ChemicalBook >> CAS DataBase List >>Sodium salicylate

Sodium salicylate

CAS No.
54-21-7
Chemical Name:
Sodium salicylate
Synonyms
SALICYLATE;NASAL;alysine;2-Hydroxybenzoate;clin;ardall;aroall;kerosal;nadisal;salisod
CBNumber:
CB1255762
Molecular Formula:
C7H5NaO3
Molecular Weight:
160.1
MDL Number:
MFCD00002440
MOL File:
54-21-7.mol
MSDS File:
SDS
Last updated:2024-01-11 09:10:12

Sodium salicylate Properties

Melting point >300 °C (lit.)
Density 0.32 g/cm3 (20℃)
storage temp. Store at +15°C to +25°C.
solubility 1000g/l
form Crystals or Crystalline Powder
color White
Odor wh. lustrous cryst. scales or amorphous powd., odorless or faint odor, saline taste
PH 6.5 (100g/l, H2O, 20℃)
Water Solubility 1000 g/L (20 ºC)
Sensitive Light Sensitive
Merck 14,8332
BRN 3732792
Stability Stable. Incompatible with mineral acids, metallic salts, iodine. May be light-sensitive.
InChIKey ABBQHOQBGMUPJH-UHFFFAOYSA-M
LogP 2.061 (est)
CAS DataBase Reference 54-21-7(CAS DataBase Reference)
Indirect Additives used in Food Contact Substances SODIUM SALICYLATE
FDA 21 CFR 175.105; 310.545
EWG's Food Scores 1
NCI Dictionary of Cancer Terms nasal; sodium salicylate
FDA UNII WIQ1H85SYP
NCI Drug Dictionary sodium salicylate
ATC code N02BA04
EPA Substance Registry System Sodium salicylate (54-21-7)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS08
Signal word  Warning
Hazard statements  H302-H319-H361d
Precautionary statements  P201-P202-P264-P301+P312-P305+P351+P338-P308+P313
Hazard Codes  Xn,Xi
Risk Statements  22-41-36/37/38-36
Safety Statements  26-36
WGK Germany  1
RTECS  VO5075000
8
Autoignition Temperature >250 °C
TSCA  Yes
HS Code  29182100
Toxicity LD50 i.p. in rats: 780 mg/kg (Goldenthal)
NFPA 704
1
2 1

Sodium salicylate price More Price(42)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR3238 Sodium Salicylate pharmaceutical secondary standard, certified reference material 54-21-7 1G $173 2024-03-01 Buy
Sigma-Aldrich 567630 Sodium Salicylate - CAS 54-21-7 - Calbiochem A cell-permeable, non-steroidal anti-inflammatory agent that interferes with TNF-induced NF-κB activation by inhibiting phosphorylation and subsequent degradation of the IκB-α protein. 54-21-7 5G $56.2 2024-03-01 Buy
Sigma-Aldrich 31493 Sodium salicylate puriss. p.a., Reag. Ph. Eur., 99.5-101.0% (calc. to the dried substance) 54-21-7 1kg $208 2024-03-01 Buy
Sigma-Aldrich 1.06601 Sodium salicylate for analysis EMSURE? 54-21-7 250g $79.1 2024-03-01 Buy
Sigma-Aldrich 1614636 Sodium salicylate United States Pharmacopeia (USP) Reference Standard 54-21-7 500mg $420 2024-03-01 Buy
Product number Packaging Price Buy
PHR3238 1G $173 Buy
567630 5G $56.2 Buy
31493 1kg $208 Buy
1.06601 250g $79.1 Buy
1614636 500mg $420 Buy

Sodium salicylate Chemical Properties,Uses,Production

Description

Sodium salicylate is a sodium salt of salicylic acid. It can be prepared from sodium phenolate and carbon dioxide under higher temperature and pressure. Historically, it has been synthesized from methyl salicylate (found in wintergreen plants or the bark of sweet birch tree) by reacting it with an excess of sodium hydroxide and heating it under reflux.

Chemical Properties

Sodium salicylate is of the salicylate family and this compound is known to trigger Reye's Syndrome in children and adults, usually following a viral infection such as influenza or chicken pox. Products containing such salicylates should not be given to children under the age of 19.

Chemical Properties

Sodium salicylate, HOC6H4COONa, is a shiny, white powder with sweetish taste and mild aromatic aroma that is soluble in water,glycerol, and alcohol.Used in medicine and as a preservative.

Uses

It is used in medicine as an analgesic and antipyretic. Sodium salicylate also acts as non - steroidal anti - inflammatory drug (NSAID), and induces apoptosis in cancer cells and also necrosis. It is also a potential replacement for aspirin for people sensitive to it. It may also be used as a phosphor for the detection of vacuum ultra violet radiation and electrons.

Uses

keratolytic

Uses

In manufacture of aspirin, methyl salicylate, and other salicylates. Coupling agent for azo dyes. Has been used as food preservative.

Definition

A salt or ester of salicylic acid.

brand name

Alysine (Marion Merrell Dow).

General Description

Sodium salicylate may be prepared by the reaction, in aqueoussolution, by adding equal molar ratio of salicylic acidand sodium bicarbonate; evaporating to dryness yields thewhite salt. In solution, particularly in the presence of sodiumbicarbonate, the salt will darken on standing. This is the saltof choice for salicylate medication and usually is administeredwith sodium bicarbonate to lessen gastric distress, or itis administered in enteric coated tablets. However, the useof sodium bicarbonate is ill advised, because it decreases theplasma levels of salicylate and increases the excretion offree salicylate in the urine.
Sodium salicylate, even though not as potent as aspirinfor pain relief, also has less GI irritation and is useful for patientswho are hypersensitive to aspirin.

