNumber:
- CB1248609
- Molecular Formula:
- C7H5N3O2
- Molecular Weight:
- 163.13
- MDL Number:
- MFCD08460077
- MOL File:
- 77112-53-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Imidazo[1,2-a]pyrazine-2-carboxylicAcid | I495518 | 100mg | $60 |
| Imidazo[1,2-a]pyrazine-2-carboxylic acid 95% | 057562 | 1g | $1008 |
| Imidazo[1,2-a]pyrazine-2-carboxylicacid | W8372 | 25g | $1368 |
| IMIDAZO[1,2-ALPHA]PYRAZINE-2-CARBOXYLIC ACID 95.00% | CHM0167227 | 1G | $1686.3 |
| Imidazo[1,2-a]pyrazine-2-carboxylicacid 95%+ | CM168532 | 1g | $54 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HazardClass | IRRITANT |
IMIDAZO[1,2-A]PYRAZINE-2-CARBOXYLIC ACID price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | I495518 | Imidazo[1,2-a]pyrazine-2-carboxylicAcid | 77112-53-9 | 100mg | $60 | 2021-12-16 | Buy |
| Matrix Scientific | 057562 | Imidazo[1,2-a]pyrazine-2-carboxylic acid 95% | 77112-53-9 | 1g | $1008 | 2021-12-16 | Buy |
| AK Scientific | W8372 | Imidazo[1,2-a]pyrazine-2-carboxylicacid | 77112-53-9 | 25g | $1368 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0167227 | IMIDAZO[1,2-ALPHA]PYRAZINE-2-CARBOXYLIC ACID 95.00% | 77112-53-9 | 1G | $1686.3 | 2021-12-16 | Buy |
| Chemenu | CM168532 | Imidazo[1,2-a]pyrazine-2-carboxylicacid 95%+ | 77112-53-9 | 1g | $54 | 2021-12-16 | Buy |
IMIDAZO[1,2-A]PYRAZINE-2-CARBOXYLIC ACID Chemical Properties,Uses,Production
Synthesis
![ETHYL IMIDAZO[1,2-A]PYRAZINE-2-CARBOXYLATE](/CAS/GIF/77112-52-8.gif)
77112-52-8
![IMIDAZO[1,2-A]PYRAZINE-2-CARBOXYLIC ACID](/CAS/GIF/77112-53-9.gif)
77112-53-9
Lithium chloride monohydrate (6.50 g, 0.156 mol) was added to ethyl imidazo[1,2-a]pyrazine-2-carboxylate (9.73 g, 0.05 mol) in a mixed ethanol/water (400 mL/100 mL) solvent and the reaction was stirred at room temperature for 8 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure. The pH of the reaction mixture was adjusted to 3-4 with aqueous 1 N hydrochloric acid under cooling in an ice bath and a solid was precipitated. The precipitate was collected by filtration and washed sequentially with acetone and dichloromethane. The filter cake was dried at 50 °C and the residual solvent was removed under reduced pressure to afford imidazo[1,2-a]pyrazine-2-carboxylic acid (7.69 g, 9.4 mmol) in pink solid powder form in 93.7% yield.
References
[1] Patent: CN103965194, 2016, B. Location in patent: Paragraph 0214-0216
[2] Journal of Medicinal Chemistry, 1984, vol. 27, # 2, p. 206 - 212
[3] Farmaco, Edizione Scientifica, 1981, vol. 36, # 1, p. 61 - 80
IMIDAZO[1,2-A]PYRAZINE-2-CARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52705 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
| Coresyn Pharmatech Co., Ltd. | +86-571-86626709 +86-18157142896 | cbc@coresyn.com | China | 9984 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; | peter68@ptchemgroup.com | China | 35425 | 58 |
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