ChemicalBook >> CAS DataBase List >>4-Hydroxytolbutamide
4-Hydroxytolbutamide
- CAS No.
- 5719-85-7
- Chemical Name:
- 4-Hydroxytolbutamide
- Synonyms
- HYDROXY TOLBUTAMIDE;Tolbutamide Hydroxy;4-HYDROXYTOLBUTAMIDE;Tolbutamide Impurity 4;hydroxymethyltolbutamide;HydroxyMethylcarbutaMide;HydroxyMethylcarbutaMide Impurity;4-Hydroxytolbutamide solution ;4-Hydroxytolbutamide Solution, 100ppm;1-Butyl-3-(p-hydroxyMethylphenyl)sulfonylurea
- CBNumber:
- CB1258804
- Molecular Formula:
- C12H18N2O4S
- Molecular Weight:
- 286.35
- MDL Number:
- MFCD00144466
- MOL File:
- 5719-85-7.mol
- MSDS File:
- SDS
Last updated:2023-05-18 11:31:22
| Melting point | 100-102 °C |
|---|---|
| Density | 1.268±0.06 g/cm3(Predicted) |
| Flash point | 2℃ |
| storage temp. | 2-8°C |
| solubility | ethanol: 12 mg/mL |
| pka | 4.96±0.10(Predicted) |
| form | Solid |
| color | white |
| FDA UNII | 52K8J94779 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|---|---|
| Signal word | Danger |
| Hazard statements | H225-H302+H312+H332-H319 |
| Precautionary statements | P210-P261-P302+P352+P312-P304+P340+P312-P337+P313-P403+P235 |
| Hazard Codes | F,Xn |
| Risk Statements | 11-20/21/22-36 |
| Safety Statements | 16-36/37-24/25 |
| RIDADR | UN 1648 3 / PGII |
| WGK Germany | 3 |
| HS Code | 29350090 |
4-Hydroxytolbutamide price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | UC160 | 4-Hydroxytolbutamide ≥98% (HPLC) | 5719-85-7 | 5mg | $896 | 2024-03-01 | Buy |
| Cayman Chemical | 10008520 | 4-hydroxy Tolbutamide ≥98% | 5719-85-7 | 1mg | $41 | 2024-03-01 | Buy |
| Cayman Chemical | 10008520 | 4-hydroxy Tolbutamide ≥98% | 5719-85-7 | 5mg | $153 | 2024-03-01 | Buy |
| Sigma-Aldrich | UC160 | 4-Hydroxytolbutamide ≥98% (HPLC) | 5719-85-7 | 10mg | $1660 | 2024-03-01 | Buy |
| Cayman Chemical | 10008520 | 4-hydroxy Tolbutamide ≥98% | 5719-85-7 | 10mg | $286 | 2024-03-01 | Buy |
4-Hydroxytolbutamide Chemical Properties,Uses,Production
Description
4-hydroxy Tolbutamide is a cytochrome P450 2C8 (CYP2C8) and CYP2C9 metabolite of tolbutamide, a first-generation potassium channel blocker. Tolbutamide 4-hydroxylation is an often used probe reaction in the pharmaceutical industry for the characterization of CYP2C8 and CYP2C9 involvement in the metabolism of clinical drugs.
Chemical Properties
White Solid
Uses
4-Hydroxytolbutamide has been used as a standard to assay the fungal biotransformation of tolbutamide to 4′-hydroxytolbutamide.
Uses
A metabolite of Tolbutamide. Formed by the cytochrome CYP2CIIC8 and IIC9 subfamily of P450 enzymes
Definition
ChEBI: A urea that consists of 1-butylurea having a 4-hydroxymethylbenzenesulfonyl group attached at the 3-position.
4-Hydroxytolbutamide Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 76)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4242 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 | admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com | China | 20000 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
| Artis Chemistry (Shanghai) Co. Ltd. | 86-21-60936353 | China | 336 | 58 | |
| Clearsynth Labs Limited | +91-22-26355700 | info@clearsynth.com | India | 9685 | 58 |
5719-85-7(4-Hydroxytolbutamide)Related Search:
3-Aminobenzenesulfonamide
Sulfanilamide
Tosyl chloride
Benzenesulfonamide
N-n-Butyl benzene sulfonamide
Butylated Hydroxytoluene
p-Toluenesulfonamide
Tris(hydroxymethyl)aminomethane
Tosyl cyanide
TOLBUTAMIDE
1of4
4-HYDROXYTOLBUTAMIDE
HYDROXY TOLBUTAMIDE
N-(BUTYLAMINOCARBONYL)-4-HYDROXYMETHYLBENZENESULFONAMIDE
N-(Butylamnocarbonyl)-4-hydroxymethylbenzenesulfonamide
hydroxymethyltolbutamide
4-Hydroxytolbutamide,N-(Butylaminocarbonyl)-4-hydroxymethylbenzenesulfonamide
1-Butyl-3-(p-hydroxyMethylphenyl)sulfonylurea
HydroxyMethylcarbutaMide
4-Hydroxytolbutamide solution
N-(butylcarbamoyl)-4-(hydroxymethyl)benzenesulfonamide
1-butyl-3-[4-(hydroxymethyl)phenyl]sulfonylurea
4-Hydroxytolbutamide Solution, 100ppm
Tolbutamide Hydroxy
Benzenesulfonamide, N-[(butylamino)carbonyl]-4-(hydroxymethyl)-
Tolbutamide Impurity 4
HydroxyMethylcarbutaMide Impurity
5719-85-7
C12H18N2O4S
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