MPEG5-NHS
- CAS No.
- 1449390-12-8
- Chemical Name:
- MPEG5-NHS
- Synonyms
- mPEG5-SPA;mPEG6-NHS;MPEG5-NHS;m-PEG6-NHS ester;Methyl-PEG5-NHS ester;mPEG5-CH2CH2COONHS Ester;4,7,10,13,16,19-Hexaoxaeicosanoic acid, 2,5-dioxo-1-pyrrolidinyl ester;mPEG5-CH2CH2COONHS/4,7,10,13,16,19-Hexaoxaeicosanoic acid, 2,5-dioxo-1-pyrrolidinyl ester
- CBNumber:
- CB12546945
- Molecular Formula:
- C18H31NO10
- Molecular Weight:
- 421.44
- MDL Number:
- MFCD27977519
- MOL File:
- 1449390-12-8.mol
MPEG5-NHS price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | P999900 | mPEG5-CH2CH2COONHSEster | 1449390-12-8 | 500mg | $310 | 2021-12-16 | Buy |
| BroadPharm | BP-22086 | m-PEG6-NHSester 98% | 1449390-12-8 | 500mg | $350 | 2021-12-16 | Buy |
| chempep | 281307 | mPEG6-NHS >=95% | 1449390-12-8 | 500mg | $360 | 2021-12-16 | Buy |
| AK Scientific | 0500AP | mPEG5-NHS | 1449390-12-8 | 1g | $451 | 2021-12-16 | Buy |
| chempep | 281307 | mPEG6-NHS >=95% | 1449390-12-8 | 1g | $540 | 2021-12-16 | Buy |
MPEG5-NHS Chemical Properties,Uses,Production
Description
m-PEG6-NHS ester is a PEG linker containing an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The hydrophilic PEG spacer increases solubility in aqueous media.
Biological Activity
MPEG5-NHS is a non-cleavable 6-unit PEG-containing ADC linker for the synthesis of antibody drug conjugates (ADCs). It is a PROTAC linker belonging to the PEG/Alkyl/ether class, which can be used to synthesize PROTAC molecules.
in vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
target
| PEGs
| Alkyl/ether
| Non-cleavable
|
MPEG5-NHS Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 9i LLC | +18039569191 | MWan@NiNeiLab.com | United States | 418 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Wuhan Borenpharm Co., Ltd | 027-65563561 18717150066 | 3207347307@qq.com | CHINA | 1238 | 58 |
| Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3149 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19915 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42057 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 +86-15680926068 | 1924344760@confluore.cn | China | 2893 | 58 |
| Daicel Chiral Technologies (China)CO.,LTD | 021-50460086-9 15921403865 | han_yajun@dctc.daicel.com | China | 6818 | 65 |
View Lastest Price from MPEG5-NHS manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-03-27 | m-PEG6-NHS ester
1449390-12-8
|
US $0.00 / g | 1g | >98.00% | 1g | Xian confluore Biological Technology Co., Ltd. |
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- m-PEG6-NHS ester
1449390-12-8
- US $0.00 / g
- >98.00%
- Xian confluore Biological Technology Co., Ltd.