Biochem/physiol Actions

Cell permeable: yes

Safety Profile

Experimental poison by subcutaneous route. Moderately toxic to humans by ingestion. Moderately toxic experimentally by ingestion, intraperitoneal, and intravenous routes. An experimental teratogen. Human systemic effects by multiple and unspecified routes: toxic psychosis, excitement, respiratory stimulation, nausea or vomiting, and sweating. Experimental reproductive effects. Mutation data reported. A powerful irritant which affects the central nervous system. Incompatible with ferric salts, mineral acids, iodme, lead acetate, silver nitrate, sodium phosphate powder. When heated to decomposition it emits toxic fumes of Na2O.

124-38-9
139-02-6
54-21-7
Synthesis of Sodium salicylate from Carbon dioxide and Sodium benzenolate
Global( 559)Suppliers
Supplier Tel Email Country ProdList Advantage
Xiamen AmoyChem Co., Ltd
+86-592-6051114 +8618959220845 sales@amoychem.com China 6387 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21703 55
Shanghai Time Chemicals CO., Ltd.
+86-021-57951555 +8617317452075 jack.li@time-chemicals.com China 1807 55
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714 fandachem@gmail.com China 9359 55
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418679 +86-18949832763 info@tnjchem.com China 2989 55
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29919 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293 sales@sdzschem.com China 2931 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503282 alice@crovellbio.com China 8823 58
HubeiwidelychemicaltechnologyCo.,Ltd
18627774460 faith@widelychemical.com CHINA 742 58
Shandong chuangyingchemical Co., Ltd.
18853181302 sale@chuangyingchem.com CHINA 5909 58

Related articles

  • Sodium Salicylate vs Aspirin
  • Sodium salicylate is a metabolite of acetylsalicylic acid (sc-217570), and functions by inhibiting NF κ B and reduces oxidativ....
  • Jan 20,2022

View Lastest Price from Sodium salicylate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Sodium salicylate pictures 2023-09-19 Sodium salicylate
54-21-7
US $0.00-0.00 / kg 1kg 0.99 50000kg Hebei Yibangte Import and Export Co. , Ltd.
Sodium salicylate pictures 2023-09-06 Sodium salicylate
54-21-7
US $0.00-0.00 / KG 1KG 99% 500000kg Hebei Guanlang Biotechnology Co., Ltd.
Sodium Salicylate pictures 2023-04-17 Sodium Salicylate
54-21-7
US $10.00 / ASSAYS 1ASSAYS 99% 200ton Shanghai Yunao International Trade Co., Ltd
  • Sodium salicylate pictures
  • Sodium salicylate
    54-21-7
  • US $0.00-0.00 / kg
  • 0.99
  • Hebei Yibangte Import and Export Co. , Ltd.
  • Sodium Salicylate pictures
  • Sodium Salicylate
    54-21-7
  • US $10.00 / ASSAYS
  • 99%
  • Shanghai Yunao International Trade Co., Ltd
Sdium salicylate Sodium Salicylate 2-Hydroxybenzoic acid monosodium salt Sodium o-hydroxybenzoate Sodium salicylate BP98 SODIUM SALICYLATE R. G., REAG. PH. EUR. SODIUM SALICYLATE, REAGENTPLUS TM, >= 99.5% SODIUM SALICYLATE, PH EUR SODIUM SALICYLATE, REAGENTPLUS, >=99% SodiumSalicylatePurified SodiumSalicylateGr Sodiumsalicylate,99% NATRII SALICYLAS SALICYCLIC ACID, SODIUM SALT SALICYLIC ACID SODIUM SALT SALICYLIC ACID, NA SODIUM 2-HYDROXYBENZOATE SODIUM SALICYLATE Benzoicacid,2-hydroxy-,monosodiumsalt 2-Hydroxybenzoic acid sodium salt, Salicylic acid sodium salt 2-Hydroxybenzoic acid sodium salt, Natrii salicylas, Salicylic acid sodium salt Camporisin Glutosalyl Idocyll novum 2-Hydroxybenzoic acid anion Salicylic acid anion SODIUMSALICYLATE,CRYSTAL,REAGENT SODIUMSALICYLATE,CRYSTAL,USP Sodium Salicylate, Crystal Sodium salicylate,2-Hydroxybenzoic acid sodium salt, Salicylic acid sodium salt Sodium Salicylate (500 mg) Salicylic acid, sodium salt, 99+% SODIUM SALICYLATE REAGENT Salicylic acid, sodiuM salt, 99+% 1KG Salicylic acid, sodiuM salt, 99+% 250GR SODIUM SALICYLATE FOR ANALYSIS EMSURE ardall aroall Sodium salicylate puriss. p.a., Reag. Ph. Eur., 99.5-101.0% (calc. to the dried substance) Sodium salicylate Vetec(TM) reagent grade, 99% SODIUM SALICYLATE CRYSTALLIZED SODIUM SALICYLATE, REAGENTPLUS TM, > salicylic acid sodium sodium salicylate usp Sodium Salicylate/Salicylic acid sodium salt Sodium sallicylate SODIUM SALICYLATE TECHNICAL GRADE clin diuretin enterosalicyl enterosalil idocylnovum kerasalicyl kerosal magsalyl monosodium2-hydroxybenzoate nadisal natriumsalicylat neo-salicyl o-hydroxybenzoicsodiumsalt