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ELASTATINAL

ELASTATINAL structure

CAS No.: 51798-45-9

Chemical Name:: ELASTATINAL

Synonyms: ELASTATINAL;AIDS-006470;Leu-co-cpd-Gln-Ala-h;ELASTATINAL USP/EP/BP;elastatinal from microbial source;N-[-N-ALPHA-CARBONYL-CPD-GLN-ALA-AL]-LEU;l-glutamamide,l-2-(2-amino-1,4,5,6-tetrahydro-4-pyrimidinyl-n-(((1-carboxy-3-m;N-[(S)-1-CARBOXYISOPENTYL]CARBAMOYL-ALPHA-[2-IMINOHEXAHYDRO-4(S)-PYRIMIDYL-(S)-GLYCYL-(S)-GLUTAMINYL-(S)-ALANINAL];Nα-[2-(2-Amino-1,4,5,6-tetrahydropyrimidin-4-yl)-N-[[(1-carboxy-3-methylbutyl)amino]carbonyl]-L-glycyl]-N1-(1-methyl-2-oxoethyl)-L-glutaminamide;L-Glutamamide, (2S)-2-(4S)-2-amino-1,4,5,6-tetrahydro-4-pyrimidinyl-N-(1S)-1-carboxy-3-methylbutylaminocarbonylglycyl-N1-(1S)-1-methyl-2-oxoethyl-

CBNumber:: CB1249000

Molecular Formula:: C21H36N8O7

Molecular Weight:: 512.56

MDL Number:: MFCD00151180

MOL File:: 51798-45-9.mol

MSDS File:: SDS

Last updated:2023-05-18 11:31:03

Request For Quotation

ELASTATINAL Properties

storage temp.	-20°C
solubility	H₂O: 20 mg/mL, clear, yellow
form	Yellow solid.
color	off-white
BRN	873543
Stability	Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.
FDA UNII	LX4Y75DOA7

SAFETY

Risk and Safety Statements

Safety Statements	22-24/25
WGK Germany	3
RTECS	LZ9600000
F	10

ELASTATINAL price More Price(13)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	E0881	Elastatinal microbial	51798-45-9	5mg	$181	2024-03-01	Buy
Sigma-Aldrich	E0881	Elastatinal microbial	51798-45-9	10mg	$330	2024-03-01	Buy
Alfa Aesar	J61120	Elastatinal	51798-45-9	5mg	$147	2023-06-20	Buy
Alfa Aesar	J61120	Elastatinal	51798-45-9	25mg	$432	2021-12-16	Buy
Cayman Chemical	22288	Elastatinal ≥95%	51798-45-9	5mg	$93	2024-03-01	Buy

Product number	Packaging	Price	Buy
E0881	5mg	$181	Buy
E0881	10mg	$330	Buy
J61120	5mg	$147	Buy
J61120	25mg	$432	Buy
22288	5mg	$93	Buy

ELASTATINAL Chemical Properties,Uses,Production

Description

Elastatinal is a potent inhibitor of pancreatic elastase (K_i = 240 nM) that is produced by various species of Actinomycetes. It more strongly inhibits pancreatic elastase versus the leukocyte-derived enzyme. Elastatinal reduces electrophoretic mobilities of 2A proteinases from poliovirus and human rhinovirus 14 in a dose-dependent manner, indicating substrate recognition by 2A proteinases is similar to that of pancreatic elastases. It can also inhibit elastase-like protease collagenolytic protease from C. maenas digestive glands.

Uses

Elastatinal is an elastase inhibitor.

Biochem/physiol Actions

Potent, irreversible elastase inhibitor. Elastatinal is a much stronger inhibitor of elastase from pancreas than from leucocytes.

References

1) Umezawa et al. (1973), Letter: Elastatinal, a new elastase inhibitor produced by actinomycetes; J. Antibiotics, 26 787 2) Nakajima et al. (1992), Identification of elastase as a secretory protease from cultured rat microglia; J. Neurochem., 58 1401 3) Molla et al. (1993), Inhibition of proteolytic activity of poliovirus and rhinovirus 2A proteases by elastase-specific inhibitors; J. Virol., 67 4688 4) Menendez-Arias et al. (1992), Isolation and characterization of alpha 2-macroglobulin-protease complexes from purified mouse mammary tumor virus and culture supernatants from virus-infected cell lines; J. Biol. Chem., 267 11392

ELASTATINAL Preparation Products And Raw materials

Raw materials

Preparation Products

ELASTATINAL Suppliers

Global( 77)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Alpha Biopharmaceuticals Co., Ltd	+86-411-39042497 +8613921981412	sales@alphabiopharm.com	China	886	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29271	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19915	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
DONBOO AMINO ACID COMPANY	+8613063595538	donboo@donboo.com	China	9365	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
Alabiochem Tech.Co., Ltd.	0512-58900862 400-0707518	sales@alabiochem.com	China	995	59

