ChemicalBook >> CAS DataBase List >>[4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-Methylsulfonyl-2-[((S)-2,2,2-trifluoro-1-methylethyl)oxy]phenyl]methanone

[4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-Methylsulfonyl-2-[((S)-2,2,2-trifluoro-1-methylethyl)oxy]phenyl]methanone

[4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-Methylsulfonyl-2-[((S)-2,2,2-trifluoro-1-methylethyl)oxy]phenyl]methanone structure

CAS No.: 845614-11-1

Chemical Name:: [4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-Methylsulfonyl-2-[((S)-2,2,2-trifluoro-1-methylethyl)oxy]phenyl]methanone

Synonyms: RG1678;RG1679;RO4917838;Bitopertin;Paliflutine;RG1678, RO-4917838;Palufidine,RG-1678;Bitopertin (RG-1678;inhibit,Bitopertin,RG 1678,RO-4917838,RG-1678,GlyT,Inhibitor,RO 4917838,Glycine transporters;(S)-[4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-(methanesulfonyl)-2-(2,2,2-trifluoro-1-methylethoxy)phenyl]methanone

CBNumber:: CB12546501

Molecular Formula:: C21H20F7N3O4S

Molecular Weight:: 543.46

MDL Number:: MFCD18251496

MOL File:: 845614-11-1.mol

MSDS File:: SDS

Last updated:2023-07-12 17:15:10

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[4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-Methylsulfonyl-2-[((S)-2,2,2-trifluoro-1-methylethyl)oxy]phenyl]methanone Properties

Boiling point	635.1±55.0 °C(Predicted)
Density	1.444
storage temp.	Store at -20°C
solubility	insoluble in H2O; ≥17.94 mg/mL in EtOH; ≥88.9 mg/mL in DMSO with ultrasonic
form	crystalline solid
pka	3.57±0.39(Predicted)
FDA UNII	Q8L6AN59YY

[4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-Methylsulfonyl-2-[((S)-2,2,2-trifluoro-1-methylethyl)oxy]phenyl]methanone price More Price(25)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	19896	Bitopertin ≥98%	845614-11-1	10mg	$121	2024-03-01	Buy
Cayman Chemical	19896	Bitopertin ≥98%	845614-11-1	25mg	$287	2024-03-01	Buy
Cayman Chemical	19896	Bitopertin ≥98%	845614-11-1	50mg	$543	2024-03-01	Buy
Cayman Chemical	19896	Bitopertin ≥98%	845614-11-1	100mg	$961	2024-03-01	Buy
TRC	B591450	Bitopertin	845614-11-1	50mg	$5225	2021-12-16	Buy

Product number	Packaging	Price	Buy
19896	10mg	$121	Buy
19896	25mg	$287	Buy
19896	50mg	$543	Buy
19896	100mg	$961	Buy
B591450	50mg	$5225	Buy

[4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-Methylsulfonyl-2-[((S)-2,2,2-trifluoro-1-methylethyl)oxy]phenyl]methanone Chemical Properties,Uses,Production

Uses

Bitopertin is a potent and noncompetitive glycine reuptake inhibitor (GRI). Bitopertin is an investigational agent for the treatment of schizophrenia.

[4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-Methylsulfonyl-2-[((S)-2,2,2-trifluoro-1-methylethyl)oxy]phenyl]methanone Preparation Products And Raw materials

Raw materials

Preparation Products

[4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-Methylsulfonyl-2-[((S)-2,2,2-trifluoro-1-methylethyl)oxy]phenyl]methanone Suppliers

Global( 76)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
Biochempartner	0086-13720134139	candy@biochempartner.com	CHINA	967	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	47465	58
Hefei Hirisun Pharmatech Co., Ltd	+8615056975894	shawn@hirisunpharm.com	CHINA	9923	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418684 +8618949823763	sales@tnjchem.com	China	25363	58
LEAP CHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	24738	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Seasons Biotechnology Co., Ltd.	+86-0576-89232655 +86-13566878689	info@seasonsbio.com	China	46	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
Biochempartner	58
CONIER CHEM AND PHARMA LIMITED	58
Hefei Hirisun Pharmatech Co., Ltd	58
InvivoChem	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
LEAP CHEM CO., LTD.	58
TargetMol Chemicals Inc.	58
Seasons Biotechnology Co., Ltd.	58
Wuhan Topule Biopharmaceutical Co., Ltd	58

[4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-Methylsulfonyl-2-[((S)-2,2,2-trifluoro-1-methylethyl)oxy]phenyl]methanone Spectrum

[4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-Methylsulfonyl-2-[((S)-2,2,2-trifluoro-1-methylethyl)oxy]phenyl]methanone(845614-11-1)¹HNMR

[4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-Methylsulfonyl-2-[((S)-2,2,2-trifluoro-1-methylethyl)oxy]phenyl]methanone Paliflutine Palufidine,RG-1678 RG1678 Bitopertin RO4917838 RG1679 (S)-[4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-(methanesulfonyl)-2-(2,2,2-trifluoro-1-methylethoxy)phenyl]methanone Methanone, [4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]-1-piperazinyl][5-(methylsulfonyl)-2-[(1S)-2,2,2-trifluoro-1-methylethoxy]phenyl]- RG1678, RO-4917838 Bitopertin (RG-1678 (S)-(4-(3-Fluoro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)(5-(methylsulfonyl)-2-((1,1,1-trifluoropropan-2-yl)oxy)phenyl)methanone inhibit,Bitopertin,RG 1678,RO-4917838,RG-1678,GlyT,Inhibitor,RO 4917838,Glycine transporters 845614-11-1 C21H20F7N3O4S Amines Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Sulfur & Selenium Compounds