Supplier	Advantage
Alpha Biopharmaceuticals Co., Ltd	58
Hubei xin bonus chemical co. LTD	58
career henan chemical co	58
TargetMol Chemicals Inc.	58
Dideu Industries Group Limited	58
Nextpeptide Inc	58
Aladdin Scientific	58
DONBOO AMINO ACID COMPANY	58
3B Pharmachem (Wuhan) International Co.,Ltd.	69
Alabiochem Tech.Co., Ltd.	59

View Lastest Price from ELASTATINAL manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-01-09	ELASTATINAL 51798-45-9	US $1.00 / g	1g	≥98%	g/kg/Ton	Career Henan Chemical Co

ELASTATINAL
51798-45-9
US $1.00 / g
≥98%
Career Henan Chemical Co

51798-45-9(ELASTATINAL)Related Search:

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ELASTATINAL Dibutylurea

1of2

N-[-N-ALPHA-CARBONYL-CPD-GLN-ALA-AL]-LEU elastatinal from microbial source L-2-(2-amino-1,4,5,6-tetrahydro-4-pyrimidinyl)-N-[[(1-carboxy-3-methylbutyl)amino]carbonyl]glycyl-N1-(1-methyl-2-oxoethyl)-L-glutamamide, stereoisomer Leu-co-cpd-Gln-Ala-h L-Glutamamide, (2S)-2-(4S)-2-amino-1,4,5,6-tetrahydro-4-pyrimidinyl-N-(1S)-1-carboxy-3-methylbutylaminocarbonylglycyl-N1-(1S)-1-methyl-2-oxoethyl- (2s)-2-[(4s)-2-amino-1,4,5,6-tetrahydro4-pyrimidinyl]-n-[[[(1s)-1-carboxy-3-methylbutyl]amino]carbonyl]glycyl-n1-[(1s)-1-methyl-2-oxoethyl-l-glutamamide AIDS-006470 Nα-[2-(2-Amino-1,4,5,6-tetrahydropyrimidin-4-yl)-N-[[(1-carboxy-3-methylbutyl)amino]carbonyl]-L-glycyl]-N1-(1-methyl-2-oxoethyl)-L-glutaminamide (2S)-2-[(4S)-2-Amino-3,4,5,6-tetrahydro-4-pyrimidinyl]-N-[[[(1S)-1-carboxy-3-methylbutyl]amino]carbonyl]glycyl-N1-[(1S)-1-methyl-2-oxoethyl]-L-glutamamide l-glutamamide,l-2-(2-amino-1,4,5,6-tetrahydro-4-pyrimidinyl-n-(((1-carboxy-3-m ELASTATINAL N-[(S)-1-CARBOXYISOPENTYL]CARBAMOYL-ALPHA-[2-IMINOHEXAHYDRO-4(S)-PYRIMIDYL-(S)-GLYCYL-(S)-GLUTAMINYL-(S)-ALANINAL] L-Glutamamide, (2S)-2-[(4S)-2-amino-3,4,5,6-tetrahydro-4-pyrimidinyl]-N-[[[(1S)-1-carboxy-3-methylbutyl]amino]carbonyl]glycyl-N1-[(1S)-1-methyl-2-oxoethyl]- ELASTATINAL USP/EP/BP (2S)-2-[[(1S)-2-[[(2S)-5-amino-1,5-dioxo-1-[[(2S)-1-oxopropan-2-yl]amino]pentan-2-yl]amino]-1-(2-amino-1,4,5,6-tetrahydropyrimidin-6-yl)-2-oxoethyl]carbamoylamino]-4-methylpentanoic acid 51798-45-9 C21H36N8O7 C21H36N8O6 P to Q Plasmin Organic Covalent Modifiers Enzyme Inhibitors Enzyme Inhibitors by Enzyme Enzyme Inhibitors by Type Enzymes, Inhibitors, and Substrates BioChemical Biochemicals and Reagents Enzymes Inhibitors Miscellaneous Peptides Organic Building Blocks P to Q Peptides and Proteins Peptides for Cell Biology Plasmin Protease Inhibitor Specificity Index Protease Inhibitors Proteins and Derivatives Pepetides peptides Blood Proteins Plasma & Aldehydes and Substrates Bioactive Small Molecules Biochemicals and Reagents Building Blocks C13-C60 Carbonyl Compounds Cell Biology Cell Signaling and Neuroscience Chemical Synthesis Coagulation Proteins and Reagents E Enzyme Inhibitors Enzyme Inhibitors by Enzyme